Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Karel Smejkal"'
Autor:
Dana Dvorska, Alena Mazurakova, Lenka Lackova, Dominika Sebova, Karol Kajo, Marek Samec, Dusan Brany, Emil Svajdlenka, Jakub Treml, Sandra Mersakova, Jan Strnadel, Marian Adamkov, Zora Lasabova, Kamil Biringer, Jan Mojzis, Dietrich Büsselberg, Karel Smejkal, Martin Kello, Peter Kubatka
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionWithin oncology research, there is a high effort for new approaches to prevent and treat cancer as a life-threatening disease. Specific plant species that adapt to harsh conditions may possess unique properties that may be utilized in the
Externí odkaz:
https://doaj.org/article/712cfb8a7251426ca7c5229d02600bef
Autor:
Alena Mazurakova, Lenka Koklesova, Sandra Hurta Csizmár, Marek Samec, Aranka Brockmueller, Miroslava Šudomová, Kamil Biringer, Erik Kudela, Martin Pec, Samson Mathews Samuel, Monika Kassayova, Sherif T.S. Hassan, Karel Smejkal, Mehdi Shakibaei, Dietrich Büsselberg, Luciano Saso, Peter Kubatka, Olga Golubnitschaja
Publikováno v:
Journal of Advanced Research, Vol 55, Iss , Pp 103-118 (2024)
Background: Cancer management faces multiple obstacles, including resistance to current therapeutic approaches. In the face of challenging microenvironments, cancer cells adapt metabolically to maintain their supply of energy and precursor molecules
Externí odkaz:
https://doaj.org/article/8d1874c70909462aa7839fd64043bac5
Autor:
Peter Kubatka, Alena Mazurakova, Lenka Koklesova, Tomas Kuruc, Marek Samec, Karol Kajo, Klaudia Kotorova, Marian Adamkov, Karel Smejkal, Emil Svajdlenka, Dana Dvorska, Dusan Brany, Eva Baranovicova, Vladimira Sadlonova, Jan Mojzis, Martin Kello
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Based on extensive data from oncology research, the use of phytochemicals or plant-based nutraceuticals is considered an innovative tool for cancer management. This research aimed to analyze the oncostatic properties of Salvia officinal
Externí odkaz:
https://doaj.org/article/c3662297b57548de96e5359613f70678
Autor:
Anna Mascellani, Kirsten Leiss, Johanna Bac-Molenaar, Milan Malanik, Petr Marsik, Estuardo Hernandez Olesinski, Jan Tauchen, Pavel Kloucek, Karel Smejkal, Jaroslav Havlik
Publikováno v:
Frontiers in Plant Science, Vol 12 (2022)
Powdery mildew is a common disease affecting the commercial production of gerbera flowers (Gerbera hybrida, Asteraceae). Some varieties show a certain degree of resistance to it. Our objective was to identify biomarkers of resistance to powdery milde
Externí odkaz:
https://doaj.org/article/659ec200fc92499bb45f86063663bcf1
Autor:
Ondrej Vesely, Petr Marsik, Veronika Jarosova, Ivo Doskocil, Karel Smejkal, Pavel Kloucek, Jaroslav Havlik
Publikováno v:
Foods, Vol 10, Iss 11, p 2754 (2021)
2-arylbenzofurans represent a small group of bioactive compounds found in the plant family Moraceae. As it has not been investigated whether these substances are stable during passage through the gastrointestinal tract, their biological effects may b
Externí odkaz:
https://doaj.org/article/f4ca026d48844cb2ac1d365fba1e5b54
Autor:
Peter Kubatka, Martin Kello, Karol Kajo, Marek Samec, Karin Jasek, Desanka Vybohova, Sona Uramova, Alena Liskova, Vladimira Sadlonova, Lenka Koklesova, Radovan Murin, Marian Adamkov, Karel Smejkal, Emil Svajdlenka, Peter Solar, Samson Mathews Samuel, Monika Kassayova, Taeg Kyu Kwon, Pavol Zubor, Martin Pec, Jan Danko, Dietrich Büsselberg, Jan Mojzis
Publikováno v:
Molecules, Vol 25, Iss 6, p 1399 (2020)
Comprehensive oncology research suggests an important role of phytochemicals or whole plant foods in the modulation of signaling pathways associated with anticancer action. The goal of this study is to assess the anticancer activities of Cinnamomum z
Externí odkaz:
https://doaj.org/article/140f0feef961452d943dcd1b3c0423a1
Autor:
Karin Jasek, Peter Kubatka, Marek Samec, Alena Liskova, Karel Smejkal, Desanka Vybohova, Ondrej Bugos, Kristina Biskupska-Bodova, Tibor Bielik, Pavol Zubor, Jan Danko, Marian Adamkov, Taeg Kyu Kwon, Dietrich Büsselberg
Publikováno v:
Biomolecules, Vol 9, Iss 7, p 289 (2019)
The modulation of the activity of DNA methyltransferases (DNMTs) represents a crucial epigenetic mechanism affecting gene expressions or DNA repair mechanisms in the cells. Aberrant modifications in the function of DNMTs are a fundamental event and p
Externí odkaz:
https://doaj.org/article/119160cd92f84e0dbd1c87c10f3c89a2
Autor:
Veronika Jarosova, Ondrej Vesely, Petr Marsik, Jose Diogenes Jaimes, Karel Smejkal, Pavel Kloucek, Jaroslav Havlik
Publikováno v:
Molecules, Vol 24, Iss 6, p 1155 (2019)
Stilbenoids are dietary phenolics with notable biological effects on humans. Epidemiological, clinical, and nutritional studies from recent years have confirmed the significant biological effects of stilbenoids, such as oxidative stress protection an
Externí odkaz:
https://doaj.org/article/197792e486234cac975c6d2ce6427782
Autor:
Jose D. Jaimes, Veronika Jarosova, Ondrej Vesely, Chahrazed Mekadim, Jakub Mrazek, Petr Marsik, Jiri Killer, Karel Smejkal, Pavel Kloucek, Jaroslav Havlik
Publikováno v:
Molecules, Vol 24, Iss 4, p 744 (2019)
Dietary phenolics or polyphenols are mostly metabolized by the human gut microbiota. These metabolites appear to confer the beneficial health effects attributed to phenolics. Microbial composition affects the type of metabolites produced. Reciprocall
Externí odkaz:
https://doaj.org/article/7b8ce1ec502840c69b5984dd75605319
Publikováno v:
Molecules, Vol 12, Iss 6, Pp 1210-1219 (2007)
Paulownia tomentosa is a large indecidous tree planted mostly for its fast growing wood and decoratative purposes. The tree is also used in traditional Chinese medicine. As a part of our study of natural polyphenols, the fruits of Paulownia tomentosa
Externí odkaz:
https://doaj.org/article/8d8726824061485f9884fe19f51b63f4