Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Karen E. Livermore"'
Autor:
Jennifer Munkley, Urszula L. McClurg, Karen E. Livermore, Ingrid Ehrmann, Bridget Knight, Paul Mccullagh, John Mcgrath, Malcolm Crundwell, Lorna W. Harries, Hing Y. Leung, Ian G. Mills, Craig N. Robson, Prabhakar Rajan, David J. Elliott
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Cell migration drives cell invasion and metastatic progression in prostate cancer and is a major cause of mortality and morbidity. However the mechanisms driving cell migration in prostate cancer patients are not fully understood. We previou
Externí odkaz:
https://doaj.org/article/49dff917c9574813aafb665056c1069f
Autor:
Jennifer Munkley, Daniel Vodak, Karen E. Livermore, Katherine James, Brian T. Wilson, Bridget Knight, Paul Mccullagh, John Mcgrath, Malcolm Crundwell, Lorna W. Harries, Hing Y. Leung, Craig N. Robson, Ian G. Mills, Prabhakar Rajan, David J. Elliott
Publikováno v:
EBioMedicine, Vol 8, Iss C, Pp 103-116 (2016)
Steroid androgen hormones play a key role in the progression and treatment of prostate cancer, with androgen deprivation therapy being the first-line treatment used to control cancer growth. Here we apply a novel search strategy to identify androgen-
Externí odkaz:
https://doaj.org/article/bf075f00022b451c9d2a90e31147f783
Publikováno v:
AIMS Molecular Science, Vol 3, Iss 2, Pp 280-299 (2016)
Androgens play a key role in the development and progression of prostate cancer, and androgen deprivation therapy (ADT) is the first line treatment for advanced disease. Although ADT is initially successful in controlling prostate cancer, many patien
Externí odkaz:
https://doaj.org/article/2ea0f219afaa404896846847e1e8e1c1
Autor:
Jennifer Munkley, Teresa M. Maia, Nekane Ibarluzea, Karen E. Livermore, Daniel Vodak, Ingrid Ehrmann, Katherine James, Prabhakar Rajan, Nuno L. Barbosa-Morais, David J. Elliott
Publikováno v:
F1000Research, Vol 7 (2018)
Background: Androgen steroid hormones are key drivers of prostate cancer. Previous work has shown that androgens can drive the expression of alternative mRNA isoforms as well as transcriptional changes in prostate cancer cells. Yet to what extent and
Externí odkaz:
https://doaj.org/article/2bc77023a6054a83bbf4109346d9c6a2
Publikováno v:
Human Genetics
Changes in mRNA splice patterns have been associated with key pathological mechanisms in prostate cancer progression. The androgen receptor (abbreviated AR) transcription factor is a major driver of prostate cancer pathology and activated by androgen
Autor:
Bridget A. Knight, Nuno L. Barbosa-Morais, Mads Daugaard, Hanna A Zielinska, Ingrid Ehrmann, John J. McGrath, Oliver Thompson, Sebastian Oltean, Ling Li, Jennifer Munkley, Simon Cockell, Htoo Zarni Oo, Gerald Hysenaj, Lorna W. Harries, Kathleen Cheung, Emma Scott, David J. Elliott, Caroline Dalgliesh, Teresa Mendes Maia, S R Gokul Krishnan, Paul McCullagh, Karen E. Livermore, Malcolm Crundwell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c7d604f75a67bdac52cf6fde502c762
https://doi.org/10.7554/elife.47678.028
https://doi.org/10.7554/elife.47678.028
Publikováno v:
Oncology Letters.
Aberrant glycosylation is a universal feature of cancer cells and there is now overwhelming evidence that glycans can modulate pathways intrinsic to tumour cell biology. Glycans are important in all of the cancer hallmarks and there is a renewed inte
Autor:
Paul McCullagh, Emma Scott, David J. Elliott, Mads Daugaard, Oliver Thompson, John A. McGrath, Jennifer Munkley, Htoo Zarni Oo, Simon Cockell, Lorna W. Harries, Kathleen Cheung, Bridget A. Knight, Sebastian Oltean, Nuno L. Barbosa-Morais, Hanna A Zielinska, Karen E. Livermore, Gerald Hysenaj, Ingrid Ehrmann, Malcolm Crundwell, Teresa Mendes Maia, S R Gokul Krishnan, Ling Li
Prostate is the most frequent cancer in men. Prostate cancer progression is driven by androgen steroid hormones, and delayed by androgen deprivation therapy (ADT). Androgens control transcription by stimulating androgen receptor (AR) activity, yet al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0321ab6dd9c41d6bec34a9670e96dd88
https://doi.org/10.1101/629618
https://doi.org/10.1101/629618
Autor:
Jennifer, Munkley, Ling, Li, S R Gokul, Krishnan, Gerald, Hysenaj, Emma, Scott, Caroline, Dalgliesh, Htoo Zarni, Oo, Teresa Mendes, Maia, Kathleen, Cheung, Ingrid, Ehrmann, Karen E, Livermore, Hanna, Zielinska, Oliver, Thompson, Bridget, Knight, Paul, McCullagh, John, McGrath, Malcolm, Crundwell, Lorna W, Harries, Mads, Daugaard, Simon, Cockell, Nuno L, Barbosa-Morais, Sebastian, Oltean, David J, Elliott
Publikováno v:
eLife
Prostate is the most frequent cancer in men. Prostate cancer progression is driven by androgen steroid hormones, and delayed by androgen deprivation therapy (ADT). Androgens control transcription by stimulating androgen receptor (AR) activity, yet al
Autor:
Ian G. Mills, Bridget A. Knight, Karen E. Livermore, Urszula L. McClurg, Jennifer Munkley, Paul McCullagh, Lorna W. Harries, Hing Y. Leung, Katherine James, David J. Elliott, John J. McGrath, Prabhakar Rajan, Brian T. Wilson, Malcolm Crundwell, Sebastian Oltean, Craig N. Robson, Daniel Vodak
Publikováno v:
Endocrine Abstracts.