Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Karen Axelgaard Lorentzen"'
Autor:
Karen Axelgaard Lorentzen, Raquel Hernanz, Estéfano Pinilla, Jens Randel Nyengaard, Lise Wogensen, Ulf Simonsen
Publikováno v:
Lorentzen, K A, Hernanz, R, Pinilla, E, Nyengaard, J R, Wogensen, L & Simonsen, U 2023, ' Sex-Dependent Impairment of Endothelium-Dependent Relaxation in Aorta of Mice with Overexpression of Hyaluronan in Tunica Media ', International Journal of Molecular Sciences, vol. 24, no. 9 . https://doi.org/10.3390/ijms24098436
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8436
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8436
Diabetic macroangiopathy is characterized by increased extracellular matrix deposition, including excessive hyaluronan accumulation, vessel thickening and stiffness, and endothelial dysfunction in large arteries. We hypothesized that the overexpressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a3393c638058f4dd90d0ac009ea442
https://pure.au.dk/portal/da/publications/sexdependent-impairment-of-endotheliumdependent-relaxation-in-aorta-of-mice-with-overexpression-of-hyaluronan-in-tunica-media(7c2129cc-df94-4736-bcfc-173fee213736).html
https://pure.au.dk/portal/da/publications/sexdependent-impairment-of-endotheliumdependent-relaxation-in-aorta-of-mice-with-overexpression-of-hyaluronan-in-tunica-media(7c2129cc-df94-4736-bcfc-173fee213736).html
Autor:
Hui Chen, Song Chai, Karen Axelgaard Lorentzen, Ulf Simonsen, Lise Wogensen, Carl Christian Danielsen
Publikováno v:
Lorentzen, K A, Chai, S, Chen, H, Danielsen, C C, Simonsen, U & Wogensen, L 2016, ' Mechanisms involved in extracellular matrix remodeling and arterial stiffness induced by hyaluronan accumulation ', Atherosclerosis, vol. 244, pp. 195-203 . https://doi.org/10.1016/j.atherosclerosis.2015.11.016
Background and aims Hyperglycemia induces hyaluronan (HA) accumulation in the vasculature. Excessive accumulation of HA around the vascular smooth muscle cells (VSMC) results in increased aortic stiffness and strength and accelerated atherosclerosis
Autor:
Dorte Aalund Olsen, Ivan Brandslund, Karen Axelgaard Lorentzen, Karen-Lise Garm Spindler, Jan Lindebjerg, Torben Hansen, Rikke Fredslund Andersen, Anders Jakobsen
Publikováno v:
Hansen, T F, Spindler, K-L G, Lorentzen, K A, Olsen, D A, Andersen, R F, Lindebjerg, J, Brandslund, I & Jakobsen, A 2010, ' The importance of-460 C/T and +405 G/C single nucleotide polymorphisms to the function of vascular endothelial growth factor A in colorectal cancer ', Journal of Cancer Research and Clinical Oncology, vol. 136, no. 5, pp. 751-8 . https://doi.org/10.1007/s00432-009-0714-1
Hansen, T F, Spindler, K-L G, Lorentzen, K A, Olsen, D A, Andersen, R F, Lindebjerg, J, Brandslund, I & Jakobsen, A 2009, ' The importance of-460 C/T and +405 G/C single nucleotide polymorphisms to the function of vascular endothelial growth factor A in colorectal cancer ', Journal of Cancer Research and Clinical Oncology, vol. 136, no. 5, pp. 751-758 . https://doi.org/10.1007/s00432-009-0714-1
Hansen, T F, Spindler, K-L G, Lorentzen, K A, Olsen, D A, Andersen, R F, Lindebjerg, J, Brandslund, I & Jakobsen, A 2009, ' The importance of-460 C/T and +405 G/C single nucleotide polymorphisms to the function of vascular endothelial growth factor A in colorectal cancer ', Journal of Cancer Research and Clinical Oncology, vol. 136, no. 5, pp. 751-758 . https://doi.org/10.1007/s00432-009-0714-1
Udgivelsesdato: 2009-Nov-11 PURPOSE: The present study investigated the functional influence of the single nucleotide polymorphisms (SNPs) -460 C/T and +405 G/C at vascular endothelial growth factor A (VEGF-A), mRNA and protein levels in colorectal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edce1d56f3da7a35e23ac5f2c32c474f
https://pure.au.dk/portal/da/publications/the-importance-of-460-ct-and-405-gc-single-nucleotide-polymorphisms-to-the-function-of-vascular-endothelial-growth-factor-a-in-colorectal-cancer(b89435b7-0576-4454-8a1b-001a70acdffc).html
https://pure.au.dk/portal/da/publications/the-importance-of-460-ct-and-405-gc-single-nucleotide-polymorphisms-to-the-function-of-vascular-endothelial-growth-factor-a-in-colorectal-cancer(b89435b7-0576-4454-8a1b-001a70acdffc).html
Autor:
Torben Hansen, Ivan Brandslund, Karen-Lise Garm Spindler, Anders Jakobsen, Dorte Aalund Olsen, Jan Lindebjerg, Karen Axelgaard Lorentzen, Rikke Fredslund Andersen
Publikováno v:
