Zobrazeno 1 - 10 of 82 pro vyhledávání: '"Karen A, Gould"'
1
Akademický článek
Leukocytoclastic Vasculitis following the First Dose of the Elasomeran COVID-19 Vaccination
Autor: Jarett J. Casale, Mikél E. Muse, Tara J. Snow, Karen P. Gould, Natalie D. Depcik-Smith
Publikováno v: Case Reports in Dermatological Medicine, Vol 2022 (2022)
Our case highlights leukocytoclastic vasculitis as a potential side effect of the elasomeran COVID-19 vaccine. As the elasomeran vaccine becomes more widely available to the public, cutaneous reactions should be noted and looked for as potential side
Externí odkaz: https://doaj.org/article/82b71a19c4644cad90259c5057cf6e14
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2
Akademický článek
Estrogen Receptor Alpha Signaling Is Responsible for the Female Sex Bias in the Loss of Tolerance and Immune Cell Activation Induced by the Lupus Susceptibility Locus Sle1b
Autor: Jared H. Graham, Shayla D. Yoachim, Karen A. Gould
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
The dramatic female sex bias observed in human lupus is thought to be due, at least in part, to estrogens. Using mouse models, we have shown that estrogens, acting through estrogen receptor alpha (ERα) promote lupus development and contribute signif
Externí odkaz: https://doaj.org/article/eaf5c2eb0dff4b96b4d21c3e931cfad6
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6
Akademický článek
Evaluation of Rint1 as a modifier of intestinal tumorigenesis and cancer risk.
Autor: Karla L Otterpohl, Karen A Gould
Publikováno v: PLoS ONE, Vol 12, Iss 3, p e0172247 (2017)
The Rad50 Interacting Protein 1 (Rint1) influences cellular homeostasis through maintenance of endoplasmic reticulum, Golgi and centrosome integrity and regulation of vesicle transport, autophagy and the G2/M checkpoint. Rint1 has been postulated to
Externí odkaz: https://doaj.org/article/9dec28c42b4945d68ef2b4e525104d55
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7
Akademický článek
A dexamethasone prodrug reduces the renal macrophage response and provides enhanced resolution of established murine lupus nephritis.
Autor: Fang Yuan, Dana E Tabor, Richard K Nelson, Hongjiang Yuan, Yijia Zhang, Jenny Nuxoll, Kimberly K Bynoté, Subodh M Lele, Dong Wang, Karen A Gould
Publikováno v: PLoS ONE, Vol 8, Iss 11, p e81483 (2013)
We evaluated the ability of a macromolecular prodrug of dexamethasone (P-Dex) to treat lupus nephritis in (NZB × NZW)F1 mice. We also explored the mechanism underlying the anti-inflammatory effects of this prodrug. P-Dex eliminated albuminuria in mo
Externí odkaz: https://doaj.org/article/5ed0abc4a4504c2fbd2ff04d75d0ac4e
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8
Estrogen Receptor Alpha Signaling Is Responsible for the Female Sex Bias in the Loss of Tolerance and Immune Cell Activation Induced by the Lupus Susceptibility Locus Sle1b
Autor: Karen A. Gould, Shayla D. Yoachim, Jared H. Graham
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
The dramatic female sex bias observed in human lupus is thought to be due, at least in part, to estrogens. Using mouse models, we have shown that estrogens, acting through estrogen receptor alpha (ERα) promote lupus development and contribute signif
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c23cf1cdedb810fcdfad3799da0c1d0
https://doi.org/10.3389/fimmu.2020.582214
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10
An Lck–cre transgene accelerates autoantibody production and lupus development in (NZB × NZW)F1 mice
Autor: Richard K. Nelson, Karen A. Gould
Publikováno v: Lupus. 25:137-154
Lupus is an autoimmune disease characterized by the development of antinuclear autoantibodies and immune complex-mediated tissue damage. T cells in lupus patients appear to undergo apoptosis at an increased rate, and this enhanced T cell apoptosis ha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a89efb71329032a41a3594690b42de5
https://doi.org/10.1177/0961203315603139
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