Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Karel Šmejkal"'
Publikováno v:
ACS Omega, Vol 9, Iss 16, Pp 18023-18031 (2024)
Externí odkaz:
https://doaj.org/article/74733689ba1c4fd5bca481f255128c30
Autor:
Veronika Brezani, Nicolas Blondeau, Jan Kotouček, Eva Klásková, Karel Šmejkal, Jan Hošek, Eliška Mašková, Pavel Kulich, Vilailak Prachyawarakorn, Catherine Heurteaux, Josef Mašek
Publikováno v:
ACS Omega, Vol 9, Iss 8, Pp 9027-9039 (2024)
Externí odkaz:
https://doaj.org/article/a9089187a0de442b8e1164542fa4ce4c
Autor:
Michal Rybnikář, Milan Malaník, Karel Šmejkal, Emil Švajdlenka, Polina Shpet, Pavel Babica, Stefano Dall’Acqua, Ondřej Smištík, Ondřej Jurček, Jakub Treml
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3465 (2024)
Schisandra chinensis (Schisandraceae) is a medicinal plant widely used in traditional Chinese medicine. Under the name Wu Wei Zi, it is used to treat many diseases, especially as a stimulant, adaptogen, and hepatoprotective. Dibenzocyclooctadiene lig
Externí odkaz:
https://doaj.org/article/1d902858c38b415fa82ff06a2d8fcd2f
Autor:
Barbora Belakova, Nicholas K. Wedige, Ezzat M. Awad, Simon Hess, André Oszwald, Marlene Fellner, Shafaat Y. Khan, Ulrike Resch, Markus Lipovac, Karel Šmejkal, Pavel Uhrin, Johannes M. Breuss
Publikováno v:
Cells, Vol 12, Iss 24, p 2836 (2023)
Pre-clinical studies from the recent past have indicated that senescent cells can negatively affect health and contribute to premature aging. Targeted eradication of these cells has been shown to improve the health of aged experimental animals, leadi
Externí odkaz:
https://doaj.org/article/541bee0379d64455a4b0c42b2271e9bf
Autor:
Milan Malaník, Marie Čulenová, Alice Sychrová, Adrianna Skiba, Krystyna Skalicka-Woźniak, Karel Šmejkal
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1061 (2023)
Epilepsy is a neurological disease characterized by recurrent seizures that can lead to uncontrollable muscle twitching, changes in sensitivity to sensory perceptions, and disorders of consciousness. Although modern medicine has effective antiepilept
Externí odkaz:
https://doaj.org/article/933c216480b64914aca7232379e7072a
Autor:
Zdeněk Trávníček, Ján Vančo, Jan Belza, Jan Hošek, Zdeněk Dvořák, René Lenobel, Igor Popa, Karel Šmejkal, Pavel Uhrin
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2293 (2023)
Motivated by the clinical success of gold(I) metallotherapeutic Auranofin in the effective treatment of both inflammatory and cancer diseases, we decided to prepare, characterize, and further study the [Au(kin)(PPh3)] complex (1), where Hkin = kineti
Externí odkaz:
https://doaj.org/article/32e26e30bb4d41c08111dbac4ab39590
Publikováno v:
Molecules, Vol 27, Iss 1, p 166 (2021)
Plectranthus (Lamiaceae), which—according to the latest systematic revision—includes three separate genera (Coleus, Plectranthus sensu stricto, and Equilabium), is a genus widely used in traditional medicine—mainly in the treatment of various a
Externí odkaz:
https://doaj.org/article/065e688ece8747e79eeda8e9d41427e4
Publikováno v:
Potravinarstvo, Vol 11, Iss 1, Pp 223-229 (2017)
One of traditional plant that has so many pharmacology effects is chilli fruit (Capsicum sp.) that belong to the family Solanaceae. Around the world is known five varieties of Capsicum which are C. annuum, C. frutescens, C. chinense, C. baccatum, and
Externí odkaz:
https://doaj.org/article/4a548e13a4cb4bc2bb97e7814c471101
Publikováno v:
Molecules, Vol 26, Iss 9, p 2534 (2021)
Background: Oxidative stress is a key factor in the pathophysiology of many diseases. This study aimed to verify the antioxidant activity of selected plant phenolics in cell-based assays and determine their direct or indirect effects. Methods: The ce
Externí odkaz:
https://doaj.org/article/325419692fac43bd9c11aa364df7958f
Autor:
Sérgio M. Marques, Lucie Šupolíková, Lenka Molčanová, Karel Šmejkal, David Bednar, Iva Slaninová
Publikováno v:
Biomedicines, Vol 9, Iss 4, p 357 (2021)
Multidrug resistance (MDR) is a common problem when fighting cancer with chemotherapy. P-glycoprotein (P-gp, or MDR1) is an active pump responsible for the efflux of xenobiotics out of the cell, including anti-cancer drugs. It is a validated target a
Externí odkaz:
https://doaj.org/article/a182b1c303364c15b341910f28731058