Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Karel H. M. van Wely"'
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Background mRNA processing is an essential step of gene expression; its malfunction can lead to different degrees of physiological disorder from subclinical disease to death. We previously identified Dido1 as a stemness marker and a gene inv
Externí odkaz:
https://doaj.org/article/3be0f5320002462da9a1b2f29f19f012
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/4577dbd22cef433b99418ced3322d685
Autor:
Amaia Talavera-Gutiérrez, Ainhoa Sánchez de Diego, Thierry Fischer, Carlos Martínez-A, Carmen Mora Gallardo, Karel H. M. van Wely, Julio Gutiérrez Hernández
Publikováno v:
Nucleic Acids Research
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
© The Author(s) 2019.
Alternative splicing is facilitated by accessory proteins that guide spliceosome subunits to the primary transcript. Many of these splicing factors recognize the RNA polymerase II tail, but SFPQ is a notable exception even
Alternative splicing is facilitated by accessory proteins that guide spliceosome subunits to the primary transcript. Many of these splicing factors recognize the RNA polymerase II tail, but SFPQ is a notable exception even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f6c1d8708d559e6e2f97a07f4c73ed
https://doi.org/10.1093/nar/gkz235
https://doi.org/10.1093/nar/gkz235
Publikováno v:
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Transcription
article-version (VoR) Version of Record
Digital.CSIC. Repositorio Institucional del CSIC
instname
Consejo Superior de Investigaciones Científicas (CSIC)
Transcription
article-version (VoR) Version of Record
Digital.CSIC. Repositorio Institucional del CSIC
instname
Recent studies have identified multiple polyadenylation sites in nearly all mammalian genes. Although these are interpreted as evidence for alternative polyadenylation, our knowledge of the underlying mechanisms is still limited. Most studies only co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32550ee7c2769e754684314fcf2a8425
http://hdl.handle.net/10261/247621
http://hdl.handle.net/10261/247621
Autor:
W Martijn ter Haar, Magda A Meester-Smoor, Karel H M van Wely, Claudia C M M Schot, Marjolein J F W Janssen, Bart Geverts, Jacqueline Bonten, Gerard C Grosveld, Adriaan B Houtsmuller, Ellen C Zwarthoff
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46085 (2012)
The leukemia-associated fusion protein MN1-TEL combines the transcription-activating domains of MN1 with the DNA-binding domain of the transcriptional repressor TEL. Quantitative photobleaching experiments revealed that ∼20% of GFP-tagged MN1 and T
Externí odkaz:
https://doaj.org/article/d0f348eb9bb8484dbff8f98ebdb66193
Autor:
Magda A Meester-Smoor, Marjolein J F W Janssen, W Martijn ter Haar, Karel H M van Wely, Albert-Jan L H J Aarnoudse, Gertine van Oord, Gabrielle B A van Tilburg, Ellen C Zwarthoff
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e23620 (2011)
Retinoic acid receptor (RAR) signaling is important for regulating transcriptional activity of genes involved in growth, differentiation, metabolism and reproduction. Defects in RAR signaling have been implicated in cancer. TEL, a member of the ETS f
Externí odkaz:
https://doaj.org/article/901d374f685542e7955269b26b29e914
Autor:
Karel H. M. van Wely, Julio Gutiérrez, Ricardo Villares, Pablo Manrique, Yolanda R. Carrasco, Cristina Pacios-Bras, Astrid Alonso-Guerrero, Fernando Gutiérrez del Burgo, Carmen Mora Gallardo, Tirso Pons, Sara Roman-Garcia, Carlos Martínez-A
Publikováno v:
SSRN Electronic Journal.
Microtubule (MT) dynamics are central to eukaryotic cell organization, intracellular transport, division, adhesion, polarization, and migration. Unbalanced MT stability is associated with metastasis and neurodegenerative diseases. We show that altere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41118c2ad1d127d3fbba60599f7aff55
https://doi.org/10.2139/ssrn.3428482
https://doi.org/10.2139/ssrn.3428482
Autor:
Adam H. Tencer, Jovylyn Gatchalian, Yi Zhang, Tatiana G. Kutateladze, Brianna J. Klein, A. Ali Khan, Karel H. M. van Wely, Brian D. Strahl
The protein partner of Sans-fille (PPS) and its human homolog DIDO mediate diverse chromatin activities, including the regulation of stemness genes in embryonic stem cells and splicing in Drosophila. Here, we show that the PHD fingers of PPS and DIDO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0fa1cf7b68edc62ed30152dced1531
https://europepmc.org/articles/PMC5679713/
https://europepmc.org/articles/PMC5679713/
Autor:
Krzysztof Krajewski, Ruben D Rosas Ospina, Jovylyn Gatchalian, Brianna J. Klein, Andrea Mansilla Liendo, Tatiana G. Kutateladze, Carmen Mora Gallardo, Forest H. Andrews, