Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Karen B. Young"'
Autor:
Guoxiang Chu, Evangelia G. Kranias, Wen Zhao, Karen B. Young, Konrad Frank, Yoji Sato, Laurence Mesnard-Rouiller, Kobra Haghighi
Publikováno v:
Basic Research in Cardiology. 96:636-644
Calsequestrin is a sarcoplasmic reticulum protein, which plays a predominant role in diastolic Ca2+-storage in the mammalian heart. The present study was designed to define the gene structure, developmental and tissue specific expression of the murin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39138107b0093d29ad2b2ab506692325
https://doi.org/10.1007/s003950170016
https://doi.org/10.1007/s003950170016
Autor:
Karen B. Young, Evangelia G. Kranias, Michael J Gerst, James Gulick, Jeffrey Robbins, Qiujing Song, Guoxiang Chu, Ingrid L. Grupp
Publikováno v:
The FASEB Journal. 18:974-976
The relative amount of sarcoplasmic reticulum Ca2+-ATPase (SERCA2a) and its crucial inhibitor phospholamban (PLN) are closely regulated and play a pivotal role in maintaining muscle function. The functional importance of PLN has been intensively inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7371dde9960fa1cba900e5ae6d4576
https://doi.org/10.1096/fj.03-1058fje
https://doi.org/10.1096/fj.03-1058fje
Publikováno v:
Journal of religionspirituality in social work. 29(1)
This descriptive, exploratory study is part of a larger observational study of the quality of cancer care delivered to population-based cohorts of newly-diagnosed patients with lung and colorectal cancer. The current study explores the role of spirit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4108fd8539d30f513ea30e7eca95c084
https://pubmed.ncbi.nlm.nih.gov/20625520
https://pubmed.ncbi.nlm.nih.gov/20625520
Autor:
Karen B. Young, Jeffrey Robbins, Melissa C. Colbert, Guoxiang Chu, Paul D. Lampe, Konrad Frank, Evangelia G. Kranias, Atsushi Sanbe, Steven M. Schwartz, Andrew N. Carr, Atsuko Yatani, Jeffery D. Molkentin, J.William Lester
Publikováno v:
Cardiovascular research. 54(1)
Objective: Impaired myocyte Ca2+ handling is a common characteristic of failing hearts and increases in calcineurin activity, a Ca2+-sensitive phosphatase, have been implicated in heart failure phenotype. Transgenic mice with cardiac-specific express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a70a8f6bc6d14ec096da32c3fcdce1
https://pubmed.ncbi.nlm.nih.gov/12062367
https://pubmed.ncbi.nlm.nih.gov/12062367
Publikováno v:
Developments in Cardiovascular Medicine ISBN: 9781461356615
Animal models have provided invaluable tools in improving our understanding of cardiac physiology and the mechanisms underlying heart disease. Until recently, available models were generated by surgical or pharmacological interventions or were the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5388d447e2cb6795431cd8867a04c5be
https://doi.org/10.1007/978-1-4615-1653-8_2
https://doi.org/10.1007/978-1-4615-1653-8_2
Publikováno v:
The Journal of biological chemistry. 275(49)
Phospholamban (PLB) can be phosphorylated at Ser(16) by cyclic AMP-dependent protein kinase and at Thr(17) by Ca(2+)-calmodulin-dependent protein kinase during beta-agonist stimulation. A previous study indicated that mutation of S16A in PLB resulted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3573256e270c2f46c0136e0435424f3a
https://pubmed.ncbi.nlm.nih.gov/10988285
https://pubmed.ncbi.nlm.nih.gov/10988285
Autor:
Qiujing Song, Jeffrey Robbinst, Ingrid L. Grupp, Evangelia G. Kranias, Karen B. Young, Guoxiang Chu, Michael J Gerst
Publikováno v:
Journal of Molecular and Cellular Cardiology. 33:A135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::577fa55b3a5adfc1bfe337a95dab0d31
https://doi.org/10.1016/s0022-2828(01)90536-x
https://doi.org/10.1016/s0022-2828(01)90536-x