Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Karen E Isherwood"'
Autor:
Roy R Chaudhuri, Chuan-Peng Ren, Leah Desmond, Gemma A Vincent, Nigel J Silman, John K Brehm, Michael J Elmore, Michael J Hudson, Mats Forsman, Karen E Isherwood, Darina Gurycová, Nigel P Minton, Richard W Titball, Mark J Pallen, Richard Vipond
Publikováno v:
PLoS ONE, Vol 2, Iss 4, p e352 (2007)
Francisella tularensis causes tularaemia, a life-threatening zoonosis, and has potential as a biowarfare agent. F. tularensis subsp. tularensis, which causes the most severe form of tularaemia, is usually confined to North America. However, a handful
Externí odkaz:
https://doaj.org/article/7d7727c30237431bb987dadb59550f21
Publikováno v:
Advanced Drug Delivery Reviews. 57:1403-1414
Francisella tularensis is the etiologic agent of tularemia, a severe debilitating disease of humans and animals. The low infectious dose of F. tularensis in humans and the relative ease of culture are probably the properties which originally attracte
Autor:
Karen E. Isherwood, Petra C. F. Oyston
Publikováno v:
Antonie van Leeuwenhoek. 87:171-177
Yersinia pestis, the causative agent of bubonic and pneumonic plague, has a complex lifestyle, cycling between both arthropod and mammalian hosts. This pathogen has previously been shown to survive intracellularly within macrophages and to be capable
Autor:
Greger Hälltorp, May C. Chu, Brendan W. Wren, Luther E. Lindler, Peter D. Karp, Emilio Garcia, Hans-Henrik Fuxelius, Kerstin Svensson, Mats Forsman, Richard G. Prior, Anders Sjöstedt, Stephanie Malfatti, Lisa M. Vergez, Patrick S. G. Chain, Pär Larsson, Melanie Duffield, Siv G. E. Andersson, Nicholas R Thompson, Ying Liu, Eva Larsson, Jonathan Wagg, Richard W. Titball, Karen E. Isherwood, Petra C. F. Oyston, Daniel Johansson, Stephen L. Michell, Joann L. Prior
Publikováno v:
Nature Genetics. 37:153-159
Francisella tularensis is one of the most infectious human pathogens known. In the past, both the former Soviet Union and the US had programs to develop weapons containing the bacterium. We report the complete genome sequence of a highly virulent iso
Autor:
B. Joseph Hinnebusch, Scott D. Kobayashi, Clayton O. Jarrett, Eszter Deak, Adeline R. Whitney, Karen E. Isherwood, Frank R. DeLeo, Elizabeth R. Fischer, Petra C. F. Oyston
Publikováno v:
The Journal of Infectious Diseases. 190:783-792
Transmission of plague by fleas depends on infection of the proventricular valve in the insect's foregut by a dense aggregate of Yersinia pestis. Proventricular infection requires the Y. pestis hemin storage (hms) genes; here, we show that the hms ge
Autor:
Richard W. Titball, Brendan N. Neeson, Anders Johansson, Rebecca M. Thomas, Anders Sjöstedt, Jill Ellis, Karen E. Isherwood
Publikováno v:
Journal of Clinical Microbiology. 41:50-57
We describe the use of two insertion sequence elements (ISFtu1 and ISFtu2) in Francisella tularensis to type strains by restriction fragment length polymorphism (RFLP). The RFLP profiles of 17 epidemiologically unrelated isolates were determined and
Autor:
Michael J. Hudson, Michael J. Elmore, Mats Forsman, Nigel Silman, Roy R. Chaudhuri, Richard Vipond, Leah Desmond, Richard W. Titball, John K. Brehm, Darina Guryčová, Mark J. Pallen, Chuan-Peng Ren, Gemma A. Vincent, Nigel P. Minton, Karen E. Isherwood
Publikováno v:
PLoS ONE, Vol 2, Iss 4, p e352 (2007)
PLoS ONE
PLoS ONE
Background Francisella tularensis causes tularaemia, a life-threatening zoonosis, and has potential as a biowarfare agent. F. tularensis subsp. tularensis, which causes the most severe form of tularaemia, is usually confined to North America. However
Autor:
J.E. Quarry, Richard W. Titball, Stephen L. Michell, Karen E. Isherwood, Petra C. F. Oyston, Helen Diaper
Publikováno v:
Vaccine. 25(11)
Francisella tularensis subspecies novicida mutants have been made with deletions introduced into the purA or purF genes. These mutants demonstrated the expected growth requirement for purines and complementation with the wild type genes restored the
Autor:
Adam A. Witney, Michael B. Prentice, Brendan W. Wren, Richard A. Stabler, Karen E. Isherwood, Petra C. F. Oyston, Phillip D. Butcher, Richard W. Titball, Jason Hinds, Stewart J. Hinchliffe, Joseph A. Mangan
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9780306477591
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::133de85167ff051a0fbac6d95c277c9f
https://doi.org/10.1007/0-306-48416-1_9
https://doi.org/10.1007/0-306-48416-1_9
Autor:
Alexander Rakin, Richard A. Nichols, Richard A. Stabler, Jason Hinds, Michael B. Prentice, Richard W. Titball, Stewart J. Hinchliffe, Karen E. Isherwood, Petra C. F. Oyston, Brendan W. Wren
Publikováno v:
Genome research. 13(9)
Yersinia pestis, the causative agent of plague, diverged from Yersinia pseudotuberculosis, an enteric pathogen, an estimated 1500–20,000 years ago. Genetic characterization of these closely related organisms represents a useful model to study the r