PAXX and Xlf interplay revealed by impaired CNS development and immunodeficiency of double KO mice

Autor: Ana Cumano, Benoit Roch, Laetitia Kermasson, Ramy Elsaid, Vincent Abramowski, Jean-Paul Moussu, Olivier Etienne, Aurélie Berland, Jean-Pierre de Villartay, Stefania Musilli, Patrick Revy, Junjie Yang, François D. Boussin, Karelia Lipson-Ruffert

Publikováno v: Cell Death and Differentiation
Cell Death and Differentiation, 2018, 25 (2), pp.444-452. ⟨10.1038/cdd.2017.184⟩
Cell Death and Differentiation, Nature Publishing Group, 2018, 25 (2), pp.444-452. ⟨10.1038/cdd.2017.184⟩

International audience; The repair of DNA double-stranded breaks (DNAdsb) through non-homologous end joining (NHEJ) is a prerequisite for the proper development of the central nervous system and the adaptive immune system. Yet, mice with Xlf or PAXX

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3cc9d04ecd1382b0369f5c36141e99
https://europepmc.org/articles/PMC5762856/