Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Karen A Boehme"'
Autor:
Sabine B Schleicher, Julian J Zaborski, Rosa Riester, Natascha Zenkner, Rupert Handgretinger, Torsten Kluba, Frank Traub, Karen A Boehme
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178857 (2017)
Rhabdomyosarcomas (RMS) are the most prevalent soft tissue sarcomas affecting children and adolescents. Despite intensive treatment consisting of multimodal chemotherapy and surgery RMS patients diagnosed with metastatic disease expect long term surv
Externí odkaz:
https://doaj.org/article/0b8e17f482364855af5524593e5cb6fe
Autor:
Selin Guergan, Bettina Boeer, Regina Fugunt, Gisela Helms, Carmen Roehm, Anna Solomianik, Alexander Neugebauer, Daniela Nuessle, Mirjam Schuermann, Kristin Brunecker, Ovidiu Jurjut, Karen A. Boehme, Sascha Dammeier, Markus D. Enderle, Sabrina Bettio, Irene Gonzalez-Menendez, Annette Staebler, Sara Y. Brucker, Bernhard Kraemer, Diethelm Wallwiener, Falko Fend, Markus Hahn
Publikováno v:
Diagnostics, Vol 14, Iss 3, p 338 (2024)
Breast conserving resection with free margins is the gold standard treatment for early breast cancer recommended by guidelines worldwide. Therefore, reliable discrimination between normal and malignant tissue at the resection margins is essential. In
Externí odkaz:
https://doaj.org/article/67d382e6de984874b27c584118bc7429
Autor:
Sabine Schleicher, Stefan Grote, Elke Malenke, Kenneth Chun-Ho Chan, Martin Schaller, Birgit Fehrenbacher, Rosa Riester, Torsten Kluba, Leonie Frauenfeld, Hans Boesmueller, Gudrun Göhring, Brigitte Schlegelberger, Rupert Handgretinger, Hans-Georg Kopp, Frank Traub, Karen A. Boehme
Publikováno v:
Cells, Vol 9, Iss 12, p 2668 (2020)
Sclerosing spindle cell rhabdomyosarcoma (SSRMS) is a rare rhabdomyosarcomas (RMS) subtype. Especially cases bearing a myogenic differentiation 1 (MYOD1) mutation are characterized by a high recurrence and metastasis rate, often leading to a fatal ou
Externí odkaz:
https://doaj.org/article/fd2b7cf0108b48bf81274a0d31f7d596
Autor:
Karen A Boehme, Rosa Riester, Frank Traub, Julia E Lenz, Rupert Handgretinger, Sabine Schleicher
Publikováno v:
Oncology Reports.
Ewing sarcomas (ES) are highly malignant mesenchymal tumors, which most often occur in children and adolescents. The current treatment of choice comprises wide resection in combination with multimodal chemotherapy including etoposide (Eto). Due to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3267a522d77a75955602e8c3ce215531
https://doi.org/10.3892/or.2019.7409
https://doi.org/10.3892/or.2019.7409
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 1, p 311 (2018)
Unlike other malignant bone tumors including osteosarcomas and Ewing sarcomas with a peak incidence in adolescents and young adults, conventional and dedifferentiated chondrosarcomas mainly affect people in the 4th to 7th decade of life. To date, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::daa1bf73399bf687dc64cb9d3971acfd
http://www.mdpi.com/1422-0067/19/1/311
http://www.mdpi.com/1422-0067/19/1/311
Autor:
Frank Traub, Julian J. Zaborski, Torsten Kluba, Karen A Boehme, Rosa Riester, Sabrina K. Schweiss, Sabine Schleicher, Ulrike Hopp, Rupert Handgretinger
Publikováno v:
International Journal of Oncology. 48:801-812
Rhabdomyosarcomas (RMS) are soft tissue tumours treated with a combination of surgery and chemotherapy. However, mortality rates remain high in case of recurrences and metastatic disease due to drug resistance and failure to undergo apoptosis. Theref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d496f4f0b0bbbb644d5ff055397dfdfb
https://doi.org/10.3892/ijo.2015.3293
https://doi.org/10.3892/ijo.2015.3293
Publikováno v:
International Journal of Molecular Sciences
Unlike other malignant bone tumors including osteosarcomas and Ewing sarcomas with a peak incidence in adolescents and young adults, conventional and dedifferentiated chondrosarcomas mainly affect people in the 4th to 7th decade of life. To date, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62b6583475550cc0d3fe1678630c4f3e
https://pubmed.ncbi.nlm.nih.gov/29361725
https://pubmed.ncbi.nlm.nih.gov/29361725
Autor:
Karen A Boehme, Frank Traub, Sabine Schleicher, Juliane Nitsch, Rupert Handgretinger, Torsten Kluba, Rosa Riester
Publikováno v:
International journal of oncology. 49(5)
Ewing sarcomas (ES) are rare mesenchymal tumours, most commonly diagnosed in children and adolescents. Arsenic trioxide (ATO) has been shown to efficiently and selectively target leukaemic blasts as well as solid tumour cells. Since multidrug resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20703da9913e281d144f9f2b2454c899
https://pubmed.ncbi.nlm.nih.gov/27665785
https://pubmed.ncbi.nlm.nih.gov/27665785
Autor:
Miriam Rothdiener, Miriam Hegemann, Tatiana Uynuk-Ool, Brandan Walters, Piruntha Papugy, Phong Nguyen, Valentin Claus, Tanja Seeger, Ulrich Stoeckle, Karen A. Boehme, Wilhelm K. Aicher, Jan P. Stegemann, Melanie L. Hart, Bodo Kurz, Gerd Klein, Bernd Rolauffs
Publikováno v:
Scientific Reports
Using matrix elasticity and cyclic stretch have been investigated for inducing mesenchymal stromal cell (MSC) differentiation towards the smooth muscle cell (SMC) lineage but not in combination. We hypothesized that combining lineage-specific stiffne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8f78ca1c2960cd8d3949cf3bdf0f5be2
https://pubmed.ncbi.nlm.nih.gov/27775041
https://pubmed.ncbi.nlm.nih.gov/27775041
Autor:
Christine Blattner, Karen A. Boehme
Publikováno v:
Current Chemical Biology. 4:1-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::386a12635307bf028b62d5edb693a7cf
https://doi.org/10.2174/187231310790226242
https://doi.org/10.2174/187231310790226242