Zobrazeno 1 - 10
of 281
pro vyhledávání: '"Karel W A, Wirtz"'
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 40:227-235
Photolon™ is a photosensitiser with demonstrated potential as an anti-tumour agent. In this study, an in vitro investigation was performed to determine the mechanism of Photolon™-induced cell death. Cell killing was observed in a light-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f093d9b58c9a93d4067d51e5671cbf9d
https://doi.org/10.1016/j.biocel.2007.07.014
https://doi.org/10.1016/j.biocel.2007.07.014
Autor:
Karel W. A. Wirtz
Publikováno v:
FEBS Letters. 580:5436-5441
Since their discovery and subsequent purification from mammalian tissues more than 30 years ago an impressive number of studies have been carried out to characterize and elucidate the biological functions of phosphatidylcholine transfer protein (PC-T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd02c8dcc20e3c7336f71cb180647f5
https://doi.org/10.1016/j.febslet.2006.06.065
https://doi.org/10.1016/j.febslet.2006.06.065
Autor:
Freek L. van Muiswinkel, Gerry T. Snoek, Dop P. R. Bär, Peter Sodaar, Hanneke Bunte, Karel W. A. Wirtz, Martijn Schenning
Publikováno v:
Journal of Neurochemistry. 97:707-715
Selective neuronal loss is a prominent feature in both acute and chronic neurological disorders. Recently, a link between neurodegeneration and a deficiency in the lipid transport protein phosphatidylinositol transfer protein α (PI-TPα) has been de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7bc038390085e945371cf994781b7da
https://doi.org/10.1111/j.1471-4159.2006.03729.x
https://doi.org/10.1111/j.1471-4159.2006.03729.x
Publikováno v:
Advances in Enzyme Regulation. 46:301-311
Since their purification from bovine brain phosphatidylinositol transfer proteins (PI-TP) have been subject to extensive studies mainly prompted by the hypothesis that these proteins play a key role in intracellular phosphatidylinositol (PI) transpor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f1403033c28d27766f9f25d22b8d49d
https://doi.org/10.1016/j.advenzreg.2006.01.020
https://doi.org/10.1016/j.advenzreg.2006.01.020
Autor:
Peter Moonen, Robert Akeroyd, Petrus Smits, Karel W. A. Wirtz, Jan Westerman, Wouter C. Puijk
Publikováno v:
European Journal of Biochemistry. 106:279-290
The phosphatidylcholine exchange protein from bovine liver consists of a single polypeptide chain and has a blocked N terminus. The protein contains an estimated 244 amino acid residues in accordance with a determined molecular weight of 28000. The p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2440547e1c948814df9ef86113d8f38b
https://doi.org/10.1111/j.1432-1033.1980.tb06020.x
https://doi.org/10.1111/j.1432-1033.1980.tb06020.x
Autor:
Martijn Schenning, Barend M. Gadella, Gerry T. Snoek, Claudia M. van Tiel, Karel W. A. Wirtz, Jord C. Stam, Daniëlle van Manen
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 8, Pp 1555-1564 (2004)
Mouse fibroblast cells overexpressing phosphatidylinositol transfer protein α [PI-TPα; sense PI-TPα (SPIα) cells] show a significantly increased rate of proliferation and an extreme resistance toward ultraviolet- or tumor necrosis factor-α-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0bb1dac56fb49d8a0ceae80c99e4d7
http://www.sciencedirect.com/science/article/pii/S0022227520313183
http://www.sciencedirect.com/science/article/pii/S0022227520313183
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1636:151-158
Phosphatidylinositol transfer proteins (PI-TPs) consist of two isoforms (PI-TPalpha and PI-TPbeta), which differ in phospholipid transfer properties and intracellular localization. Both PI-TP isoforms are substrates for protein kinase C and contain a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4177e02405079884e79ead410748059d
https://doi.org/10.1016/j.bbalip.2003.08.009
https://doi.org/10.1016/j.bbalip.2003.08.009
Autor:
Johannes L. Bos, Nannette Jelluma, Karel W. A. Wirtz, Tobias B. Dansen, Ronald J.A. Wanders, Geert J. P. L. Kops, Simone Denis, Boudewijn M.T. Burgering
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 1, Pp 81-88 (2004)
Journal of lipid research, 45(1), 81-88. American Society for Biochemistry and Molecular Biology Inc.
Journal of lipid research, 45(1), 81-88. American Society for Biochemistry and Molecular Biology Inc.
The SCP gene encodes two proteins, sterol carrier protein X (SCPx) and SCP2, that are independently regulated by separate promoters. SCPx has been shown to be the thiolase involved in the breakdown of branched-chain fatty acids and in the biosynthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52575e973b1a2bad0ef2ac36a86b878e
http://www.sciencedirect.com/science/article/pii/S0022227520319234
http://www.sciencedirect.com/science/article/pii/S0022227520319234
Publikováno v:
European Journal of Biochemistry. 270:4859-4865
Photodynamic treatment (PDT) is an emerging therapeutic procedure for the management of cancer, based on the use of photosensitizers, compounds that generate highly reactive oxygen species (ROS) on irradiation with visible light. The ROS generated ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e35613b11b2fbd645c9864c8de3ce9e5
https://doi.org/10.1046/j.1432-1033.2003.03885.x
https://doi.org/10.1046/j.1432-1033.2003.03885.x
Publikováno v:
Biochemical Journal. 366:825-830
The membrane-permeable fluorescein-labelled tyramine conjugate (acetylTyrFluo) was used to identify the proteins of normal human dermal fibroblasts most susceptible to oxidation by hydrogen peroxide [Van der Vlies, Wirtz and Pap (2001) Biochemistry 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6935ab617b7bb60efaabc21032823671
https://doi.org/10.1042/bj20020618
https://doi.org/10.1042/bj20020618