Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Karen E. O. Torres"'
Autor:
Deborah R Boone, Harris A Weisz, Hannah E Willey, Karen E O Torres, Michael T Falduto, Mala Sinha, Heidi Spratt, Ian J Bolding, Kathea M Johnson, Margaret A Parsley, Douglas S DeWitt, Donald S Prough, Helen L Hellmich
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214741 (2019)
There are no existing treatments for the long-term degenerative effects of traumatic brain injury (TBI). This is due, in part, to our limited understanding of chronic TBI and uncertainty about which proposed mechanisms for long-term neurodegeneration
Externí odkaz:
https://doaj.org/article/58771cd8849649299f0f75126e5daede
Autor:
Stacy L Sell, Deborah R Boone, Harris A Weisz, Cesar Cardenas, Hannah E Willey, Ian J Bolding, Maria-Adelaide Micci, Michael T Falduto, Karen E O Torres, Douglas S DeWitt, Donald S Prough, Helen L Hellmich
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221163 (2019)
Patients with traumatic brain injury (TBI) are frequently diagnosed with depression. Together, these two leading causes of death and disability significantly contribute to the global burden of healthcare costs. However, there are no drug treatments f
Externí odkaz:
https://doaj.org/article/754433036c8a46c394dae95ae3d62754
Autor:
Deborah R Boone, Jeanna M Leek, Michael T Falduto, Karen E O Torres, Stacy L Sell, Margaret A Parsley, Jeremy C Cowart, Tatsuo Uchida, Maria-Adelaide Micci, Douglas S DeWitt, Donald S Prough, Helen L Hellmich
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185943 (2017)
Virally mediated RNA interference (RNAi) to knock down injury-induced genes could improve functional outcome after traumatic brain injury (TBI); however, little is known about the consequences of gene knockdown on downstream cell signaling pathways a
Externí odkaz:
https://doaj.org/article/dcba9c0c5c804dfea3605fef84eb3953
Autor:
Perenlei Enkhbaatar, Christina Nelson, John R Salsbury, Joseph R Carmical, Karen E O Torres, David Herndon, Donald S Prough, Liming Luan, Edward R Sherwood
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144345 (2015)
Animal models that mimic human biology are important for successful translation of basic science discoveries into the clinical practice. Recent studies in rodents have demonstrated the efficacy of TLR4 agonists as immunomodulators in models of infect
Externí odkaz:
https://doaj.org/article/2c19cc975bf0431bb2d5beb3e19ee67e
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116285 (2015)
Oral squamous cell carcinomas (OSCC) induced in F344 rats by 4-nitroquinoline-1-oxide (4-NQO) demonstrate considerable phenotypic similarity to human oral cancers. Gene expression studies (microarray and PCR) were coupled with methylation analysis of
Externí odkaz:
https://doaj.org/article/eb931a60ff654244b84e606d9e5d4f07
Autor:
Rajendra G Mehta, Michael Hawthorne, Rajeshwari R Mehta, Karen E O Torres, Xinjian Peng, David L McCormick, Levy Kopelovich
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113175 (2014)
The present experiments were performed to determine the roles of estrogen receptors α and β (ERα and ERβ) in normal and neoplastic development in the mouse mammary gland. In wild-type mice, in vivo administration of estradiol (E) + progesterone (
Externí odkaz:
https://doaj.org/article/f6a1e2f7d1444543bd7e20b6d9243513
Autor:
Mala Sinha, Margaret A. Parsley, Karen E. O. Torres, Ian J. Bolding, Michael T. Falduto, Harris A. Weisz, Helen L. Hellmich, Hannah E. Willey, Donald S. Prough, Kathea M. Johnson, Douglas S. DeWitt, Deborah R. Boone, Heidi Spratt
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 4, p e0214741 (2019)
PLoS ONE, Vol 14, Iss 4, p e0214741 (2019)
There are no existing treatments for the long-term degenerative effects of traumatic brain injury (TBI). This is due, in part, to our limited understanding of chronic TBI and uncertainty about which proposed mechanisms for long-term neurodegeneration
Autor:
Ian J. Bolding, Deborah R. Boone, Michael T. Falduto, Maria-Adelaide Micci, Douglas S. DeWitt, Cesar Cardenas, Karen E. O. Torres, Harris A. Weisz, Hannah E. Willey, Donald S. Prough, Helen L. Hellmich, Stacy L. Sell
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221163 (2019)
PLoS ONE
PLoS ONE
Patients with traumatic brain injury (TBI) are frequently diagnosed with depression. Together, these two leading causes of death and disability significantly contribute to the global burden of healthcare costs. However, there are no drug treatments f
Autor:
Harris A. Weisz, Douglas S. DeWitt, Karen E. O. Torres, Hannah E. Willey, Donald S. Prough, Anjali M. Kumar, Min Bi, Helen L. Hellmich, Maria-Adelaide Micci, Christina M. Volsko, Deborah Kennedy Boone, Michael T. Falduto
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-3 (2018)
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
Autor:
Maria-Adelaide Micci, Karen E. O. Torres, Deborah Kennedy Boone, Douglas S. DeWitt, Anjali M. Kumar, Christina M. Volsko, Michael T. Falduto, Min Bi, Helen L. Hellmich, Hannah E. Willey, Donald S. Prough, Harris A. Weisz
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
The underlying molecular mechanisms of how dysregulated microRNAs (miRNAs) cause neurodegeneration after traumatic brain injury (TBI) remain elusive. Here we analyzed the biological roles of approximately 600 genes - we previously found these dysregu