Effects of a hexokinase II deletion on the dynamics of glycolysis in continuous cultures ofSaccharomyces cerevisiae

Autor: M. Joost Teixeira de Mattos, Arthur L. Kruckeberg, Karel van Dam, Arthur Kuiper, Jan A. Berden, Léonie M. Raamsdonk, Jasper A. Diderich

Publikováno v: FEMS Yeast Research, 2, 165-172. Oxford University Press

In glucose-limited aerobic chemostat cultures of a wild-type Saccharomyces cerevisiae and a derived hxk2 null strain, metabolic fluxes were identical. However, the concentrations of intracellular metabolites, especially fructose 1,6-bisphosphate, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99818f01316fbf519600dbeb585e61dc
https://doi.org/10.1111/j.1567-1364.2002.tb00081.x

Functional analysis of the hexose transporter homologueHXT5 inSaccharomyces cerevisiae

Autor: J. Merijn Schuurmans, Monique van Gaalen, Karel van Dam, Jasper A. Diderich, Arthur L. Kruckeberg

Publikováno v: Yeast. 18:1515-1524

The HXT5 gene encodes a functional hexose transporter that has moderate affinity for glucose (Km=10 mM), moderate to low affinity for fructose (Km=40 mM) and low affinity for mannose (Km>100 mM). The sole presence of Hxt5p in an otherwise hexose tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28d216f338fd5ed593a5d75fa646e25c
https://doi.org/10.1002/yea.779

Hexokinase regulates kinetics of glucose transport and expression of genes encoding hexose transporters in Saccharomyces cerevisiae

Autor: Arthur L. Kruckeberg, Carlos Gancedo, Jasper A. Diderich, Karel van Dam, Thomas Petit

Publikováno v: Journal of Bacteriology, 182, 6815-6818. American Society for Microbiology
Petit, T, Diderich, J A, Kruckeberg, A L, Gancedo, C & van Dam, K 2000, ' Hexokinase regulates kinetics of glucose transport and expression of genes encoding hexose transporters in Saccharomyces cerevisiae. ', Journal of Bacteriology, vol. 182, pp. 6815-6818 . https://doi.org/10.1128/JB.182.23.6815-6818.2000

Glucose transport kinetics and mRNA levels of different glucose transporters were determined in Saccharomyces cerevisiae strains expressing different sugar kinases. During exponential growth on glucose, a hxk2 null strain exhibited high-affinity hexo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92bb50ad80ff61d818ce99a3751676aa
https://dare.uva.nl/personal/pure/en/publications/hexokinase-regulates-kinetics-of-glucose-transport-and-expression-of-genes-encoding-hexose-transporters-in-saccharomyces-cerevisiae(2020f9b8-11e0-4f4d-b133-46ed6787dc76).html

How do yeast cells sense glucose?

Autor: Michael C. Walsh, Arthur L. Kruckeberg, Karel van Dam

Publikováno v: BioEssays. 20:972-976

A glucose-sensing mechanism has been described in Saccharomyces cerevisiae that regulates expression of glucose transporter genes. The sensor proteins Snf3 and Rgt2 are homologous to the transporters they regulate. Snf3 and Rgt2 are integral plasma m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee3d4bb857778f653132194632d153e2
https://doi.org/10.1002/(sici)1521-1878(199812)20:12<972::aid-bies2>3.0.co

High-affinity glucose uptake in Saccharomyces cerevisiae is not dependent on the presence of glucose-phosphorylating enzymes

Autor: Hans Peter Smits, Pieter W. Postma, Karel Van Dam, Gertien J. Smits, Michael C. Walsh

Publikováno v: Yeast, 12, 439-447. John Wiley and Sons Ltd

Glucose uptake in Saccharomyces cerevisiae is believed to consist of two kinetically distinguishable components, the affinity of which is modulated during growth on glucose. It has been reported that triple hexose-kinase deletion mutants do not exhib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9c9f54fce19477d117d833eb9b1bd3
https://doi.org/10.1002/(sici)1097-0061(199604)12:5<439::aid-yea925>3.0.co