Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Karen A, Urtishak"'
Autor:
Blaine W. Robinson, John A. Kairalla, Meenakshi Devidas, Andrew J. Carroll, Richard C. Harvey, Nyla A. Heerema, Cheryl L. Willman, Amanda R. Ball, Elliot C. Woods, Nancy C. Ballantyne, Karen A. Urtishak, Frederick G. Behm, Gregory H. Reaman, Joanne M. Hilden, Bruce M. Camitta, Naomi J. Winick, Jeanette Pullen, William L. Carroll, Stephen P. Hunger, ZoAnn E. Dreyer, Carolyn A. Felix
Publikováno v:
Haematologica, Vol 108, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/a81f0f0ee683429b9b3345bbb4014ff4
Autor:
Carolyn A. Felix, Patrizia Porazzi, Joanne M. Hilden, James W Davenport, Sarah K. Tasian, Meenakshi Devidas, ZoAnn E. Dreyer, Shenghao Jin, I-Ming L. Chen, Alix E. Seif, Tiffaney Vincent, Andrew J. Carroll, Martin Carroll, Blaine W. Robinson, Karen A. Urtishak, David T. Teachey, Katherine L. B. Borden, Biljana Culjkovic-Kraljacic, Stephen P. Hunger, Li-San Wang, Jeffrey S. Barrett, Jonni S. Moore, Richard C. Harvey, Nyla A. Heerema, Cheryl L. Willman
Publikováno v:
Oncogene
The poor outcomes in infant acute lymphoblastic leukemia (ALL) necessitate new treatments. Here we discover that EIF4E protein is elevated in most cases of infant ALL and test EIF4E targeting by the repurposed antiviral agent ribavirin, which has ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4fb9a36cc87b5cda83511517385570
http://europepmc.org/articles/PMC6440839
http://europepmc.org/articles/PMC6440839
Autor:
Li-San Wang, Margaret D. Sarezky, Jaclyn A. Biegel, Karen A. Urtishak, Donna Wilmoth, Julie W. Stern, Eric F. Rappaport, Carolyn A. Felix, Blaine W. Robinson, Kim E. Nichols
Publikováno v:
Pediatric Blood & Cancer. 63:1175-1180
Background Infant acute lymphoblastic leukemia (ALL) has never occurred in families except for the ∼100% concordant cases in monozygous twins attributed to twin-to-twin metastases. We report the first kindred with infant ALL in non-twin siblings. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ecdbec65590c23c0c666a30c644301f
https://doi.org/10.1002/pbc.25957
https://doi.org/10.1002/pbc.25957
Autor:
Carolyn A. Felix, James W Davenport, Neil Osheroff, Jo Ann W. Byl, Sager J. Gosai, Karen A. Urtishak, Eric F. Rappaport, Xiang Yu, Christos P. Kolaris, Brian D. Gregory, Marie L. Carillo
Type II topoisomerases orchestrate proper DNA topology, and they are the targets of anti-cancer drugs that cause treatment-related leukemias with balanced translocations. Here, we develop a high-throughput sequencing technology to define TOP2 cleavag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fa33186db28b20ebc7c14858d0487d
https://europepmc.org/articles/PMC5495075/
https://europepmc.org/articles/PMC5495075/
Autor:
Joanne M. Hilden, Andrew Bantly, Alena Y. Z. Edwards, Li-San Wang, Susan R. Atlas, Gregory H. Reaman, Nyla A. Heerema, Stephen P. Hunger, Blaine W. Robinson, Meenakshi Devidas, I-Ming L. Chen, Lori Cory, ZoAnn E. Dreyer, Amanda R. Hudome, Cheryl L. Willman, Andrew J. Carroll, Qian-Chun Yu, Carolyn A. Felix, Jeffrey S. Barrett, Karen A. Urtishak, Jonni S. Moore, Kajia Cao, Mondira Kundu
Publikováno v:
Blood. 121:2689-2703
Survival in infants younger than 1 year who have acute lymphoblastic leukemia (ALL) is inferior whether MLL is rearranged (R) or germline (G). MLL translocations confer chemotherapy resistance, and infants experience excess complications. We characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c01af0862bb285d4474cc71d02751c
https://doi.org/10.1182/blood-2012-04-425033
https://doi.org/10.1182/blood-2012-04-425033
Publikováno v:
Journal of Biological Chemistry. 284:5994-6003
Chromosomal abnormalities are frequently caused by problems encountered during DNA replication. Although the ATR-Chk1 pathway has previously been implicated in preventing the collapse of stalled replication forks into double-strand breaks (DSB), the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b600dbfd332cf8d00ec1738c221c1c0
https://doi.org/10.1074/jbc.m806739200
https://doi.org/10.1074/jbc.m806739200
Autor:
Karen A, Urtishak, Blaine W, Robinson, Eric F, Rappaport, Margaret D, Sarezky, Jaclyn A, Biegel, Kim E, Nichols, Donna M, Wilmoth, Li-San, Wang, Julie W, Stern, Carolyn A, Felix
Publikováno v:
Pediatric bloodcancer. 63(7)
Infant acute lymphoblastic leukemia (ALL) has never occurred in families except for the ∼100% concordant cases in monozygous twins attributed to twin-to-twin metastases. We report the first kindred with infant ALL in non-twin siblings. The siblings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a6f225e4d003f41aefa8bc8ae4e76145
https://pubmed.ncbi.nlm.nih.gov/26999444
https://pubmed.ncbi.nlm.nih.gov/26999444
Autor:
Nitzan Sternheim, Michael Choob, Steven A. Farber, Xiaobing Tian, J Archdeacon, S Talbot, V A Efimov, Eric Wickstrom, Karen A. Urtishak
Publikováno v:
Journal of Drug Targeting. 12:363-372
Morpholino phosphorodiamidate (MO) DNA mimics display excellent water solubility and hybridization properties toward DNA and RNA, and have been utilized in the model vertebrate zebrafish (Danio rerio) for genome-wide, sequence-based, reverse genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c444e1b6a04ed7ce7c80558f65d247c5
https://doi.org/10.1080/10611860412331285242
https://doi.org/10.1080/10611860412331285242
Publikováno v:
Pharmacology. 62:113-118
A series of phenylethanolamines bearing a 2-[1-phenylpropyl] substituent on the nitrogen atom was evaluated in vitro for activity at β1- and β2-adrenoceptors. As previously observed, the presence of 3,4-dihydroxy substitution on phenylethanolamine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f4b13ec99646181a07474686541e158
https://doi.org/10.1159/000056081
https://doi.org/10.1159/000056081
Autor:
F. Brad Johnson, Eric J. Brown, Rebecca A. Chanoux, Kevin D. Smith, Karen A. Urtishak, Roger A. Greenberg
Genome integrity is maintained during DNA replication by coordination of various replisome-regulated processes. Although it is known that Timeless (Tim) is a replisome component that participates in replication checkpoint responses to genotoxic stres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318865a25912438d1ea07e90fae1a16b
https://europepmc.org/articles/PMC2659236/
https://europepmc.org/articles/PMC2659236/