Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Karen E. Bowker"'
Publikováno v:
Journal of Antimicrobial Chemotherapy. 76:1840-1844
Background Tetracyclines are widely used as oral therapy of MRSA infection, however, the pharmacodynamic underpinning is absent. Objectives We employed an in vitro pharmacokinetic model to study the pharmacodynamics of minocycline alone and in combin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096a01f4555d702bbf5a5244f1124bc4
https://doi.org/10.1093/jac/dkab112
https://doi.org/10.1093/jac/dkab112
Publikováno v:
Journal of Antimicrobial Chemotherapy. 76:667-670
Background The pharmacodynamics of omadacycline have been extensively studied against Gram-positive pathogens but less information is available for Gram-negative pathogens. We describe the pre-clinical pharmacodynamics of omadacycline against Escheri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5684c98ce1fe550f353404cb7fd43ebc
https://doi.org/10.1093/jac/dkaa508
https://doi.org/10.1093/jac/dkaa508
Publikováno v:
The Journal of antimicrobial chemotherapy. 77(5)
Background There is surprisingly little comparative published data on the bactericidal action of different sub-classes of β-lactams against aerobic Gram-negative rods, and the assumption is that all behave in the same way. Objectives To describe a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f8c4b491b314dd4a37db9bf71a6f77
https://pubmed.ncbi.nlm.nih.gov/35137096
https://pubmed.ncbi.nlm.nih.gov/35137096
Autor:
Jing Chai, Jilu Shen, Isabel Oliver, Debing Wang, Jing Cheng, Helen Lambert, Karen E. Bowker, Xingrong Shen, Yaping Pan, Alasdair P. MacGowan
Publikováno v:
Shen, X, MacGowan, A, Oliver, I, Lambert, H, Wang, D & al., E 2021, ' Clinical diagnosis and treatment of common respiratory tract infections in relation to microbiological profiles in rural health facilities in China : implications for antibiotic stewardship ', BMC Family Practice, vol. 22, no. 1, 87 . https://doi.org/10.1186/s12875-021-01448-2
BMC Family Practice, Vol 22, Iss 1, Pp 1-9 (2021)
BMC Family Practice
BMC Family Practice, Vol 22, Iss 1, Pp 1-9 (2021)
BMC Family Practice
BackgroundThis paper tries to describe prevalence and patterns of antibiotics prescription and bacteria detection and sensitivity to antibiotics in rural China and implications for future antibiotic stewardship.MethodsThe study was implemented in one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aff7f09ba8ca04694f6a281f6a2f553
https://research-information.bris.ac.uk/ws/files/280065138/s12875_021_01448_2.pdf
https://research-information.bris.ac.uk/ws/files/280065138/s12875_021_01448_2.pdf
Autor:
Oliver Mounsey, Katy Morley, Emma F. Puddy, Katy Turner, Hannah Schubert, Philip B Williams, Virginia C. Gould, Karen E. Bowker, Paul North, Matthew B. Avison, O. Martin Williams, David C Barrett, Kristen K. Reyher, Tristan A Cogan, Alasdair P. MacGowan, Jacqueline Findlay
Publikováno v:
Journal of Antimicrobial Chemotherapy
Mounsey, O J, Schubert, H, Findlay, J, Morley, C, Puddy, E F, Gould, V C, North, P, Bowker, K E, Williams, O M, Williams, P B, Barrett, D C, Cogan, T A, Turner, K M E, MacGowan, A P, Reyher, K K & Avison, M B 2021, ' Limited phylogenetic overlap between fluoroquinolone-resistant Escherichia coli isolated on dairy farms and those causing bacteriuria in humans living in the same geographical region ', Journal of Antimicrobial Chemotherapy, vol. 76, no. 12, pp. 3144–3150 . https://doi.org/10.1093/jac/dkab310
Mounsey, O J, Schubert, H, Findlay, J, Morley, C, Puddy, E F, Gould, V C, North, P, Bowker, K E, Williams, O M, Williams, P B, Barrett, D C, Cogan, T A, Turner, K M E, MacGowan, A P, Reyher, K K & Avison, M B 2021, ' Limited phylogenetic overlap between fluoroquinolone-resistant Escherichia coli isolated on dairy farms and those causing bacteriuria in humans living in the same geographical region ', Journal of Antimicrobial Chemotherapy, vol. 76, no. 12, pp. 3144–3150 . https://doi.org/10.1093/jac/dkab310
SynopsisBackgroundOur primary aim was to test whether cattle-associated fluoroquinolone-resistant (FQ-R) Escherichia coli found on dairy farms were a significant cause of bacteriuria in humans living in the same 50 × 50 km geographical region locate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85998a7cac8b8a8d69599b786385fdd2
https://pubmed.ncbi.nlm.nih.gov/34450630
https://pubmed.ncbi.nlm.nih.gov/34450630
Autor:
Jing Chai, Yaping Pan, Alasdair P. MacGowan, Karen E. Bowker, Rachel Kwiatkowska, Isabel Oliver, Paul Kadetz, Matthew Hickman, Meixuan Chen, Rui Feng, Jilu Shen, Linhai Zhao, Helen Lambert, Xin-Rong Shen, Christie Cabral, Jing Cheng, Xiaowen Hu, Debin Wang
Background: We tested the feasibility of determining the prevalence and epidemiology of antibiotic resistance in rural China and investigated patterns and drivers of antibiotic use for common respiratory and urinary tract infections (RTI/UTI). Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8515ae16d29f560d92ff4fae597d8e29
https://doi.org/10.21203/rs.3.rs-249016/v1
https://doi.org/10.21203/rs.3.rs-249016/v1
Publikováno v:
International journal of antimicrobial agents. 56(1)
Objectives The pharmacodynamics of intravenous fosfomycin have not been described for Gram-positive pathogens such as Staphylococcus aureus (S. aureus). This paper described the dominant pharmacodynamic index for fosfomycin against S. aureus and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097b57dd18baa568040c046fc6d28904
https://pubmed.ncbi.nlm.nih.gov/32330585
https://pubmed.ncbi.nlm.nih.gov/32330585
Autor:
Virginia C. Gould, Alasdair P. MacGowan, Jacqueline Findlay, O. Martin Williams, Paul North, Matthew B. Avison, Karen E. Bowker
Publikováno v:
Findlay, J, Gould, V C, North, P, Bowker, K E, Williams, M, MacGowan, A P & Avison, M B 2020, ' Characterization of cefotaxime-resistant urinary Escherichia coli from primary care in South-West England 2017-18 ', The Journal of antimicrobial chemotherapy, vol. 75, no. 1, pp. 65–71 . https://doi.org/10.1093/jac/dkz397
Objectives Third-generation cephalosporin-resistant Escherichia coli from community-acquired urinary tract infections are increasingly reported worldwide. We sought to determine and characterize the mechanisms of cefotaxime resistance employed by uri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5868cbadc4a1e39de6c870333797686
https://research-information.bris.ac.uk/en/publications/294529c1-22e0-4e71-bc2d-995786e0ab81
https://research-information.bris.ac.uk/en/publications/294529c1-22e0-4e71-bc2d-995786e0ab81
Publikováno v:
The Journal of antimicrobial chemotherapy. 75(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d19a2a8fb0d0b0a9304d57180e07a97
https://pubmed.ncbi.nlm.nih.gov/31848597
https://pubmed.ncbi.nlm.nih.gov/31848597
Publikováno v:
Journal of Antimicrobial Chemotherapy. 75:2711-2712
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632dac01f740fcdad63c3d954c9eb109
https://doi.org/10.1093/jac/dkaa177
https://doi.org/10.1093/jac/dkaa177