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pro vyhledávání: '"Karen D. Jack"'
Publikováno v:
Chemical Biology & Drug Design. 79:202-208
The T box antiterminator RNA element is an important component of the T box riboswitch that controls the transcription of vital genes in many Gram-positive bacteria. A series of 1,4-disubstituted 1,2,3-triazoles was screened in a fluorescence-monitor
Publikováno v:
Biochemical and Biophysical Research Communications. 370:306-310
T box bacterial genes utilize a riboswitch mechanism to regulate gene expression at the transcriptional level. Complementary base pairing of the 5′-untranslated mRNA with uncharged cognate tRNA stabilizes formation of an antiterminator element and
Publikováno v:
Nucleic Acids Research
The T box transcription antitermination regulatory system, found in Gram-positive bacteria, is dependent on a complex set of interactions between uncharged tRNA and the 5′-untranslated mRNA leader region of the regulated gene. One of these interact