Reduced brain connectivity underlying value-based choices and outcomes in stimulant use disorder

Autor: Liam J. Nestor, Tsen Vei Lim, Trevor W. Robbins, Karen D. Ersche

Publikováno v: NeuroImage: Clinical, Vol 44, Iss , Pp 103676- (2024)

BACKGROUND: Patients with stimulant use disorder (SUD) show impairments when making value-based choices that are associated with disruptions in neural processing across brain networks. Making optimal choices requires learning from outcomes to update

Externí odkaz: https://doaj.org/article/d65bea0700f6460996deb46713a3f178

Selective D3 receptor antagonism modulates neural response during negative emotional processing in substance dependence

Autor: Ioanna A. Vamvakopoulou, Leon Fonville, Alexandra Hayes, John McGonigle, Rebecca Elliott, Karen D. Ersche, Remy Flechais, Csaba Orban, Anna Murphy, Dana G. Smith, John Suckling, Eleanor M. Taylor, Bill Deakin, Trevor W. Robbins, David J. Nutt, Anne R. Lingford-Hughes, Louise M. Paterson

Publikováno v: Frontiers in Psychiatry, Vol 13 (2022)

IntroductionNegative affective states contribute to the chronic-relapsing nature of addiction. Mesolimbic dopamine D3 receptors are well placed to modulate emotion and are dysregulated in substance dependence. Selective antagonists might restore dopa

Externí odkaz: https://doaj.org/article/4e8eb72042e4416497f16af44766cb8c

Drug Use in Night Owls May Increase the Risk for Mental Health Problems

Autor: Jeevan Fernando, Jan Stochl, Karen D. Ersche

Publikováno v: Frontiers in Neuroscience, Vol 15 (2022)

Drugs of abuse are widely known to worsen mental health problems, but this relationship may not be a simple causational one. Whether or not a person is susceptible to the negative effects of drugs of abuse may not only be determined by their addictiv

Externí odkaz: https://doaj.org/article/c8a9af81c82047ab8f7032cba1e42e83

Disturbances across whole brain networks during reward anticipation in an abstinent addiction population

Autor: Liam J. Nestor, John Suckling, Karen D. Ersche, Anna Murphy, John McGonigle, Csaba Orban, Louise M. Paterson, Laurence Reed, Eleanor Taylor, Remy Flechais, Dana Smith, Edward T. Bullmore, Rebecca Elliott, Bill Deakin, Ilan Rabiner, Anne-Lingford Hughes, Barbara J. Sahakian, Trevor W. Robbins, David J. Nutt

Publikováno v: NeuroImage: Clinical, Vol 27, Iss , Pp 102297- (2020)

The prevalent spatial distribution of abnormalities reported in cognitive fMRI studies in addiction suggests there are extensive disruptions across whole brain networks. Studies using resting state have reported disruptions in network connectivity in

Externí odkaz: https://doaj.org/article/9987c11e6b0d4de496ea949fe410a846

Cognitive training and remediation interventions for substance use disorders: a Delphi consensus study

Autor: Antonio Verdejo‐Garcia, Tara Rezapour, Emily Giddens, Arash Khojasteh Zonoozi, Parnian Rafei, Jamie Berry, Alfonso Caracuel, Marc L. Copersino, Matt Field, Eric L. Garland, Valentina Lorenzetti, Leandro Malloy‐Diniz, Victoria Manning, Ely M. Marceau, David L. Pennington, Justin C. Strickland, Reinout Wiers, Rahia Fairhead, Alexandra Anderson, Morris Bell, Wouter J. Boendermaker, Samantha Brooks, Raimondo Bruno, Salvatore Campanella, Janna Cousijn, W. Miles Cox, Andrew C. Dean, Karen D. Ersche, Ingmar Franken, Brett Froeliger, Pedro Gamito, Thomas E. Gladwin, Priscila D. Goncalves, Katrijn Houben, Joanna Jacobus, Andrew Jones, Anne M. Kaag, Johannes Lindenmeyer, Elly McGrath, Talia Nardo, Jorge Oliveira, Charlotte R. Pennington, Kelsey Perrykkad, Hugh Piercy, Claudia I. Rupp, Mieke H. J. Schulte, Lindsay M. Squeglia, Petra Staiger, Dan J. Stein, Jeff Stein, Maria Stein, William W. Stoops, Mary Sweeney, Katie Witkiewitz, Steven P. Woods, Richard Yi, Min Zhao, Hamed Ekhtiari

