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pro vyhledávání: '"Karen Boisvert"'
Melanoma is a particularly aggressive tumor type that exhibits a high level of resistance to apoptosis. The serine/threonine kinase B-RAF is mutated in 50% to 70% of melanomas and protects melanoma cells from anoikis, a form of apoptosis induced by l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e0202614d585f024a2aa63a872ddf5
https://doi.org/10.1158/1541-7786.c.6542034
https://doi.org/10.1158/1541-7786.c.6542034
Autor:
R. Gilberto Gonzalez, Lakshmanan Annamalai, Karen Boisvert, Susan V. Westmoreland, Gregory M. Miller, Margaret R. Lentz, Basel T. Assaf, Thanhthao Huynh, Eva M. Ratai, Eric J. Vallender, Bertha K. Madras
Publikováno v:
Journal of NeuroVirology. 17:455-468
Understanding the mechanisms of neuronal regeneration and repair in the adult central nervous system is a vital area of research. Using a rhesus lentiviral encephalitis model, we sought to determine whether recovery of neuronal metabolism after injur
Autor:
M. A. Fahey, Karen Boisvert, Susan V. Westmoreland, Makoto Ohashi, Fred Wang, Shawn P. O'Neil, Amanda K. Marr-Belvin, A. K. Carville, Sherry Klumpp
Publikováno v:
Veterinary Pathology. 45:914-921
Epstein-Barr virus (EBV) is a worldwide endemic gamma herpesvirus of the genus Lymphocryptovirus (LCV) that infects more than 90% of the world's population. EBV has been associated with a variety of malignancies, but it has a demonstrated role in lym
Autor:
Karen Boisvert, Greice Krautz-Peterson, Saul Tzipori, Susan Chapman-Bonofiglio, Hanping Feng, Abhineet S. Sheoran, Ira M. Herman
Publikováno v:
Infection and Immunity. 76:1931-1939
Infection of children with Shiga toxin (Stx)-producing Escherichia coli (STEC) is the leading cause of hemolytic-uremic syndrome (HUS). Stx2, one of two toxins liberated by the bacteria, is directly linked with HUS. We have previously shown that Stx2
Autor:
D. G. Walsh, Amitinder Kaur, Amanda J. Martinot, Mareike Meythaler, Karen Boisvert, Susan V. Westmoreland, Heather Knight, Daniel C. Anderson, Shawn P. O'Neil, Lu-Ann Pozzi
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57785 (2013)
PLoS ONE
PLoS ONE
Lymphoid tissue immunopathology is a characteristic feature of chronic HIV/SIV infection in AIDS-susceptible species, but is absent in SIV-infected natural hosts. To investigate factors contributing to this difference, we compared germinal center dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341ea8f41b784cf9a4f2defdde120a0c
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/3255
https://opus4.kobv.de/opus4-fau/frontdoor/index/index/docId/3255
Publikováno v:
Molecular cancer research : MCR. 7(4)
Melanoma is a particularly aggressive tumor type that exhibits a high level of resistance to apoptosis. The serine/threonine kinase B-RAF is mutated in 50% to 70% of melanomas and protects melanoma cells from anoikis, a form of apoptosis induced by l
Autor:
Karen Boisvert-Adamo, Andrew E. Aplin
Publikováno v:
Oncogene. 27(23)
Normal cells undergo anoikis when they lose adhesion to or encounter an inappropriate extracellular matrix. By contrast, oncogenic signaling in tumor cells enables resistance to anoikis, a trait that contributes to tumor progression. The B-RAF serine
D-type cyclins regulate G1 cell cycle progression by enhancing the activities of cyclin-dependent kinases (CDKs), and their expression is frequently altered in malignant cells. We and others have previously shown that cyclin D1 is up-regulated in mel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d1f4dfca0141e6264965bcf5ed4bbd
https://europepmc.org/articles/PMC4266577/
https://europepmc.org/articles/PMC4266577/
Autor:
Andrew E. Aplin, Karen Boisvert-Adamo
Publikováno v:
Oncogene. 25(35)
A hallmark feature of cancer is resistance to anoikis, apoptosis induced when cells either lose contact with or encounter an inappropriate extracellular matrix. Melanoma is inherently associated with a high degree of resistance to apoptosis. Mutation
Publikováno v:
The Journal of infectious diseases. 189(9)
Mycobacterium avium complex (MAC) infection is the most common disseminated bacterial infection in untreated patients with acquired immunodeficiency syndrome (AIDS). We investigated the potential role of monocyte chemotactic protein-1 (MCP-1) in the