Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Karen Coopman"'
Autor:
Lisa Barrett, Karen Coopman
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 52, Iss 1, Pp 345-354 (2024)
Cell encapsulation into spherical microparticles is a promising bioengineering tool in many fields, including 3D cancer modelling and pre-clinical drug discovery. Cancer microencapsulation models can more accurately reflect the complex solid tumour m
Externí odkaz:
https://doaj.org/article/8d5994a6fb34490c94bb93404dd98a46
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract Background The effects of cryopreservation on human bone marrow-derived mesenchymal stem cells (hBM-MSCs) are still ill-defined. In this study, a quantitative approach was adopted to measure several post-thaw cell attributes in order to prov
Externí odkaz:
https://doaj.org/article/1b1c25dfc9a84d879c2549feba7bd55c
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-29 (2019)
Abstract Mesenchymal stem cells (MSCs) represent an invaluable asset for the field of cell therapy. Human Bone marrow-derived MSCs (hBM-MSCs) are one of the most commonly used cell types in clinical trials. They are currently being studied and tested
Externí odkaz:
https://doaj.org/article/e599f38f834e482289a1216ed961b4ca
Autor:
Rebecca Grant, Karen Coopman, Sandro Silva-Gomes, Jonathan J. Campbell, Bo Kara, Julian Braybrook, Jon Petzing
Publikováno v:
Methods and Protocols, Vol 4, Iss 2, p 24 (2021)
Measured variability of product within Cell and Gene Therapy (CGT) manufacturing arises from numerous sources across pre-analytical to post-analytical phases of testing. Operators are a function of the manufacturing process and are an important sourc
Externí odkaz:
https://doaj.org/article/ea948a785baf45848f1387ff700a1777
Publikováno v:
Polymers, Vol 9, Iss 12, p 687 (2017)
As electroactive polymers have recently presented potential in applications in the tissue engineering and biomedical field, this study is aiming at the fabrication of composite nanofibrous membranes containing conducting polyaniline and at the evalua
Externí odkaz:
https://doaj.org/article/00f7abe682bd468f8f20fb7614f511ee
Publikováno v:
Biopreservation and Biobanking.
Autor:
Andrzej W. Pacek, Halina Murasiewicz, Alvin W. Nienow, Christopher J. Hewitt, Mariana P. Hanga, Karen Coopman
Publikováno v:
Journal of Chemical Technology and Biotechnology
BACKGROUND Traditional large‐scale culture systems for human mesenchymal stem/stromal cells (hMSCs) use solid microcarriers as attachment substrates. Although the use of such substrates is advantageous because of the high surface‐to‐volume rati
Autor:
Nick Medcalf, Karen Coopman, Julian Braybrook, Jon N. Petzing, Bo Kara, Jonathan Campbell, Rebecca Grant, Sandro Silva-Gomes
Publikováno v:
PDA Journal of Pharmaceutical Science and Technology. 75:33-47
Flow cytometry is a complex measurement characterization technique, utilized within the manufacture, measurement, and release of cell and gene therapy products for rapid, high-content, and multiplexed discriminatory cell analysis. A number of factors
Publikováno v:
Current Nanomaterials. 4:6-20
Background: Within the healthcare industry, including the care of chronic wounds, the challenge of antimicrobial resistance continues to grow. As such, there is a need to develop new treatments that can reduce the bioburden in wounds. Objective: The
Autor:
Qasim A. Rafiq, Bo Kara, Karen Coopman, Alvin W. Nienow, Christopher J. Hewitt, Thomas R.J. Heathman
Publikováno v:
Biochemical Engineering Journal. 141:200-209
Human Mesenchymal Stem Cells (hMSCs) are advancing through clinical development with the first allogeneic adult hMSC therapy receiving approval in Europe. To enable successful large-scale manufacture of hMSC therapies, increased product consistency a