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pro vyhledávání: '"Karel Kranda"'
Publikováno v:
Nuclear Physics News. 27:12-17
Nuclear physics applications in medicine and energy are well known and widely reported. For example, the recent report “Nuclear Physics for Medicine,” published by the European Science Foundation [...
Publikováno v:
Brain Pathol
Elevated concentrations of Zn, Cu and Fe, observed in biopsied or post‐mortem tissue from diseased human brains, have often been considered as some of the major factors in the etiology of excitotoxic neuronal death but without any direct evidence f
Autor:
Helena Svecova, Hana Chaloupkova, Daniel Seifert, Miroslav Fiser, Veronika Kleinova, Jörg Bäurle, Karel Kranda, Vlastimil Král
Publikováno v:
Applied Radiation and Isotopes. 66:310-316
The monoclonal antibody TU-20 and its scFv fragment were radiolabeled with 125I in order to develop new imaging agents against the specific neuronal marker III β-tubulin. The reaction via chloramine-T using thiosulfate as a stopping reductant was de
Publikováno v:
Czechoslovak Journal of Physics. 56:D683-D688
The ability of the monoclonal antibody TU-20 and its scFv fragment to specifically bind to the C-end of the class III beta-tubulin makes these preparations useful as potential diagnostics for in vivo determination of neurodegenerative diseases that e
Publikováno v:
Acta Neuropathologica. 112:691-702
Apoptosis as well as autophagy have been implicated in the death of cerebellar Purkinje cells (PCs) in the Lurcher (Lc/+) mutant mouse and at least two different apoptotic pathways participate in the transsynaptic death of granule cells (GC) and infe
Publikováno v:
Brain research bulletin. 71(1-3)
Cytochrome c translocation from the inner mitochondrial membrane into the cytosol is the initial step of the intrinsic apoptotic pathway. As no evidence was ever presented for cytochrome c translocation during cerebellar degeneration in Lurcher (Lc/+
Publikováno v:
Neuroscience letters. 372(1-2)
In this study, we searched for murine analogues of the four death-receptor types (TRAIL-R1 to R4), targeted by the tumour necrosis factor related apoptosis inducing ligand (TRAIL), which were recently identified in the human brain. The expression of
Publikováno v:
Sleep medicine. 4(5)
Background : Terguride as a partial D2-receptors agonist seems suitable for treatment of restless legs syndrome (RLS). Methods : Nine RLS patients without previous dopaminergic therapy received a daily dose of terguride (0.25 mg) 29.9±16.9 (SD) days
Autor:
Karel Kranda
Publikováno v:
Behavioral and Brain Sciences. 22:959-959
Palmer's attempt to dust off Locke's construct of “inverted spectrum” is discussed here to examine its plausibility. Perceptual inversion could be fulfilled by adopting the notion of “inverted trichromacy” rather than by the proposed existenc
Autor:
Karel Kranda, P. Ewen King-Smith
Publikováno v:
Vision research. 21(4)
Spectral sensitivity curves were measured for foveal test flashes at absolute threshold, and on varying intensities of a blue-white background which stimulates long and medium wave cones about equally. The average data for three subjects could be fit