Theory-driven computational models of drug addiction in humans: Fruitful or futile?

Autor: Tsen Vei Lim, Karen D Ersche

Publikováno v: Addiction Neuroscience, Vol 5, Iss , Pp 100066- (2023)

Maladaptive behavior in drug addiction is widely regarded as a result of neurocognitive dysfunctions. Recently, there has been a growing trend to adopt computational methods to study these dysfunctions in drug-addicted patients, not least because it

Externí odkaz: https://doaj.org/article/b88717cfdf1d4b9faa29bd97e310ad35

Detecting Small Vessel Pathology in Cocaine Use Disorder

Autor: Marco Öchsner, Elijah Mak, Karen D. Ersche

Publikováno v: Frontiers in Neuroscience, Vol 15 (2022)

BackgroundCocaine use is associated with an increased risk of cerebrovascular accidents. Small vessel pathology has been linked to the risk of stroke in cocaine users, but can be challenging to detect on conventional magnetic resonance (MR) scans. Fl

Externí odkaz: https://doaj.org/article/2c50e387c2434b22bef6a97058d64f0f

'Hot' and 'Cold' Cognition in Users of Club Drugs/Novel Psychoactive Substances

Autor: George Savulich, Owen Bowden-Jones, Robert Stephenson, Annette B. Brühl, Karen D. Ersche, Trevor W. Robbins, Barbara J. Sahakian

Publikováno v: Frontiers in Psychiatry, Vol 12 (2021)

Novel psychoactive substances (NPS) are popular “club/party” drugs that first attracted attention in the UK in 2009 and remained legal until the 2016 Psychoactive Substances Act criminalized their distribution. Unlike “traditional” illicit dr

Externí odkaz: https://doaj.org/article/823705e8670e45d5b1a41d926e0f579b

Cognitive training and remediation interventions for substance use disorders: a Delphi consensus study

Autor: Antonio Verdejo‐Garcia, Tara Rezapour, Emily Giddens, Arash Khojasteh Zonoozi, Parnian Rafei, Jamie Berry, Alfonso Caracuel, Marc L. Copersino, Matt Field, Eric L. Garland, Valentina Lorenzetti, Leandro Malloy‐Diniz, Victoria Manning, Ely M. Marceau, David L. Pennington, Justin C. Strickland, Reinout Wiers, Rahia Fairhead, Alexandra Anderson, Morris Bell, Wouter J. Boendermaker, Samantha Brooks, Raimondo Bruno, Salvatore Campanella, Janna Cousijn, W. Miles Cox, Andrew C. Dean, Karen D. Ersche, Ingmar Franken, Brett Froeliger, Pedro Gamito, Thomas E. Gladwin, Priscila D. Goncalves, Katrijn Houben, Joanna Jacobus, Andrew Jones, Anne M. Kaag, Johannes Lindenmeyer, Elly McGrath, Talia Nardo, Jorge Oliveira, Charlotte R. Pennington, Kelsey Perrykkad, Hugh Piercy, Claudia I. Rupp, Mieke H. J. Schulte, Lindsay M. Squeglia, Petra Staiger, Dan J. Stein, Jeff Stein, Maria Stein, William W. Stoops, Mary Sweeney, Katie Witkiewitz, Steven P. Woods, Richard Yi, Min Zhao, Hamed Ekhtiari

