Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Karen B, King"'
Publikováno v:
PLoS ONE, Vol 18, Iss 7, p e0287825 (2023)
Individuals with type 2 diabetes mellitus (T2DM) have a higher fracture risk compared to those without T2DM despite having higher bone mineral density (BMD). Thus, T2DM may alter other aspects of resistance to fracture beyond BMD such as bone geometr
Externí odkaz:
https://doaj.org/article/d52d557d1d5748fa812902d31b2f4ed1
Autor:
Karen B. King, Ashley M. Torres, Grażyna E. Sroga, Jonathan E. Jo, Eric Marty, Rehan Saiyed, Deepak Vashishth, Heather B Hunt, Matthew R. Cohn, Eve Donnelly, Christopher J. Hernandez, Joseph M. Lane, Pablo M Palomino, Stephen J. Warner
Publikováno v:
J Bone Miner Res
People with type 2 diabetes mellitus (T2DM) have normal-to-high BMDs, but, counterintuitively, have greater fracture risks than people without T2DM, even after accounting for potential confounders like BMI and falls. Therefore, T2DM may alter aspects
Publikováno v:
Bone. 110:115-127
Osteocytes can participate in systemic mineral homeostasis through perilacunar maintenance and remodeling, where changes to osteocyte lacunar morphology may affect bone structural integrity, tissue strains, and osteocyte mechanosensitivity. Though ag
Publikováno v:
Journal of Bone and Mineral Research. 33:921-929
Type 2 diabetes mellitus (T2DM) increases fracture risk for a given bone mineral density (BMD), which suggests that T2DM changes bone tissue properties independently of bone mass. In this study, we assessed the effects of hyperglycemia on bone tissue
Autor:
Ryan Clark, Karen B. King, Andrew Cureton, Alicia Ortega, Moshe Levi, Ted A. Bateman, Eric W. Livingston, Chelsea M. Heveran, Virginia L. Ferguson
Publikováno v:
Bone. 86:1-9
Chronic kidney disease (CKD) increases bone fracture risk. While the causes of bone fragility in CKD are not clear, the disrupted mineral homeostasis inherent to CKD may cause material quality changes to bone tissue. In this study, 11-week old male C
Autor:
Karen B. King, Ann K. Rosenthal
Publikováno v:
Osteoarthritis and Cartilage. 23:841-850
SummaryProjected increases in the prevalence of both diabetes mellitus (DM) and osteoarthritis (OA) ensure their common co-existence. In an era of increasing attention to personalized medicine, understanding the influence of common comorbidities such
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 33(5)
Type 2 diabetes mellitus (T2DM) increases fracture risk for a given bone mineral density (BMD), which suggests that T2DM changes bone tissue properties independently of bone mass. In this study, we assessed the effects of hyperglycemia on bone tissue
Publikováno v:
JBJS Reviews. 4
Diabetes has negative effects on the outcomes of total joint arthroplasty, including increased numbers of complications, decreased function, early revision, and higher costs. The prevalence of diabetes is increasing rapidly worldwide; therefore, the
Publikováno v:
Journal of Orthopaedic Research. 27:1408-1413
The aim of this study was to test the hypothesis that a change in serum cartilage oligomeric matrix protein (COMP) concentration is related to joint load during a 30-min walking exercise in patients with medial compartment knee osteoarthritis (OA) an
Publikováno v:
Journal of Orthopaedic Research. 25:1176-1184
We reported previously the formation of microtears in an in vivo loaded Flexor Digitorum Profundus (FDP) rabbit tendon with a repetition rate of 60 repetitions per minute and a peak force of 15% of maximum peak tetanic force for 80 cumulative hours.