Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Karen, Oegema"'
Autor:
Jack Houston, Midori Ohta, J. Sebastián Gómez-Cavazos, Amar Deep, Kevin D. Corbett, Karen Oegema, Pablo Lara-Gonzalez, Taekyung Kim, Arshad Desai
Publikováno v:
Current Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29ba77c0aea0ef22196917e527818397
https://doi.org/10.1016/j.cub.2023.04.021
https://doi.org/10.1016/j.cub.2023.04.021
Autor:
Oliver Wueseke, David Zwicker, Anne Schwager, Yao Liang Wong, Karen Oegema, Frank Jülicher, Anthony A. Hyman, Jeffrey B. Woodruff
Publikováno v:
Biology Open, Vol 5, Iss 10, Pp 1431-1440 (2016)
Centrosomes are major microtubule-organizing centers composed of centrioles surrounded by an extensive proteinacious layer called the pericentriolar material (PCM). In Caenorhabditis elegans embryos, the mitotic PCM expands by Polo-like kinase 1 (PLK
Externí odkaz:
https://doaj.org/article/f3547410e3864e1b8030bb9daf87573b
Autor:
Renat N Khaliullin, Rebecca A Green, Linda Z Shi, J Sebastian Gomez-Cavazos, Michael W Berns, Arshad Desai, Karen Oegema
Publikováno v:
eLife, Vol 7 (2018)
To ensure timely cytokinesis, the equatorial actomyosin contractile ring constricts at a relatively constant rate despite its progressively decreasing size. Thus, the per-unit-length constriction rate increases as ring perimeter decreases. To underst
Externí odkaz:
https://doaj.org/article/0d52aaadbadb4c0ca0f25ecc3c1fa313
Autor:
Kian-Yong Lee, Rebecca A Green, Edgar Gutierrez, J Sebastian Gomez-Cavazos, Irina Kolotuev, Shaohe Wang, Arshad Desai, Alex Groisman, Karen Oegema
Publikováno v:
eLife, Vol 7 (2018)
Throughout metazoans, germ cells undergo incomplete cytokinesis to form syncytia connected by intercellular bridges. Gamete formation ultimately requires bridge closure, yet how bridges are reactivated to close is not known. The most conserved bridge
Externí odkaz:
https://doaj.org/article/8d54a258e8bc4974992ec3a275f36ca7
Autor:
Franz Meitinger, Robert L. Davis, Mallory B. Martinez, Andrew K. Shiau, Karen Oegema, Arshad Desai
Mitotic duration is tightly constrained, with extended mitotic duration being a characteristic of potentially problematic cells prone to chromosome missegregation and genomic instability. We show that memories of mitotic duration are integrated by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61a7fc24787cc425676bef14da42b365
https://doi.org/10.1101/2022.11.14.515741
https://doi.org/10.1101/2022.11.14.515741
Autor:
Jack Houston, Midori Ohta, J. Sebastián Gómez-Cavazos, Amar Deep, Kevin D. Corbett, Karen Oegema, Pablo Lara-Gonzalez, Taekyung Kim, Arshad Desai
During mitosis chromosomes assemble kinetochores in order to dynamically couple with spindle microtubules (Cheeseman, 2014; Musacchio & Desai, 2017). Kinetochores also function as signaling hubs directing mitotic progression by recruiting and control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16b55993a6245f7c91966ac3e5e55ead
https://doi.org/10.1101/2022.10.07.511323
https://doi.org/10.1101/2022.10.07.511323
Publikováno v:
eLife, Vol 6 (2017)
A protein called SAS-7 is required for daughter centrioles to become mothers in C. elegans.
Externí odkaz:
https://doaj.org/article/eaa4b29488804be4868d654ac622fadd
Publikováno v:
Cell Reports, Vol 9, Iss 3, Pp 874-883 (2014)
Precise regulation of microtubule (MT) dynamics is increasingly recognized as a critical determinant of axon regeneration. In contrast to developing neurons, mature axons exhibit noncentrosomal microtubule nucleation. The factors regulating noncentro
Externí odkaz:
https://doaj.org/article/6f8a63924b604ed0803ee032a347a5e4
Autor:
Pablo Lara-Gonzalez, Christian O. De Groot, Andrew K. Shiau, Arshad Desai, Jack Houston, Joost Monen, Adina Gerson-Gurwitz, Karen Oegema, Bethany Davis
Publikováno v:
Molecular Biology of the Cell. 32:1193-1201
Caenorhabditis elegans builds centromeres using the histone H3 variant CENP-A but lacks a CENP-A-specific chaperone. This article shows that the extended N-terminal tail of C. elegans CENP-A, which interacts with the conserved loading factor KNL-2 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d92fa5f26e311c5361f3c09c5c80572d
https://doi.org/10.1091/mbc.e20-12-0798
https://doi.org/10.1091/mbc.e20-12-0798
Publikováno v:
Science
Science (New York, N.Y.), vol 371, iss 6524
Science (New York, N.Y.), vol 371, iss 6524
Checking fidelity in cell division Everything has to go right during cell division, so a checkpoint mechanism known as the spindle-assembly checkpoint prevents mitosis from proceeding unless the kinetochores that attach chromosomes to the spindle mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb47d24513a557ea90ceaa83654ff75
https://doi.org/10.1126/science.abc1424
https://doi.org/10.1126/science.abc1424