Výsledky vyhledávání - "Karelia Cosme"

Akademický článek

Establishment of an in vivo potency assay for the recombinant hepatit is B surface antigen in monovalent and combined vaccines

Autor: Mabel Izquierdo-López, Karelia Cosme-Diaz, Gerardo García-Illera, Zoe Núñez-Lamotte, Yamila Martínez- Cuéllar, Maribel Vega-Simón, Lourdes Costa-Anguiano, Marisel Quintana-Esquivel, Ileana Rosales-Torres, Omar Mosqueda-Lobaina

Publikováno v: VacciMonitor, Vol 23, Iss 3, Pp 83-90 (2014)

In this paper the development of potency assay in animals (mice) was made, with the objective of demonstrating the immunogenic power of the recombinant Hepatitis B surface antigen in monovalent and combined vaccines, produced at the Center of Genet

Externí odkaz: https://doaj.org/article/0a3b62f1032e4bc98a90d6ab69948146

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Akademický článek

Effect of human epidermal growth factor on the tumor cell line A431: in vivo analysis of tumor growth inhibition and gene expression

Autor: Isabel A Guillén, Hanlet Camacho, Maria E Fernández, Daniel O Palenzuela, Lincidio Pérez, Maria E Ochagavia, Julio Ancizar, Angela Tuero, Laritza Gorovaya, Osmani Mendoza, Tamara Díaz, Julio R Fernández, Juan Roca, Karelia Cosme, Gerardo E Guillén-Nieto, Luis Herrera, Jorge Berlanga, Lidia I Novoa

Publikováno v: Biotecnología Aplicada, Vol 29, Iss 3, Pp 155-161

The historical tag of the epidermal growth factor (EGF) as carcinogenesis promoter has not been uniformly reproduced, since, in some experiments, malignant cells are bound to growth inhibition and apoptosis. The present study intends to obtain additi

Externí odkaz: https://doaj.org/article/b820ce1cdec34b21a6716e85750a8e62

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Akademický článek

Growth Hormone Releasing Peptide 6 (GHRP6) reduces liver fibrosis in CCl4 chronically intoxicated rats

Publikováno v: Biotecnología Aplicada, Vol 29, Iss 2, Pp 60-72

Tissue fibrosis is a leading cause of morbidity and mortality. Current treatments for conditions such as hepatic fibrosis have been unsuccessful. The growth hormone relasing peptide 6 (GHRP6) is endowed with cardioprotective actions but its antifibro

Externí odkaz: https://doaj.org/article/6312de42be364b7fbd319f6cf96961e7

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Akademický článek

Molecular mechanisms involved in the inhibition of tumor cells proliferation exposed to elevated concentrations of the epidermal growth factor

Publikováno v: Biotecnología Aplicada, Vol 30, Iss 3, Pp 223-227

The EGF promotes inhibition of cell proliferation in vitro and in vivo models depending on its concentration, application schema and the type of tumor cells on which it acts. Our research hypothesis was based on the fact that the EGF varies the expre

Externí odkaz: https://doaj.org/article/f7130c5615ef43bd916021f949df8f1b

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Akademický článek

Preclinical safety testing of the Quimi-Hib(r) vaccine adjuvanted with aluminum phosphate during product development

Autor: Dania Bacardí, Karelia Cosme, Lizet Aldana, Nelson Merino, José Suárez, Omar Mosqueda, Dioslaida Urquiza, Juan Romero, Roberto Madrigal, Rubén Amaya, Lourdes Hernández

Publikováno v: Biotecnología Aplicada, Vol 30, Iss 2, Pp 118-124

Haemophilus influenzae type b (Hib) is a Gram-negative bacterium causing diseases such as meningitis, pneumonia, epiglottis, cellulitis, septicemia and arthritis, among others. Hib-caused meningitis / Hib meningitis is a very serious disease with a d

Externí odkaz: https://doaj.org/article/010cc45f54d04f42a98b97cc9dc5a049

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Akademický článek

CIGB-247 vaccine breaks immunological tolerance to the vascular endothelial growth factor in mice, rats, rabbits and non-human primates, without disturbing physiologic angiogenic processes

Autor: Yanelys Morera, Mónica Bequet, Marta Ayala, Jorge V Gavilondo, Jorge Castro, Pedro Puente, Julio Ancízar, José Suarez, Javier Sanchez, Karelia Cosme, Dania Bacardí, Boris E Acevedo

Publikováno v: Biotecnología Aplicada, Vol 29, Iss 2, Pp 118-121

CIGB-247 is a novel cancer therapeutic vaccine that uses a mutated form of human vascular endothelial growth factor (VEGF) as antigen in combination with the oil-free adjuvant VSSP (very small sized proteoliposomes of Neisseria meningitidis outer mem

Externí odkaz: https://doaj.org/article/112aa2f7c1824ec9a6d1da43bbe64aa2

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Akademický článek

Therapeutic effect of two altered peptide ligands derived from the human heat shock protein 60 in experimental models of rheumatoid arthritis

Autor: María del C Domínguez, Norailys Lorenzo, Ariana Barberá, Gabriel Padrón, Ana María Torres, María V Hernández, Isabel Hernández, Rafael Gil, Aniel Sánchez, Vladimir Besada, Luis J González, Hilda Garay, Osvaldo Reyes, Ever Pérez, Matilde López, Yuliet Mazola, Karelia Cosme, Julio Ancizar

Publikováno v: Biotecnología Aplicada, Vol 30, Iss 2, Pp 153-156

Induction of immune tolerance as therapeutic approach for autoimmune diseases constitutes a current research focal point. In this sense, two Altered Peptide Ligands (APLs) were evaluated for the induction of peripheral tolerance in patients with Rheu

Externí odkaz: https://doaj.org/article/59ce7c37291c4fe189b0f7dbe1f3c105

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