Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Karen Andrinéia de Oliveira"'
Autor:
Laíse Figueiredo de Oliveira, Gabriela Godoy Poluceno, Tuane Bazanella Sampaio, Leandra Celso Constantino, Ana Paula Costa, Wagner Carbolin Martins, Tharine Dal-Cim, Karen Andrinéia de Oliveira, Fabiana Kalyne Ludka, Rui Daniel Prediger, Frederico C. Pereira, Carla Inês Tasca
Publikováno v:
Neurotoxicity research.
Neonatal exposure to general anesthetics has been associated with neurotoxicity and morphologic changes in the developing brain. Isoflurane is a volatile anesthetic widely used in pediatric patients to induce general anesthesia, analgesia, and periop
Autor:
Carmen Simioni, Gabriela Godoy Poluceno, Marcelo Maraschin, Da Silva Pescador Gabriel, Ricardo Castilho Garcez, Roberto Bianchini Derner, Carla I. Tasca, Cláudia Beatriz Nedel, Karen Andrinéia de Oliveira, Rafael Garcia Lopes, Flavia Garcia Lopes, Claudia Marlene Bauer
Publikováno v:
Anticancer Research. 40:6799-6815
Background/aim Glioblastomas (GBMs) are the most malignant primary brain tumor. New treatment strategies against the disease are urgently needed, as therapies are not completely efficient. In this study, we evaluated the antitumorigenic activity of t
Autor:
Carla I. Tasca, Karen Andrinéia de Oliveira, Cláudia Beatriz Nedel, Gabriela Godoy Poluceno, Tharine Dal-Cim, Débora Lanznaster
Publikováno v:
Purinergic Signalling. 15:465-476
Glial cells are involved in multiple cerebral functions that profoundly influence brain tissue viability during ischemia, and astrocytes are the main source of extracellular purines as adenosine and guanosine. The endogenous guanine-based nucleoside
Autor:
Tharine Dal-Cim, Wagner C. Martins, Gabriela Godoy Poluceno, Frederico C. Pereira, Fabiana K. Ludka, Rui Daniel Prediger, Ana Paula Costa, Carla I. Tasca, Karen Andrinéia de Oliveira, Tuane Bazanella Sampaio, Laíse Figueiredo de Oliveira, Leandra C. Constantino
Publikováno v:
Neurotoxicity Research. 34:649-659
The neonatal exposure to general anesthetics has been associated with neuronal apoptosis and dendritic spines morphologic changes in the developing brain. Ketamine, a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, is widely used in p
Autor:
Andreza Fabro de Bem, Luiz Felipe de Souza, Alcir Luiz Dafre, Ariana Ern Schmitz, Carla I. Tasca, Marcelo Farina, Karen Andrinéia de Oliveira, Cláudia Beatriz Nedel, Luana Caroline da Silva
Publikováno v:
Toxicology in Vitro. 42:273-280
Thiol homeostasis has a critical role in the maintenance of proper cellular functions and survival, being coordinated by the action of several reductive enzymes, including glutathione (GSH)/glutathione reductase (GR) and thioredoxin (Trx)/thioredoxin
Autor:
Cláudia Beatriz Nedel, Carla I. Tasca, Karen Andrinéia de Oliveira, Flavia Garcia Lopes, Tharine Dal-Cim
Gliomas are a malignant tumor group whose patients have survival rates around 12 months. Among the treatments are the alkylating agents as temozolomide (TMZ), although gliomas have shown multiple resistance mechanisms for chemotherapy. Guanosine (GUO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4828a45057bb110d99c0362ee4cfa7c9
https://europepmc.org/articles/PMC5563291/
https://europepmc.org/articles/PMC5563291/
Autor:
Rosendo A. Yunes, Louise Domeneghini Chiaradia-Delatorre, Paulo César Leal, Artur Smânia, Carla I. Tasca, Claudia Beatriz Nedel Mendes de Aguiar, Alessandra Mascarello, Andréa L. Pimenta, Karen Andrinéia de Oliveira, Ricado José Nunes
Publikováno v:
International Journal of Antimicrobial Agents. 42:519-523
New unconventional approaches to the development of antimicrobial drugs must target inhibition of infection stages leading to host colonisation or virulence itself, rather than bacterial viability. Amongst the most promising unconventional targets fo
Autor:
Michel Fleith Otuki, Luiz Renato Olchanheski Junior, Daniel Fernandes, Regina Sordi, Natália Tambelline, Giovani Marino Favero, Karen Andrinéia de Oliveira
Publikováno v:
Brazilian Archives of Biology and Technology, Vol 55, Iss 2, Pp 263-268 (2012)
Brazilian Archives of Biology and Technology v.55 n.2 2012
Brazilian Archives of Biology and Technology
Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
Brazilian Archives of Biology and Technology, Volume: 55, Issue: 2, Pages: 263-268, Published: APR 2012
ResearcherID
Brazilian Archives of Biology and Technology v.55 n.2 2012
Brazilian Archives of Biology and Technology
Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
Brazilian Archives of Biology and Technology, Volume: 55, Issue: 2, Pages: 263-268, Published: APR 2012
ResearcherID
The success of revascularization procedures is limited by recurrent stenosis, which is a narrowing of a blood vessels that results from neo-intimal hyperplasia. The renin-angiotensin-aldosterone system has been implicated in the pathogenesis of neo-i
Autor:
Karen Andrinéia de Oliveira, Carla I. Tasca, Rosendo A. Yunes, Tharine Dal-Cim, Carine Bropp Cardoso, Louise Domeneghini Chiaradia-Delatorre, Alessandra Mascarello, Cláudia Beatriz Nedel, Lucas Felipe Fernandes Bittencourt, Flavia Garcia Lopes, Sharbel Weidner Maluf, Ricardo Castilho Garcez
Publikováno v:
Chemico-biological interactions. 252
Glioblastoma multiforme is the main and most frequent tumor in adults' central nervous system. With a survival average of 5% two years after diagnosis, this type of cancer is a main health problem. Substances like the chalcones have been tested in or
Autor:
Giordano Gubert Viola, Cláudia Beatriz Nedel Mendes-de-Aguiar, Rui Daniel Prediger, Karen Andrinéia de Oliveira, Carla I. Tasca, Samuel Vandresen-Filho, Alessandra Antunes dos Santos, Vanessa V. Santos, Marcelo Farina, Tharine Dal-Cim, Wagner C. Martins
Publikováno v:
Neurotoxicity research. 28(1)
Deposition of amyloid-β (Aβ) peptides into specific encephalic structures has been pointed as an important event related to Alzheimer's disease pathogenesis and associated with activation of glial cells, neuroinflammation, oxidative responses, and