Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Karen Dahlke"'
Autor:
Bernd Jahrsdörfer, Hubert Schrezenmeier, Peter Möller, Rolf Kreienberg, Thomas Simmet, G. Ulrich Nienhaus, Oleg Lunov, Ramin Lotfi, Dorit Fabricius, Frank Reister, Thamara Beyer, Thomas F.E. Barth, Christof Kaltenmeier, Magdalena Hagn, Kai Sontheimer, Karen Dahlke, Stefanie Lindner
PDF file - 182K, Supplemental Figure 1. B cells activated with IL-21 and anti-BCR secrete enzymatically active granzyme B. Supplemental Figure 2. Interleukin 21 in the absence of B cells does not suppress T cell proliferation. Supplemental Figure 3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e0bf137b5ad341824f146517ce1bf2
https://doi.org/10.1158/0008-5472.22399989.v1
https://doi.org/10.1158/0008-5472.22399989.v1
Autor:
Thamara Beyer, Thomas F. E. Barth, Dorit Fabricius, Ramin Lotfi, Kai Sontheimer, Karen Dahlke, Frank Reister, Gerd Ulrich Nienhaus, Peter Möller, Thomas Simmet, Bernd Jahrsdörfer, Rolf Kreienberg, Oleg Lunov, Magdalena Hagn, Stefanie Lindner, Christof Kaltenmeier, Hubert Schrezenmeier
Publikováno v:
Cancer Research. 73:2468-2479
The pathogenic impact of tumor-infiltrating B cells is unresolved at present, however, some studies suggest that they may have immune regulatory potential. Here, we report that the microenvironment of various solid tumors includes B cells that expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b665f18c2c45560993dd9ee2405bd8bd
https://doi.org/10.1158/0008-5472.can-12-3450
https://doi.org/10.1158/0008-5472.can-12-3450
Autor:
Oleg Lunov, G. Ulrich Nienhaus, Karen Dahlke, Dorit Fabricius, Bernd Jahrsdörfer, Thomas Simmet, Magdalena Hagn, Kai Sontheimer, Thamara Beyer, Kyrylo Tron
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e97212c30fa141a9771c532b07424e92
https://doi.org/10.1096/fasebj.24.1_supplement.lb506
https://doi.org/10.1096/fasebj.24.1_supplement.lb506
Autor:
Thomas Simmet, Thamara Beyer, Kyrylo Tron, Karen Dahlke, Kai Sontheimer, Magdalena Hagn, Oleg Lunov, G. Ulrich Nienhaus, Bernd Jahrsdoerfer, Dorit Fabricius
Publikováno v:
The FASEB Journal. 24
Abstract 3905 Immune regulation is central for the development of an efficient cellular immune response. Both Treg cells and plasmacytoid DC can suppress T cell proliferation in a granzyme B (GzmB)-dependent and perforin-independent manner. In the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df44a2f8a63c8456092af6333321deff
https://doi.org/10.1096/fasebj.24.1_supplement.lb507
https://doi.org/10.1096/fasebj.24.1_supplement.lb507
Autor:
Ramin Lotfi, Magdalena Hagn, Dorit Fabricius, Bernd Jahrsdörfer, Oleg Lunov, Stefanie Lindner, Thamara Beyer, Christof Kaltenmeier, Ulrich Nienhaus, Hubert Schrezenmeier, Rolf Kreienberg, Peter Moeller, Karen Dahlke, Kai Sontheimer, Frank Reister, Thomas Simmet, Thomas F. E. Barth
Publikováno v:
Blood. 120:3278-3278
Abstract 3278 The role of B cells in tumor infiltrations is controversial. Different studies suggest that certain tumor-infiltrating B cell populations exhibit regulatory potential. Here, we demonstrate that the microenvironment of various solid tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::809f9268c485fb0fabacebd2f778f204
https://doi.org/10.1182/blood.v120.21.3278.3278
https://doi.org/10.1182/blood.v120.21.3278.3278
Autor:
Christof Kaltenmeier, Karen Dahlke, Ali Gawanbacht, Stefanie Hofmann, Thamara Beyer, Georg Härter, Beate Grüner, Peter Kern, Frank Kirchhoff, Hubert Schrezenmeier, Bernd Jahrsdörfer
Publikováno v:
The Journal of Immunology. 188:105.18-105.18
Certain lymphocyte subsets including plasmacytoid dendritic cells and regulatory T cells can secrete granzyme B (GrB), thereby suppressing T cell expansion. Recently, we found that B cells can also produce GrB in response to interleukin (IL) 21. Sinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::966d5447ad18ce5f927b3dd3a1b3f02f
https://doi.org/10.4049/jimmunol.188.supp.105.18
https://doi.org/10.4049/jimmunol.188.supp.105.18
Autor:
Ali Gawanbacht, Peter Kern, Hubert Schrezenmeier, Beate Grüner, Thamara Beyer, Christof Kaltenmeier, S Hofmann, Georg Härter, Bernd Jahrsdörfer, Karen Dahlke, Frank Kirchhoff
Publikováno v:
Web of Science
Abstract 3222 We and others have recently provided evidence that a series of lymphocyte subsets including, plasmacytoid dendritic cells, B cells and regulatory T cells are able to secrete the cytotoxic serine protease granzyme B (GrB) into the extrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4a45f198008844865b8eb831f6c684
https://doi.org/10.1182/blood.v118.21.3222.3222
https://doi.org/10.1182/blood.v118.21.3222.3222
Autor:
Thamara Beyer, Bernd Jahrsdoerfer, George J. Weiner, Karen Dahlke, Magdalena Hagn, Sue E. Blackwell, Verena Ebel, Kai Sontheimer, Thomas Simmet
Publikováno v:
Blood. 116:3906-3906
Abstract 3906 Interleukin 21 (IL-21) and CpG oligodeoxynucleotides (CpG ODN) are two novel and highly promising agents for the treatment of hematological diseases. Recently, we reported that IL-21 and CpG ODN induce granzyme B (GrB) and GrB-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::276ced1ac5d14ad82b857034958ef93d
https://doi.org/10.1182/blood.v116.21.3906.3906
https://doi.org/10.1182/blood.v116.21.3906.3906