Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Karen Dockstader"'
Autor:
Edward Lau, Anis Karimpour-Fard, Karen Dockstader, Danielle A. Jeffrey, Julie Pires Da Silva, Michael R. Bristow, Carmen C. Sucharov, Kathleen C. Woulfe, Brian L. Stauffer, Jennifer H. Mahaffey, Frehiwet Hailu, Shelley D. Miyamoto, Cortney E. Wilson, Dobromir Slavov
Publikováno v:
J Mol Cell Cardiol
Aims Pediatric dilated cardiomyopathy (pDCM) is characterized by unique age-dependent molecular mechanisms that include myocellular responses to therapy. We previously showed that pDCM, but not adult DCM patients respond to phosphodiesterase 3 inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9990f60608a6d8bc17bd7ec4657badff
https://doi.org/10.1016/j.yjmcc.2021.06.007
https://doi.org/10.1016/j.yjmcc.2021.06.007
Autor:
Karen Dockstader, Ryan Mansfield, Qitong Yuan, Courtney L Olbrich, Maytal Bivas-Benita, Samuel Maldonado, Jason J. Xenakis, Julia Fink, Evangeline W. Cornwell, Lisa A. Spencer, Nathan Gill
Publikováno v:
Mucosal Immunology. 13:777-787
The natural history of allergic diseases suggests bidirectional and progressive relationships between allergic disorders of the skin, lung, and gut indicative of mucosal organ crosstalk. However, impacts of local allergic inflammation on the cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa1953d40ec8e88e3d5195ebb0941a26
https://doi.org/10.1038/s41385-020-0310-x
https://doi.org/10.1038/s41385-020-0310-x
Publikováno v:
Journal of leukocyte biologyREFERENCES. 111(5)
Intestinal eosinophils are implicated in the inflammatory pathology of eosinophilic gastrointestinal diseases and inflammatory bowel diseases. Eosinophils also contribute to intestinal immunologic and tissue homeostasis and host defense. Recent studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067c5c672606c0244989b4dbfe9b5d60
https://pubmed.ncbi.nlm.nih.gov/35132683
https://pubmed.ncbi.nlm.nih.gov/35132683
Publikováno v:
Journal of Biological Chemistry. 293:3126-3133
A glutamate-to-lysine substitution at position 1014 within the selectivity filter of the skeletal muscle L-type Ca(2+) channel (Ca(V)1.1) abolishes Ca(2+) flux through the channel pore. Mice engineered to exclusively express the mutant channel displa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a20f975b045b3c2b531a7eca3c5c36b
https://doi.org/10.1074/jbc.m117.812446
https://doi.org/10.1074/jbc.m117.812446
Autor:
Courtney L, Olbrich, Maytal, Bivas-Benita, Jason J, Xenakis, Samuel, Maldonado, Evangeline, Cornwell, Julia, Fink, Qitong, Yuan, Nathan, Gill, Ryan, Mansfield, Karen, Dockstader, Lisa A, Spencer
Publikováno v:
Mucosal Immunology
The natural history of allergic diseases suggests bidirectional and progressive relationships between allergic disorders of the skin, lung, and gut indicative of mucosal organ crosstalk. However, impacts of local allergic inflammation on the cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f3e4d2191516529b5147462ea25b9bd2
https://pubmed.ncbi.nlm.nih.gov/32719410
https://pubmed.ncbi.nlm.nih.gov/32719410
Autor:
Michael R. Bristow, Stephen B. Liggett, Karen Dockstader, Penny Nelson, Allen Medway, Carmen C. Sucharov, J. David Port, Anis Karimpour-Fard, Karin Nunley
Publikováno v:
Physiological Genomics. 43:1294-1306
Several studies in humans or transgenic animals have reported that the 389 Arg or Gly polymorphic variation of the β1-adrenergic receptor (AR) is associated with differential responses to beta-blocker therapy and/or myocardial disease progression. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad1de60c0308e8e2889a99c81df5668
https://doi.org/10.1152/physiolgenomics.00067.2011
https://doi.org/10.1152/physiolgenomics.00067.2011
Publikováno v:
Journal of Cardiac Failure. 17:592-600
Introduction Chronic activation of β 1 -adrenergic receptor (β 1 -AR) signaling can have deleterious effects on the heart, and animal models overexpressing β 1 -ARs develop a dilated cardiomyopathy and heart failure. In the classic β-AR pathway,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451e11706a28d1a5cb74940b20f16241
https://doi.org/10.1016/j.cardfail.2011.03.006
https://doi.org/10.1016/j.cardfail.2011.03.006
Publikováno v:
Molecular Biology of the Cell. 19:4141-4153
YY1 is a transcription factor that can repress or activate the transcription of a variety of genes. Here, we show that the function of YY1 as a repressor in cardiac myocytes is tightly dependent on its ability to interact with histone deacetylase 5 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd8093e001433ae6a855b14061af504
https://doi.org/10.1091/mbc.e07-12-1217
https://doi.org/10.1091/mbc.e07-12-1217
Autor:
Lori J. Silveira, Anna L. Lagan, Richard T. Sawyer, Kenneth I. Welsh, P. A. Lympany, Tasha E. Fingerlin, Karen Dockstader, Roland M. du Bois, Lisa A. Maier, May Gillespie, Hiroe Sato
Publikováno v:
Journal of Allergy and Clinical Immunology. 119:687-696
Background Beryllium stimulates TNF-α from chronic beryllium disease (CBD) bronchoalveolar lavage (BAL) cells. Objective We sought to relate TNF polymorphisms to beryllium-stimulated TNF-α production, to the development of CBD, and to the risk of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7cded9c6b389029e7c15822f150b04
https://doi.org/10.1016/j.jaci.2006.10.028
https://doi.org/10.1016/j.jaci.2006.10.028
Autor:
Allen Medway, Karen Dockstader, Carmen C. Sucharov, Gloria Russell, Mackenzie Cecil, Timothy A. McKinsey, Kimberly M. Demos-Davies, Brian L. Stauffer, Jamie G. Hijmans, Lisa Walker
Publikováno v:
Biochemical and biophysical research communications. 462(2)
YY1 can activate or repress transcription of various genes. In cardiac myocytes in culture YY1 has been shown to regulate expression of several genes involved in myocyte pathology. YY1 can also acutely protect the heart against detrimental changes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9cc82ae329624a1ce691c4e940e19dd
https://pubmed.ncbi.nlm.nih.gov/25935483
https://pubmed.ncbi.nlm.nih.gov/25935483