Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Karen A. Bostian"'
Publikováno v:
FEBS Letters. 435:61-64
Type A botulinum neurotoxin (botox A) is a zinc metalloprotease that cleaves only one peptide bond in the synaptosomal protein, SNAP-25. Single-residue changes in a 17-residue substrate peptide were used to develop the first specific, competitive inh
Autor:
Karen A. Bostian, James J. Schmidt
Publikováno v:
Journal of Protein Chemistry. 16:19-26
Type A botulinum neurotoxin, a zinc-dependent endoproteinase that selectively cleaves the neuronal protein SNAP-25, can also cleave relatively short peptides. We found that bovine and other serum albumins stimulated the type A-catalyzed hydrolysis of
Publikováno v:
Environmental Toxicology and Chemistry. 10:5-8
The I-octanol/water partition coefficient (K,.) of methylmercury was determined at pH 7 in water and in aqueous solutions ranging from 0.0003 to 0.6000 m in sodium chloride. It was also determined over a pH range of 2 to 10 with a fixed sodium chlori
Autor:
James J. Schmidt, Karen A. Bostian
Publikováno v:
Journal of protein chemistry. 14(8)
Type A botulinum neurotoxin catalyzed the hydrolysis of synthetic peptides based on the sequence of the 25-kD synaptosomal protein SNAP-25. In each peptide, the toxin cleaved at a single glutaminyl-arginine bond corresponding to residues 197 and 198
Publikováno v:
Hospital Practice. 25:19-19
Publikováno v:
Biochemical Journal. 178:633-641
Daily intramuscular injections of clofibrate begun 6h before the initiation of inflammation induced by the subcutaneous injection of turpentine exerted a differential, dose-dependent inhibition of the anticipated acute-phase globulin response. Specif
Autor:
Robert W. Wannemacher, R S Pekarek, Karen A. Bostian, William R. Beisel, R. M. Kluge, Richard B. Hornick, Herbert L Dupont
Publikováno v:
Clinical Chemistry. 21:528-532
In volunteers experimentally infected with Salmonella typhi, serum iron and zinc concentrations became significantly depressed and there was a concomitant rise in serum copper before the onset of overt clinical illness. However, after several days of
Autor:
Clayton L. Hadick, Harold A. Neufeld, Robert W. Wannemacher, Richard E. Dinterman, Mitchell V. Kaminski, Karen A. Bostian
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 2:507-518
A model was developed in the rhesus monkey to determine if the marked wasting of body proteins associated with sepsis could be prevented by an intravenous supply of various nutritional substrates. All monkeys were given a basic infusion of 0.5 gm of
Publikováno v:
American Journal of Clinical Pathology. 57:506-510
Serum zinc concentrations were determined repeatedly in 99 healthy young men by a simple automated atomic absorption spectrophotometric method. The mean serum zinc concentration of these normal subjects was 102 μ g. per 100 ml. (SD = ±17), with a c