Publikováno v: Addiction, 118, 935-951. Wiley
Verdejo-Garcia, A, Rezapour, T, Giddens, E, Khojasteh Zonoozi, A, Rafei, P, Berry, J, Caracuel, A, Copersino, M L, Field, M, Garland, E L, Lorenzetti, V, Malloy-Diniz, L, Manning, V, Marceau, E M, Pennington, D L, Strickland, J C, Wiers, R, Fairhead, R, Anderson, A, Bell, M, Boendermaker, W J, Brooks, S, Bruno, R, Campanella, S, Cousijn, J, Cox, W M, Dean, A C, Ersche, K D, Franken, I, Froeliger, B, Gamito, P, Gladwin, T E, Goncalves, P D, Houben, K, Jacobus, J, Jones, A, Kaag, A M, Lindenmeyer, J, McGrath, E, Nardo, T, Oliveira, J, Pennington, C R, Perrykkad, K, Piercy, H, Rupp, C I, Schulte, M H J, Squeglia, L M, Staiger, P, Stein, D J, Stein, J, Stein, M, Stoops, W W, Sweeney, M, Witkiewitz, K, Woods, S P, Yi, R, Zhao, M & Ekhtiari, H 2022, ' Cognitive training and remediation interventions for substance use disorders : a Delphi consensus study ', Addiction . https://doi.org/10.1111/add.16109
Verdejo-Garcia, A, Rezapour, T, Giddens, E, Khojasteh Zonoozi, A, Rafei, P, Berry, J, Caracuel, A, Copersino, M L, Field, M, Garland, E L, Lorenzetti, V, Malloy-Diniz, L, Manning, V, Marceau, E M, Pennington, D L, Strickland, J C, Wiers, R, Fairhead, R, Anderson, A, Bell, M, Boendermaker, W J, Brooks, S, Bruno, R, Campanella, S, Cousijn, J, Cox, W M, Dean, A C, Ersche, K D, Franken, I, Froeliger, B, Gamito, P, Gladwin, T E, Goncalves, P D, Houben, K, Jacobus, J, Jones, A, Kaag, A M, Lindenmeyer, J, McGrath, E, Nardo, T, Oliveira, J, Pennington, C R, Perrykkad, K, Piercy, H, Rupp, C I, Schulte, M H J, Squeglia, L M, Staiger, P, Stein, D J, Stein, J, Stein, M, Stoops, W W, Sweeney, M, Witkiewitz, K, Woods, S P, Yi, R, Zhao, M & Ekhtiari, H 2023, ' Cognitive training and remediation interventions for substance use disorders : a Delphi consensus study ', Addiction, vol. 118, no. 5, pp. 935-951 . https://doi.org/10.1111/add.16109
Addiction, 118(5), 935-951. Wiley-Blackwell
Verdejo-Garcia, Antonio; Rezapour, Tara; Giddens, Emily; Khojasteh Zonoozi, Arash; Rafei, Parnian; Berry, Jamie; Caracuel, Alfonso; Copersino, Marc L; Field, Matt; Garland, Eric L; Lorenzetti, Valentina; Malloy-Diniz, Leandro; Manning, Victoria; Marceau, Ely M; Pennington, David L; Strickland, Justin C; Wiers, Reinout; Fairhead, Rahia; Anderson, Alexandra; Bell, Morris; ... (2023). Cognitive training and remediation interventions for substance use disorders: A Delphi consensus study. Addiction, 118(5), pp. 935-951. Wiley-Blackwell 10.1111/add.16109
Addiction, 118(5), 935-951. Wiley-Blackwell Publishing Ltd
Addiction

Aims: Substance use disorders (SUD) are associated with cognitive deficits that are not always addressed in current treatments, and this hampers recovery. Cognitive training and remediation interventions are well suited to fill the gap for managing c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84bff031d8a015af5897bfe382d42e20
https://doi.org/10.1111/add.16109

Prefrontal Cortex Activation and Stopping Performance Underlie the Beneficial Effects of Atomoxetine on Response Inhibition in Healthy Volunteers and Those With Cocaine Use Disorder

Autor: Barbara J. Sahakian, Sharon Morein-Zamir, Hisham Ziauddeen, Peter Zhukovsky, Emilio Fernandez-Egea, Trevor W. Robbins, Ralf Regenthal, Jeffrey W. Dalley, Chun Meng, Karen D. Ersche, Edward T. Bullmore

Publikováno v: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 7:1116-1126

Background Impaired response inhibition in individuals with cocaine use disorder (CUD) is hypothesized to depend on deficient noradrenergic signaling in corticostriatal networks. Remediation of noradrenergic neurotransmission with selective norepinep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49af336145c9824d8b108f22346ae47a
https://doi.org/10.1016/j.bpsc.2021.08.010