Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Karen Clise-Dwyer"'
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101764- (2022)
Summary: Drug testing assays in hematopoietic stem and progenitor cells (HSPCs) are fundamental in biological studies of myelodysplastic syndromes (MDS) but have historically entailed a technical challenge. This protocol allows the efficient isolatio
Externí odkaz:
https://doaj.org/article/41d5d3c09aa140d1b729b74dfd7f47b3
Autor:
Alexandre Reuben, Christine N. Spencer, Peter A. Prieto, Vancheswaran Gopalakrishnan, Sangeetha M. Reddy, John P. Miller, Xizeng Mao, Mariana Petaccia De Macedo, Jiong Chen, Xingzhi Song, Hong Jiang, Pei-Ling Chen, Hannah C. Beird, Haven R. Garber, Whijae Roh, Khalida Wani, Eveline Chen, Cara Haymaker, Marie-Andrée Forget, Latasha D. Little, Curtis Gumbs, Rebecca L. Thornton, Courtney W. Hudgens, Wei-Shen Chen, Jacob Austin-Breneman, Robert Szczepaniak Sloane, Luigi Nezi, Alexandria P. Cogdill, Chantale Bernatchez, Jason Roszik, Patrick Hwu, Scott E. Woodman, Lynda Chin, Hussein Tawbi, Michael A. Davies, Jeffrey E. Gershenwald, Rodabe N. Amaria, Isabella C. Glitza, Adi Diab, Sapna P. Patel, Jianhua Hu, Jeffrey E. Lee, Elizabeth A. Grimm, Michael T. Tetzlaff, Alexander J. Lazar, Ignacio I. Wistuba, Karen Clise-Dwyer, Brett W. Carter, Jianhua Zhang, P. Andrew Futreal, Padmanee Sharma, James P. Allison, Zachary A. Cooper, Jennifer A. Wargo
Publikováno v:
npj Genomic Medicine, Vol 2, Iss 1, Pp 1-11 (2017)
Melanoma: Tumor differences within a patient may explain heterogeneous responses Patients with metastatic melanoma display molecular and immune differences across tumor sites associated with differential drug responses. A team led by Jennifer Wargo f
Externí odkaz:
https://doaj.org/article/95f4f8da81aa4220b7ea3fea4b7af4b6
Autor:
Amanda C. Herrmann, Jin S. Im, Sumedha Pareek, Wilfredo Ruiz-Vasquez, Sijie Lu, Anna Sergeeva, Jennifer Mehrens, Hong He, Gheath Alatrash, Pariya Sukhumalchandra, Lisa St. John, Karen Clise-Dwyer, Dongxing Zha, Jeffrey J. Molldrem
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Despite substantial advances in the treatment of acute myeloid leukemia (AML), only 30% of patients survive more than 5 years. Therefore, new therapeutics are much needed. Here, we present a novel therapeutic strategy targeting PR1, an HLA-A2 restric
Externí odkaz:
https://doaj.org/article/1f58451747bb46a189b44e4e06877097
Cathepsin G Is Expressed by Acute Lymphoblastic Leukemia and Is a Potential Immunotherapeutic Target
Autor:
Maliha Khan, Selena Carmona, Pariya Sukhumalchandra, Jason Roszik, Anne Philips, Alexander A. Perakis, Celine Kerros, Mao Zhang, Na Qiao, Lisa S. St. John, Madhushree Zope, Jonathan Goldberg, Mariam Qazilbash, Haroon Jakher, Karen Clise-Dwyer, Yihua Qiu, Elizabeth A. Mittendorf, Jeffrey J. Molldrem, Steven M. Kornblau, Gheath Alatrash
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
Cathepsin G (CG) is a myeloid azurophil granule protease that is highly expressed by acute myeloid leukemia (AML) blasts and leukemia stem cells. We previously identified CG1 (FLLPTGAEA), a human leukocyte antigen-A2-restricted nonameric peptide deri
Externí odkaz:
https://doaj.org/article/b6df8da3c28b4eaa907aea2ac7cee27d
Autor:
Hong Jiang, Karen Clise-Dwyer, Kathryn E Ruisaard, Xuejun Fan, Weihua Tian, Joy Gumin, Martine L Lamfers, Anne Kleijn, Frederick F Lang, Wai-Kwan Alfred Yung, Luis M Vence, Candelaria Gomez-Manzano, Juan Fueyo
