Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Karel eVales"'
Autor:
Tomáš ePetrásek, Martina eSkurlova, Kristyna eMaleninska, Iveta eVojtechova, Zdena eKristofikova, Hana eMatuskova, Jana eSirova, Karel eVales, Daniela eRipova, Ales eStuchlik
Publikováno v:
Frontiers in Aging Neuroscience, Vol 8 (2016)
Alzheimer´s disease (AD) is one of the most serious human, medical, and socioeconomic burdens. Here we tested the hypothesis that a rat model of Alzheimer´s disease (Samaritan; Taconic Pharmaceuticals, USA) based on the application of amyloid beta4
Externí odkaz:
https://doaj.org/article/ed994597a142420695391154543825cc
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
The involvement of the serotonin system in the pathophysiology of schizophrenia has been elucidated by experiments with hallucinogens. Application of a hallucinogen to humans leads to changes in perception, cognition, emotions and induction of psycho
Externí odkaz:
https://doaj.org/article/5e0ed951f03a4115b73ad593920cb671
Autor:
Karel eVales
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
A number of studies demonstrated a rapid onset of an antidepressant effect of non-competitive NMDA receptor antagonists. Nonetheless, its therapeutic potential is rather limited, due to a high coincidence of negative side-effects. Therefore, the chal
Externí odkaz:
https://doaj.org/article/573aa119910147d1918c6ced346259b9
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
Dopamine plays a role in generating flexible adaptive responses in changing environments. Chronic administration of D2-like agonist quinpirole (QNP) induces behavioral sensitization and stereotypical behaviors reminiscent of obsessive-compulsive diso
Externí odkaz:
https://doaj.org/article/629ec566a90141658a2c81dec5825d9b
Autor:
Tereza eNekovarova, Anna eYamamotova, Karel eVales, Ales eStuchlik, Jitka eFricova, Richard eRokyta
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
Neither pain, nor depression exist as independent phenomena per se, they are highly subjective inner states, formed by our brain and built on the bases of our experiences, cognition and emotions. Chronic pain is associated with changes in brain physi
Externí odkaz:
https://doaj.org/article/590b0761d55b445c833b6f58ce725c51
Autor:
Zdena eKristofikova, Monika eVrajova, Jana eSirova, Karel eVales, Tomas ePetrasek, Kai eSchönig, Bjorn eTews, Martin eSchwab, Dusan eBartsch, Ales eStuchlik, Daniela eRipova
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 7 (2013)
It has been suggested that Nogo-A, a myelin-associated protein, could play a role in the pathogenesis of schizophrenia and that Nogo-A-deficient rodents could serve as an animal model for schizophrenic symptoms. Since changes in brain laterality are
Externí odkaz:
https://doaj.org/article/a0565654a0644f3e96063028437c5668
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
Flexible behavior in dynamic, real-world environments requires more than static spatial learning and memory. Discordant and unstable cues must be organized in coherent subsets to give rise to meaningful spatial representations. We model this form of
Externí odkaz:
https://doaj.org/article/97a7c5b98bdd452e812d5ca727878e56