Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Karen E. Hayes"'
Autor:
Thomas R. Caulfield, Karen E. Hayes, Yushi Qiu, Mathew Coban, Joon Seok Oh, Amy L. Lane, Takehiko Yoshimitsu, Lori Hazlehurst, John A. Copland, Han W. Tun
Publikováno v:
Biomolecules, Vol 10, Iss 10, p 1407 (2020)
Chloroethylagelastatin A (CEAA) is an analogue of agelastatin A (AA), a natural alkaloid derived from a marine sponge. It is under development for therapeutic use against brain tumors as it has excellent central nervous system (CNS) penetration and p
Externí odkaz:
https://doaj.org/article/56d5687516d74c03a0f69d10c96b30fc
Autor:
Ivan Martinez, Patrick C. Ma, Gangqing Hu, Sijin Wen, Lin Zhu, Zuan-Fu Lim, Xiaoliang Wu, Erik A. Bey, Mackenzee Walker, Amanda S. Gatesman Ammer, Samuel A. Sprowls, Karen E. Hayes, Alana N. Stanley, Alyson M. Stevens, Michael T. Winters, Emily S. Westemeier, Brandon M. Harvey, Abby D. Ivey, Jamie A. Juric, Tayvia Brownmiller
Table S1 to S4; Figures S1 to S12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e7a073cea00e4697943b3fc0cd8bc6
https://doi.org/10.1158/0008-5472.22425486
https://doi.org/10.1158/0008-5472.22425486
Autor:
Ivan Martinez, Xiaoliang Wu, Samuel A. Sprowls, Emily S. Westemeier, Jamie A. Juric, Sijin Wen, Erik A. Bey, Michael T. Winters, Karen E. Hayes, Amanda S. Gatesman Ammer, Alyson M. Stevens, Mackenzee Walker, Abby D. Ivey, Patrick C. Ma, Tayvia Brownmiller, Zuan Fu Lim, Brandon M. Harvey, Alana N. Stanley, Gangqing Hu, Lin Zhu
Publikováno v:
Cancer Res
Numerous studies have implicated changes in the Y chromosome in male cancers, yet few have investigated the biological importance of Y chromosome noncoding RNA. Here we identify a group of Y chromosome–expressed long noncoding RNA (lncRNA) that are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931f307c25e99095bae752ca171d85c8
https://doi.org/10.1158/0008-5472.can-19-4032
https://doi.org/10.1158/0008-5472.can-19-4032
Autor:
Lori A. Hazlehurst, Karen E. Hayes, Yushi Qiu, Han W. Tun, Amy L. Lane, Takehiko Yoshimitsu, Joon Seok Oh, Thomas R. Caulfield, Mathew A. Coban, John A. Copland
Publikováno v:
Biomolecules
Volume 10
Issue 10
Biomolecules, Vol 10, Iss 1407, p 1407 (2020)
Volume 10
Issue 10
Biomolecules, Vol 10, Iss 1407, p 1407 (2020)
Chloroethylagelastatin A (CEAA) is an analogue of agelastatin A (AA), a natural alkaloid derived from a marine sponge. It is under development for therapeutic use against brain tumors as it has excellent central nervous system (CNS) penetration and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5066c91d81e47f0013cd426384ccc7c4
Autor:
Rajaganapathi Jagannathan, Abby D. Harold, Karen E. Hayes, Ivan Martinez, Saleem A. Khan, Jamie A. Barr, Paul R. Lockman, Tayvia Brownmiller
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
High-risk human papillomavirus (HPV) infection is one of the first events in the process of carcinogenesis in cervical and head and neck cancers. The expression of the viral oncoproteins E6 and E7 are essential in this process by inactivating the tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e1fb63aed086a9ab665a1127217847
https://doi.org/10.1038/s41598-019-40094-8
https://doi.org/10.1038/s41598-019-40094-8
Autor:
Werner J. Geldenhuys, Karen E. Hayes, Steven A. Eschrich, Yan Yang, Andreas Becker, Aaron R. Robart, Wei-Chih Chen, Lori A. Hazlehurst, Paratchata Batsomboon, Gregory B. Dudley, Brennan D. Johnson
Multiple myeloma (MM) cells demonstrate high basal endoplasmic reticulum (ER) stress and are typically exquisitely sensitive to agents such as proteasome inhibitors that activate the unfolded protein response. The flavin adenosine dinucleotide (FAD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08765e16f632d90564a1ef873bdb38bb
https://europepmc.org/articles/PMC6554731/
https://europepmc.org/articles/PMC6554731/
Publikováno v:
Molecular Cancer Therapeutics. 18:A019-A019
Introduction: Multiple Myeloma (MM) is a hematologic cancer characterized by neoplastic proliferation of the plasma cells in the bone marrow. Newly diagnosed MM patients typically respond to currently available treatments. However, the disease is not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb1212eba21c4c552a5fa0c9f1360b4b
https://doi.org/10.1158/1535-7163.targ-19-a019
https://doi.org/10.1158/1535-7163.targ-19-a019
Publikováno v:
BIO-PROTOCOL. 8
Cellular quiescence (also known as G0 arrest) is characterized by reduced DNA replication, increased autophagy, and increased expression of cyclin-dependent kinase p27Kip1. Quiescence is essential for wound healing, organ regeneration, and preventing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d6484da91b852120a623954b632722
https://doi.org/10.21769/bioprotoc.2717
https://doi.org/10.21769/bioprotoc.2717
Autor:
Shobha Vasudevan, Karen E. Hayes, Daniel DiMaio, Joan A. Steitz, Ivan Martinez, Abby D. Harold, Jamie A. Barr, Syed I. A. Bukhari, Mingyi Xie
The reversible state of proliferative arrest known as “cellular quiescence” plays an important role in tissue homeostasis and stem cell biology. By analyzing the expression of miRNAs and miRNA-processing factors during quiescence in primary human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa98c998d002ec16ff13a4de252dbd2
https://europepmc.org/articles/PMC5488920/
https://europepmc.org/articles/PMC5488920/