Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Karen C Young"'
Autor:
Marissa J. DeFreitas, Elaine L. Shelton, Augusto F. Schmidt, Sydne Ballengee, Runxia Tian, PingPing Chen, Mayank Sharma, Amanda Levine, Emily Davidovic Katz, Claudia Rojas, Carolyn L. Abitbol, Juanita Hunter, Shathiyah Kulandavelu, Shu Wu, Karen C. Young, Merline Benny
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Premature infants are often exposed to hyperoxia. However, there is limited data regarding the mechanistic underpinnings linking neonatal hyperoxia exposure and its contribution to cardio-renal dysfunction in adults born preterm. Our objecti
Externí odkaz:
https://doaj.org/article/e9a60e9e92eb4d72a57c04ca58addd22
Autor:
Ibrahim Sammour, Santhosh Somashekar, Jian Huang, Sunil Batlahally, Matthew Breton, Krystalenia Valasaki, Aisha Khan, Shu Wu, Karen C Young
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164269 (2016)
Mesenchymal stem cells (MSC) improve alveolar and vascular structures in experimental models of bronchopulmonary dysplasia (BPD). Female MSC secrete more anti-inflammatory and pro-angiogenic factors as compared to male MSC. Whether the therapeutic ef
Externí odkaz:
https://doaj.org/article/7ea9040cebd842f38d82cbb82f13d7e4
Autor:
Josef Newman, Xiaoying Tong, April Tan, Toni Yeasky, Vanessa Nunes De Paiva, Pietro Presicce, Paranthaman S. Kannan, Kevin Williams, Andreas Damianos, Marione Tamase Newsam, Merline K. Benny, Shu Wu, Karen C. Young, Lisa A. Miller, Suhas G. Kallapur, Claire A. Chougnet, Alan H. Jobe, Roberta Brambilla, Augusto F. Schmidt
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract Background Preterm birth is often associated with chorioamnionitis and leads to increased risk of neurodevelopmental disorders, such as autism. Preterm birth can lead to cerebellar underdevelopment, but the mechanisms of disrupted cerebellar
Externí odkaz:
https://doaj.org/article/4330d26737704358ad8660367418ee35
Autor:
Merline Benny, Mayank Sharma, Shathiyah Kulandavelu, PingPing Chen, Runxia Tian, Sydne Ballengee, Jiang Huang, Amanda F. Levine, Matteo Claure, Augusto F. Schmidt, Roberto I. Vazquez-Padron, Claudia O. Rodrigues, Shu Wu, Omaida C. Velazquez, Karen C. Young
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Neonatal hyperoxia induces long-term systemic vascular stiffness and cardiovascular remodeling, but the mechanisms are unclear. Chemokine receptor 7 (CXCR7) represents a key regulator of vascular homeostasis and repair by modulating TGF-β1
Externí odkaz:
https://doaj.org/article/1734e60b83044990a6ea1ecd3cf191fc
Autor:
April W. Tan, Xiaoying Tong, Silvia Alvarez-Cubela, Pingping Chen, Aline Guimarães Santana, Alejo A. Morales, Runxia Tian, Rae Infante, Vanessa Nunes de Paiva, Shathiyah Kulandavelu, Merline Benny, Juan Dominguez-Bendala, Shu Wu, Karen C. Young, Claudia O. Rodrigues, Augusto F. Schmidt
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Background: Intra-amniotic inflammation (IAI) is associated with increased risk of preterm birth and bronchopulmonary dysplasia (BPD), but the mechanisms by which IAI leads to preterm birth and BPD are poorly understood, and there are no effective th
Externí odkaz:
https://doaj.org/article/c3673c1112084506864b0db5ed712490
Autor:
Shu Wu, Merline Benny, Joanne Duara, Kevin Williams, April Tan, Augusto Schmidt, Karen C. Young
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Extracellular vesicles (EVs) are a heterogeneous group of nano-sized membranous structures increasingly recognized as mediators of intercellular and inter-organ communication. EVs contain a cargo of proteins, lipids and nucleic acids, and their cargo
Externí odkaz:
https://doaj.org/article/1778b43eee454983988a9172e0e48767
Autor:
Daniela Aguilar-Caballero, Jose M. C. Capcha, Veronica Caballero, Karen C. Young, Shahnaz Duara, Michael Borchetta, Ivan Gonzalez, Ali G. Saad, Keith A. Webster, Lina A. Shehadeh, Emmalee S. Bandstra, Augusto F. Schmidt
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Vertical transmission of SARS-CoV-2 from mother to fetus is widely accepted. Whereas most infected neonates present with mild symptoms or are asymptomatic, respiratory distress syndrome (RDS) and abnormal lung images are significantly more frequent i
Externí odkaz:
https://doaj.org/article/1d6865de636c4485bd22d2241280863c
Autor:
Laura Chavez, Julia Meguro, Shaoyi Chen, Vanessa Nunes de Paiva, Ronald Zambrano, Julia M. Eterno, Rahul Kumar, Matthew R. Duncan, Merline Benny, Karen C. Young, W. Dalton Dietrich, Roberta Brambilla, Shu Wu, Augusto F. Schmidt
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-11 (2021)
Abstract Background Mechanical ventilation of preterm newborns causes lung injury and is associated with poor neurodevelopmental outcomes. However, the mechanistic links between ventilation-induced lung injury (VILI) and brain injury is not well defi
Externí odkaz:
https://doaj.org/article/1c2d4c8e19ab440aa20d10a917dd6be6
Autor:
Merline Benny, Diana R. Hernandez, Mayank Sharma, Keyvan Yousefi, Shathiyah Kulandavelu, Sunil Batlahally, Ronald Zambrano, Pingping Chen, Eliana C. Martinez, Augusto F. Schmidt, Lina A. Shehadeh, Roberto I. Vazquez‐Padron, Shu Wu, Omaida C. Velazquez, Karen C. Young
Publikováno v:
Physiological Reports, Vol 8, Iss 1, Pp n/a-n/a (2020)
Abstract Supplemental oxygen (O2) therapy in preterm infants impairs lung development, but the impact of O2 on long‐term systemic vascular structure and function has not been well‐explored. The present study tested the hypothesis that neonatal O2
Externí odkaz:
https://doaj.org/article/bd9fec0483194b249531c4ec54aa9250
Autor:
Karen C. Young, Daniel A. Meza, Basil Khuder, Sharon R. Rosenberg, Gabrielle Y. Liu, Jacqueline M. Kruser, Paul A. Reyfman, Ravi Kalhan
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 206:1044-1047
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91cf81609170765aa2339e6aa65e2066
https://doi.org/10.1164/rccm.202112-2807le
https://doi.org/10.1164/rccm.202112-2807le