Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Karen E. Strunk"'
Publikováno v:
Journal of Mammary Gland Biology and Neoplasia. 13:235-246
The ErbB receptor tyrosine kinase family has often been associated with increased growth of breast epithelial cells, as well as malignant transformation and progression. In contrast, ErbB4/HER4 exhibits unique attributes from a two step proteolytic c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa8806691801fb3f1a04d647b04a88e
https://doi.org/10.1007/s10911-008-9080-x
https://doi.org/10.1007/s10911-008-9080-x
Publikováno v:
Placenta. 28:1211-1218
Homozygosity for the Egfr tm1Mag null allele in mice leads to genetic background dependent placental abnormalities and embryonic lethality. Molecular mechanisms or genetic modifiers that differentiate strains with surviving versus non-surviving Egfr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605579d85b207df0c5e0f58c485dd099
https://doi.org/10.1016/j.placenta.2007.07.005
https://doi.org/10.1016/j.placenta.2007.07.005
Publikováno v:
Developmental Biology. 185(2):185-200
Pax1 and QmyoD are early sclerotome and myotome-specific genes that are activated in epithelial somites of quail embryos in response to axial notochord/neural tube signals. In situ hybridization experiments reveal that the developmental kinetics of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c381e3da949daf550e6826180e2adbd9
Autor:
Elizabeth F. Redente, H. Shelton Earp, Kristen M. Jacobsen, Anne M. Wofford, Karen E. Strunk, Deborah DeRyckere, Melissa Sandahl, Rebecca S. Cook, Jamie C. Stanford, Anne L. Prieto, Douglas K. Graham, Debra Hunter
MerTK, a receptor tyrosine kinase (RTK) of the TYRO3/AXL/MerTK family, is expressed in myeloid lineage cells in which it acts to suppress proinflammatory cytokines following ingestion of apoptotic material. Using syngeneic mouse models of breast canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0004759273e5f98bfc2b9b3f856d4c
Publikováno v:
Development. 122:1475-1488
Microsurgical, tissue grafting and in situ hybridization techniques have been used to investigate the role of the neural tube and notochord in the control of the myogenic bHLH genes, QmyoD, Qmyf5, Qmyogenin and the cardiac α-actin gene, during somit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ecec179ea6d2cb728df4d911d3272da
https://doi.org/10.1242/dev.122.5.1475
https://doi.org/10.1242/dev.122.5.1475
Autor:
Reade B. Roberts, Karen E. Strunk
Publikováno v:
genesis. 29:153-155
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d66cc5c269e7f0c305cdc19228835a8
https://doi.org/10.1002/gene.1018
https://doi.org/10.1002/gene.1018
Autor:
Karen E. Strunk, Carty Husted, Melissa Sandahl, Rebecca S. Muraoka-Cook, Leah C. Miraglia, Debra Hunter, H. Shelton Earp, Lewis A. Chodosh, Klaus Elenius
Publikováno v:
Molecular and cellular biology. 29(18)
Data concerning the prognostic value of ErbB4 in breast cancer and effects on cell growth have varied in published reports, perhaps due to the unknown signaling consequences of expression of the intracellular proteolytic ErbB4 s80(HER4) fragment or d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c312cb072e941d9856971f2e2fc51c39
https://pubmed.ncbi.nlm.nih.gov/19596786
https://pubmed.ncbi.nlm.nih.gov/19596786
Autor:
Rebecca S. Muraoka-Cook, Carty Husted, H. Shelton Earp, Debra Hunter, Melissa Sandahl, William A. Rearick, Leah C. Miraglia, Karen E. Strunk
Publikováno v:
Cancer research. 67(14)
Heregulin-mediated activation of HER4 initiates receptor cleavage (releasing an 80-kDa HER4 intracellular domain, s80HER4, containing nuclear localization sequences) and results in G2-M delay by unknown signaling mechanisms. We report herein that s80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aee6208472d71d17d999e36c40faae9
https://pubmed.ncbi.nlm.nih.gov/17638867
https://pubmed.ncbi.nlm.nih.gov/17638867
Autor:
H. Shelton Earp, Karen E. Strunk, Rebecca S. Muraoka-Cook, Wesley McCall, Kenneth H. Cowan, Magdalene K. Sgagias, Melissa Sandahl, Laura S. Caskey, Debra Hunter, Carty Husted, Carolyn I. Sartor, William A. Rearick
Publikováno v:
Molecular and cellular biology. 26(17)
HER4 expression in human breast cancers correlates with a positive prognosis. While heregulin inhibits the growth of HER4-positive breast cancer cells, it does so by undefined mechanisms. We demonstrate that heregulin-induced HER4 activity inhibits c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e66a8eaff848788ce54bbff7b54e45b
https://pubmed.ncbi.nlm.nih.gov/16914727
https://pubmed.ncbi.nlm.nih.gov/16914727
The timing of lethality caused by homozygosity for a null allele of the epidermal growth factor receptor (Egfrtm1Mag) in mice is strongly dependent on genetic background. Initial attempts to genetically map background modifiers using Swiss-derived, o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8f8d0c64b0bc4a9787ed6ca9102324
https://europepmc.org/articles/PMC1470975/
https://europepmc.org/articles/PMC1470975/