Publikováno v: Addiction, 118, 935-951. Wiley
Verdejo-Garcia, A, Rezapour, T, Giddens, E, Khojasteh Zonoozi, A, Rafei, P, Berry, J, Caracuel, A, Copersino, M L, Field, M, Garland, E L, Lorenzetti, V, Malloy-Diniz, L, Manning, V, Marceau, E M, Pennington, D L, Strickland, J C, Wiers, R, Fairhead, R, Anderson, A, Bell, M, Boendermaker, W J, Brooks, S, Bruno, R, Campanella, S, Cousijn, J, Cox, W M, Dean, A C, Ersche, K D, Franken, I, Froeliger, B, Gamito, P, Gladwin, T E, Goncalves, P D, Houben, K, Jacobus, J, Jones, A, Kaag, A M, Lindenmeyer, J, McGrath, E, Nardo, T, Oliveira, J, Pennington, C R, Perrykkad, K, Piercy, H, Rupp, C I, Schulte, M H J, Squeglia, L M, Staiger, P, Stein, D J, Stein, J, Stein, M, Stoops, W W, Sweeney, M, Witkiewitz, K, Woods, S P, Yi, R, Zhao, M & Ekhtiari, H 2022, ' Cognitive training and remediation interventions for substance use disorders : a Delphi consensus study ', Addiction . https://doi.org/10.1111/add.16109
Verdejo-Garcia, A, Rezapour, T, Giddens, E, Khojasteh Zonoozi, A, Rafei, P, Berry, J, Caracuel, A, Copersino, M L, Field, M, Garland, E L, Lorenzetti, V, Malloy-Diniz, L, Manning, V, Marceau, E M, Pennington, D L, Strickland, J C, Wiers, R, Fairhead, R, Anderson, A, Bell, M, Boendermaker, W J, Brooks, S, Bruno, R, Campanella, S, Cousijn, J, Cox, W M, Dean, A C, Ersche, K D, Franken, I, Froeliger, B, Gamito, P, Gladwin, T E, Goncalves, P D, Houben, K, Jacobus, J, Jones, A, Kaag, A M, Lindenmeyer, J, McGrath, E, Nardo, T, Oliveira, J, Pennington, C R, Perrykkad, K, Piercy, H, Rupp, C I, Schulte, M H J, Squeglia, L M, Staiger, P, Stein, D J, Stein, J, Stein, M, Stoops, W W, Sweeney, M, Witkiewitz, K, Woods, S P, Yi, R, Zhao, M & Ekhtiari, H 2023, ' Cognitive training and remediation interventions for substance use disorders : a Delphi consensus study ', Addiction, vol. 118, no. 5, pp. 935-951 . https://doi.org/10.1111/add.16109
Addiction, 118(5), 935-951. Wiley-Blackwell
Verdejo-Garcia, Antonio; Rezapour, Tara; Giddens, Emily; Khojasteh Zonoozi, Arash; Rafei, Parnian; Berry, Jamie; Caracuel, Alfonso; Copersino, Marc L; Field, Matt; Garland, Eric L; Lorenzetti, Valentina; Malloy-Diniz, Leandro; Manning, Victoria; Marceau, Ely M; Pennington, David L; Strickland, Justin C; Wiers, Reinout; Fairhead, Rahia; Anderson, Alexandra; Bell, Morris; ... (2023). Cognitive training and remediation interventions for substance use disorders: A Delphi consensus study. Addiction, 118(5), pp. 935-951. Wiley-Blackwell 10.1111/add.16109
Addiction, 118(5), 935-951. Wiley-Blackwell Publishing Ltd
Addiction

Aims: Substance use disorders (SUD) are associated with cognitive deficits that are not always addressed in current treatments, and this hampers recovery. Cognitive training and remediation interventions are well suited to fill the gap for managing c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84bff031d8a015af5897bfe382d42e20
https://doi.org/10.1111/add.16109