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97407 (2014)
Emerging evidence suggests anti-cancer immunity is involved in the therapeutic effect induced by oncolytic viruses. Here we investigate the effect of Delta-24-RGD oncolytic adenovirus on innate and adaptive anti-glioma immunity.Mouse GL261-glioma mod
Externí odkaz:
https://doaj.org/article/fb4673f3b2904821a7d5b9efeabd6a3b
Autor:
Shreya Kanodia, Eric Wieder, Sijie Lu, Moshe Talpaz, Gheath Alatrash, Karen Clise-Dwyer, Jeffrey J Molldrem
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11770 (2010)
Interferon-alpha (IFN) induces complete cytogenetic remission (CCR) in 20-25% CML patients and in a small minority of patients; CCR persists after IFN is stopped. IFN induces CCR in part by increasing cytotoxic T lymphocytes (CTL) specific for PR1, t
Externí odkaz:
https://doaj.org/article/2db8671c3fcd4d91a8ed7331c5f329d2
Autor:
Mekenzie M. Peshoff, Pravesh Gupta, Rakesh Trivedi, Shivangi Oberai, Prashanth Chakrapani, Minghao Dang, Nancy Milam, Mark E. Maynard, Brian D. Vaillant, Jason T. Huse, Linghua Wang, Karen Clise-Dwyer, Krishna P. Bhat
Glioblastomas (GBMs) are tumors of the central nervous system that remain recalcitrant to both standard of care chemo-radiation and immunotherapies. Emerging approaches to treat GBMs include depletion or re-education of innate immune cells including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7ac01fdf06ba398e1cd085b8b9bc7f5
https://doi.org/10.1101/2023.04.05.535792
https://doi.org/10.1101/2023.04.05.535792
Autor:
Maria Teresa S. Bertilaccio, Michael J. Keating, Varsha Gandhi, Federico Caligaris-Cappio, William Plunkett, William Wierda, Christian Klein, Miguel Aracil, Lydia Scarfò, Federica Barbaglio, Karen Clise-Dwyer, Giovanni Galletti, Cristina Ivan, Ronghua Zhang, Priyanka Banerjee
Supplementary Tables S1-S12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522de18b3bcdc312492ff1514ad75066
https://doi.org/10.1158/2326-6066.22542124.v1
https://doi.org/10.1158/2326-6066.22542124.v1
Autor:
Simona Colla, Gerd A. Blobel, Guillermo Garcia-Manero, Karen Clise-Dwyer, Gheath Al-Atrash, Valeria Santini, Stephanie Halene, Jennifer S. Carew, Rafael Bejar, Tuyet M. Tan, Matteo Pellegrini, Carlos Bueso-Ramos, Yuanbin Song, Irene Gañán-Gómez, Valeria Visconte, Jaroslaw P. Maciejewski, Margherita Cassari, Pamela Lockyer, Francesc Sole, Pamela Acha, Feng Wang, Scott A. Peslak, Hui Yang, Guillermo Montalban-Bravo, Natthakan Thongon, Rashmi Kanagal-Shamanna, Feiyang Ma, Vera Adema
Supplementary Data from Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in SF3B1-Mutant Myelodysplastic Syndromes With Ringed Sideroblasts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5865c40b6e6adc3d75741f8245104f3f
https://doi.org/10.1158/2643-3230.22545554
https://doi.org/10.1158/2643-3230.22545554
Autor:
Maria Teresa S. Bertilaccio, Michael J. Keating, Varsha Gandhi, Federico Caligaris-Cappio, William Plunkett, William Wierda, Christian Klein, Miguel Aracil, Lydia Scarfò, Federica Barbaglio, Karen Clise-Dwyer, Giovanni Galletti, Cristina Ivan, Ronghua Zhang, Priyanka Banerjee
Supplementary Figures S1-S17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b01748f9bcc2ad4b6862b874b4c0877
https://doi.org/10.1158/2326-6066.22542127
https://doi.org/10.1158/2326-6066.22542127