Hansen, T F, Garm Spindler, K-L, Olsen, D A, Andersen, R F, Lindebjerg, J, Brandslund, I, Jakobsen, A & Lorentzen, K A 2009, ' Quantitative analysis of vascular endothelial growth factor receptors 1 and 2 in colorectal cancer ', Molecular Medicine Reports, vol. 2, no. 5, pp. 787-792 . https://doi.org/10.3892/mmr_00000173
Vascular endothelial growth factor A (VEGF-A) is a key regulator of angiogenesis that binds to the receptors VEGFR-1 and VEGFR-2. It is well known that VEGF-A levels are increased in colorectal cancer (CRC) tissue compared to normal colorectal tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fcf2df1ce466038bf4b7af3def2af34
https://pure.au.dk/portal/da/publications/quantitative-analysis-of-vascular-endothelial-growth-factor-receptors-1-and-2-in-colorectal-cancer(303639e9-4859-400f-b659-8205b77575d9).html
https://pure.au.dk/portal/da/publications/quantitative-analysis-of-vascular-endothelial-growth-factor-receptors-1-and-2-in-colorectal-cancer(303639e9-4859-400f-b659-8205b77575d9).html
Autor:
Karen Axelgaard Lorentzen, Karina Dahl Steffensen, Hans Jørgen Knudsen, Dorte Aalund Olsen, Ivan Brandslund, Thomas J. Corydon, Anders Jakobsen, Ulla Jeppesen, Marianne Waldstrøm
Publikováno v:
Steffensen, K D, Waldstrøm, M, Olsen, D A, Corydon, T, Lorentzen, K A, Knudsen, H J, Jeppesen, U, Brandslund, I & Jakobsen, A 2008, ' Mutant epidermal growth factor receptor in benign, borderline, and malignant ovarian tumors ', Clinical Cancer Research, vol. 14, no. 11, pp. 3278-3282 . https://doi.org/10.1158/1078-0432.CCR-07-4171
Steffensen, K D, Waldstrøm, M, Olsen, D A, Corydon, T, Lorentzen, K A, Knudsen, H J, Jeppesen, U, Brandslund, I & Jakobsen, A 2008, ' Mutant epidermal growth factor receptor in benign, borderline, and malignant ovarian tumors ', Clinical Cancer Research, vol. 14, no. 11, pp. 3278-82 . https://doi.org/10.1158/1078-0432.CCR-07-4171
Steffensen, K D, Waldstrøm, M, Olsen, D A, Corydon, T, Lorentzen, K A, Knudsen, H J, Jeppesen, U, Brandslund, I & Jakobsen, A 2008, ' Mutant epidermal growth factor receptor in benign, borderline, and malignant ovarian tumors ', Clinical Cancer Research, vol. 14, no. 11, pp. 3278-82 . https://doi.org/10.1158/1078-0432.CCR-07-4171
Purpose: Dysfunction of the epidermal growth factor (EGF) complex is essential to the growth and development of many human tumors. Overexpression of the EGF receptor (EGFR) is a characteristic finding in a considerable number of solid tumors and ofte
Autor:
Torben Hansen, Karen-Lise Garm Spindler, Karen Axelgaard Lorentzen, Rikke Fredslund Andersen, Lone Frischknecht, John Pløen Mortensen, Ivan Brandslund, Anders Jakobsen
Publikováno v:
Hansen, T, Spindler, K-L G, Lorentzen, K A, Andersen, R F, Frischknecht, L, Mortensen, J P, Brandslund, I & Jakobsen, A 2008, ' The relationship between vascular endothelial growth factor A and-460 C/T and +405 G/C single nucleotide polymorphisms in colorectal cancer ', World Congress on Gastrointestinal Cancer at CCIB, Barcelona, Spain, 25/06/2008-28/06/2008 .
University of Southern Denmark
University of Southern Denmark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::35dc34a7ad330e3af361dd3d6661fce2
https://portal.findresearcher.sdu.dk/da/publications/9fcc0f30-4378-11dd-9fbe-000ea68e967b
https://portal.findresearcher.sdu.dk/da/publications/9fcc0f30-4378-11dd-9fbe-000ea68e967b
Autor:
Torben Hansen, Karen-Lise Garm Spindler, Karen Axelgaard Lorentzen, Dorte Aalund Olsen, Rikke Fredslund Andersen, Jan Lindebjerg, Ivan Brandslund, Anders Jakobsen
Publikováno v:
University of Southern Denmark
Hansen, T, Spindler, K-L G, Lorentzen, K A, Olsen, D A, Fredslund Andersen, R, Lindebjerg, J, Brandslund, I & Jakobsen, A 2009, ' Quantitative analysis of the vascular endothelial growth factor receptor 1 and 2 in colorectal cancer ', Molecular Medicine Reports, vol. 2, no. 5, pp. 787-792 .
Hansen, T, Spindler, K-L G, Lorentzen, K A, Olsen, D A, Fredslund Andersen, R, Lindebjerg, J, Brandslund, I & Jakobsen, A 2009, ' Quantitative analysis of the vascular endothelial growth factor receptor 1 and 2 in colorectal cancer ', Molecular Medicine Reports, vol. 2, no. 5, pp. 787-792 .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::333be3db2bfea83a7bc0acef6ebfec1b
https://portal.findresearcher.sdu.dk/en/publications/ed8a9400-30a6-11de-b0ce-000ea68e967b
https://portal.findresearcher.sdu.dk/en/publications/ed8a9400-30a6-11de-b0ce-000ea68e967b