Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Karen A Heichman"'
Publikováno v:
Lancet Infect Dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf0bbcdfb9826359a912e9d788b287b
https://europepmc.org/articles/PMC8903051/
https://europepmc.org/articles/PMC8903051/
Publikováno v:
Clinica Chimica Acta. 438:358-363
Reliable methods that allow appropriate triage of women with an adnexal mass to a gynecologic oncologist are needed. We evaluated the clinical performance of OVA1 and ROMA for the prediction of malignancy in women with an adnexal mass.One hundred for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d8c70589217b2d7814cd6e009eef15
https://doi.org/10.1016/j.cca.2014.09.028
https://doi.org/10.1016/j.cca.2014.09.028
Publikováno v:
American Journal of Health Behavior. 38:351-361
Objectives To examine attitudes of a diverse community-based sample toward SEPT9, a simple, cost-effective colorectal cancer (CRC) blood test. Methods One-hundred participants eligible for CRC screening (Mage =58.3; 44% unscreened; 38% white, 31% His
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760873120dcb780b2d909d625a36e016
https://doi.org/10.5993/ajhb.38.3.4
https://doi.org/10.5993/ajhb.38.3.4
Autor:
Karen A. Heichman
Publikováno v:
Molecular Diagnosis & Therapy. 18:127-135
Colorectal cancer (CRC) is the third most common non-skin cancer diagnosed in men and women in the USA and worldwide. While it has been clearly established that screening for CRC, using a variety of methods, is cost effective and has a significant im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4fed32b6bac42c26529d6b91523f74
https://doi.org/10.1007/s40291-013-0074-z
https://doi.org/10.1007/s40291-013-0074-z
Autor:
Kathryn B. Horwitz, Karen A. Heichman, William P. Schiemann, Alana L. Welm, Douglas S. Micalizzi, J. Chuck Harrell, Kimberly L. Christensen, Heide L. Ford, Dean Billheimer, Anna E. Barón, Ricardo D. Coletta, Paul Jedlicka
Publikováno v:
Journal of Clinical Investigation. 119:2678-2690
Inappropriate activation of developmental pathways is a well-recognized tumor-promoting mechanism. Here we show that overexpression of the homeoprotein Six1, normally a developmentally restricted transcriptional regulator, increases TGF-β signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc67f262a1d1575c3c7b3f772c36b6f0
https://doi.org/10.1172/jci37815
https://doi.org/10.1172/jci37815
Autor:
Karen A. Heichman, James M. Roberts
Publikováno v:
Molecular Cell. 1(3):457-463
The Cdc28p cyclin-dependent kinase is thought to both catalyze the onset of DNA replication and prevent rereplication by blocking the reassembly of initiation complexes at replication origins. Budding yeast with mutations in the CDC16 gene represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe18a2ccd8dd9c0daaced2b8af001e0f
Autor:
Jinqiu Kuang, Scott K. Kuwada, Karen A. Heichman, Chad C. Nelson, Martin Majer, Yi Shen, Xiufen Li, Krishna Parsawar
Publikováno v:
The Journal of biological chemistry. 287(27)
Because HER-2 has been demonstrated in the nuclei of cancer cells, we hypothesized that it might interact with transcription factors that activate ERBB2 transcription. Macrohistone 2A1 (H2AFY; mH2A1) was found to interact with HER-2 in cancer cells t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f89ea142af830171c6b3719ba7840d0
https://pubmed.ncbi.nlm.nih.gov/22589551
https://pubmed.ncbi.nlm.nih.gov/22589551
Autor:
Karen A Heichman, Jorja D Warren
Publikováno v:
Clinical Chemistry and Laboratory Medicine. 50
Cellular DNA undergoes profound changes in methylation during cancer development, with hypermethylation occurring in specific gene promoters, amidst a backdrop of generalized hypomethylation. DNA methylation in cancer often causes the silencing of tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ac8a96aaec8f26bfbaa64794727fe1
https://doi.org/10.1515/cclm-2011-0935
https://doi.org/10.1515/cclm-2011-0935
Autor:
Wei Xiong, Karen A. Heichman, Larissa V. Furtado, Cecily P. Vaughn, Ashley M. Bunker, Wade S. Samowitz, William L. Roberts, John C. Fang, Jorja D Warren
Publikováno v:
BMC Medicine, Vol 9, Iss 1, p 133 (2011)
BMC Medicine
BMC Medicine
Background About half of Americans 50 to 75 years old do not follow recommended colorectal cancer (CRC) screening guidelines, leaving 40 million individuals unscreened. A simple blood test would increase screening compliance, promoting early detectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee1e01006ea30c4f3cf969df8b5ba09
https://doi.org/10.1186/1741-7015-9-133
https://doi.org/10.1186/1741-7015-9-133
Autor:
Ritsuko Iwanaga, Erica L McCoy, Lewis A. Chodosh, Heide L. Ford, Karen A. Heichman, Nee Shamo Abbey, Paul Jedlicka, Alana L. Welm
Six1 is a developmentally regulated homeoprotein with limited expression in most normal adult tissues and frequent misexpression in a variety of malignancies. Here we demonstrate, using a bitransgenic mouse model, that misexpression of human Six1 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c7fbced63d12b9992cde919ab8d37e
https://europepmc.org/articles/PMC2735909/
https://europepmc.org/articles/PMC2735909/