Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Karen M. L. Morriss"'
Autor:
Rebecca H. Graves, Alan P. Hill, David E. Clapham, Steven L. Sollis, Karen M. L. Morriss, Robert J. Slack, Nick Barton, Ashley Paul Hancock, Heather Hobbs, Afjal Hussain Miah, Coline Jumeaux, Alison J. Ford, Claire E. Smith, Deborah Needham, Emma B. Sheriff, Panayiotis A. Procopiou, Simon Teanby Hodgson, John Barrett, Malcolm Begg, David A. Hall, Yannick M. L. Lacroix, Royston C. B. Copley, Hugo Staton
Publikováno v:
Journal of Medicinal Chemistry. 56:1946-1960
A series of indazole arylsulfonamides were synthesized and examined as human CCR4 antagonists. Methoxy- or hydroxyl-containing groups were the more potent indazole C4 substituents. Only small groups were tolerated at C5, C6, or C7, with the C6 analog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae8d8293ba0da5bc006f2fa7aeae3c0
https://doi.org/10.1021/jm301572h
https://doi.org/10.1021/jm301572h
Autor:
Linda J. Russell, Paul Martin Gore, Simon Teanby Hodgson, Ashley Paul Hancock, Robert J. Slack, Jennifer M. Buckley, Sadie Vile, Michael Kranz, Steven L. Sollis, Kenneth L. Clark, Brian Edgar Looker, Panayiotis A. Procopiou, Clarissa J. Watts, Duncan S. Holmes, Christopher Browning, Lise C. Fechner, Daniel L. Parton, Karen M. L. Morriss
Publikováno v:
Journal of medicinal chemistry. 54(7)
A series of potent phthalazinone-based human H(1) and H(3) bivalent histamine receptor antagonists, suitable for intranasal administration for the potential treatment of allergic rhinitis, were identified. Blockade of H(3) receptors is thought to imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ddea436df395618c79719086888815
https://pubmed.ncbi.nlm.nih.gov/21381763
https://pubmed.ncbi.nlm.nih.gov/21381763
Autor:
Gemma Victoria White, Helen E. Connor, Elizabeth Pickup, David Matthew Wilson, Clarissa J. Watts, Christopher Browning, Sanjeet Singh Sehmi, Karen M. L. Morriss, Mark James Bamford, Christopher A. Parr, Susannah Davies, Brian Edgar Looker, Panayiotis A. Procopiou, Simon Teanby Hodgson, Fogden Yvonne C, Rachael A. Ancliff, Woodrow Michael David, Duncan S. Holmes
Publikováno v:
Journal of medicinal chemistry. 50(26)
A series of ketopiperazines were prepared and evaluated for their activity as histamine H 3 antagonists. From investigation of the tertiary basic center in the aminopropyloxyphenyl template, the 2( R)-methylpyrrolidine was identified as the most pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379b02c58096cd697e1e8d0c03ea6702
https://pubmed.ncbi.nlm.nih.gov/18052318
https://pubmed.ncbi.nlm.nih.gov/18052318
Autor:
Panayiotis A. Procopiou, Rachael A. Ancliff, Mark J. Bamford, Christopher Browning, Helen Connor, Susannah Davies, Yvonne C. Fogden, Simon T. Hodgson, Duncan S. Holmes, Brian E. Looker, Karen M. L. Morriss, Christopher A. Parr, Elizabeth A. Pickup, Sanjeet S. Sehmi, Gemma V. White, Clarissa J. Watts, David M. Wilson, Michael D. Woodrow
Publikováno v:
Journal of Medicinal Chemistry; Nov2007, Vol. 50 Issue 26, p6706-6717, 12p