Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Karen Brebner"'
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Lactate, the redox-balanced end product of glycolysis, travels within and between cells to fulfill an array of physiologic functions. While evidence for the centrality of this lactate shuttling in mammalian metabolism continues to mount, its applicat
Externí odkaz:
https://doaj.org/article/b6ae726faec74f739593794e547d1659
Autor:
Aakash Patel, Hala Guedouari, Elzbieta Janda, Karine Reybier, Istvan Gacsalyi, Vishalgiri Goswami, Jean A. Boutin, Adeline Giganti, Mathias Antoine, Monivan Chhour, Marie-Claude Viaud-Massuard, Hervé Da Costa, Marc Bertrand, Pierre Ducrot, Jérôme Paysant, Patrick P. Michel, Gilles Ferry, Thierry Le Diguarher, Daniel A. Kane, Françoise Nepveu, Frédéric Bouillaud, Karen Brebner, Gérald Guillaumet, Etienne C. Hirsch, Philippe Dupuis, Johann Stojko
Publikováno v:
Molecular Pharmacology
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2019, 95 (3), pp.269-285. ⟨10.1124/mol.118.114231⟩
Molecular Pharmacology, 2019, 95 (3), pp.269-285. ⟨10.1124/mol.118.114231⟩
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 2019, 95 (3), pp.269-285. ⟨10.1124/mol.118.114231⟩
Molecular Pharmacology, 2019, 95 (3), pp.269-285. ⟨10.1124/mol.118.114231⟩
International audience; Quinone reductase 2 (QR2, E.C. 1.10.5.1) is an enzyme with a feature that has attracted attention for several decades: in standard conditions, instead of recognizing NAD(P)H as an electron donor, it recognizes putative metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c332ae7dd4579c5014783569d4574301
https://www.hal.inserm.fr/inserm-02334766
https://www.hal.inserm.fr/inserm-02334766
Autor:
Laura R. Davidson, Daniel A. Kane, Mackenzie Cw. Bell, Karen Brebner, Helen Elizabeth Wallace
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33e8d90d556dccdcdf32b515efa0abe6
https://doi.org/10.1096/fasebj.2018.32.1_supplement.618.11
https://doi.org/10.1096/fasebj.2018.32.1_supplement.618.11
Autor:
Laura R. Davidson, Mackenzie Cw. Bell, Helen Elizabeth Wallace, Karen Brebner, Daniel A. Kane
Publikováno v:
The FASEB Journal. 32
Exercise has been shown to stimulate histamine release, which mediates vasodilation in exercising tissue and is sustained post-exercise. Blockade of H1 and H2 receptors with antihistamine drugs att...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::699363671c3f04d9dac8898600ed4ece
https://doi.org/10.1096/fasebj.2018.32.1_supplement.587.11
https://doi.org/10.1096/fasebj.2018.32.1_supplement.587.11
Publikováno v:
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 43(5)
The nature and existence of mitochondrial lactate oxidation is debated in the literature. Obscuring the issue are disparate findings in isolated mitochondria, as well as relatively low rates of lactate oxidation observed in permeabilized muscle fibre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::160c2456ec1e63ec2a14f3fab3eebfa7
https://pubmed.ncbi.nlm.nih.gov/29206478
https://pubmed.ncbi.nlm.nih.gov/29206478
Publikováno v:
Psychopharmacology. 232(24)
L-type Ca2+ channels (LTCC) and GABAB receptors are both possible targets in the development of new pharmacological compounds for cocaine addiction. Drugs that target either receptor attenuate a wide range of cocaine-seeking behaviors in the rat. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6aadd480e09ab8f748bff9a0cd7fbf
https://pubmed.ncbi.nlm.nih.gov/26345344
https://pubmed.ncbi.nlm.nih.gov/26345344
Autor:
David C.S. Roberts, Karen Brebner
Publikováno v:
Annals of the New York Academy of Sciences. 909:145-158
Recent experiments suggest that GABA compounds produce a clinically relevant modulation of cocaine reinforcement. This review summarizes the results of a number of studies that examined the effect of the GABAB agonist baclofen on cocaine self-adminis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa4cf36708c554d72bd78f977a9c7f6
https://doi.org/10.1111/j.1749-6632.2000.tb06680.x
https://doi.org/10.1111/j.1749-6632.2000.tb06680.x
Publikováno v:
Psychopharmacology. 177:409-417
Recent reports have demonstrated that gamma-aminobutyric acid (GABA)-ergic compounds attenuate the reinforcing effects of cocaine in rats. Baclofen, a GABA(B) receptor agonist, appears to be particularly effective in this respect, suggesting that GAB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37841e7dc791998af2b46d2a2081ab80
https://doi.org/10.1007/s00213-004-1968-6
https://doi.org/10.1007/s00213-004-1968-6
Publikováno v:
Drug and Alcohol Dependence. 67:291-299
Frequency of drug access greatly affects the pattern and stability of cocaine self-administration. Previous research has shown that restricted drug availability produces remarkably consistent levels of daily cocaine intake, whereas increased or unlim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fe993987d91c6f8f781486edeccf97
https://doi.org/10.1016/s0376-8716(02)00083-2
https://doi.org/10.1016/s0376-8716(02)00083-2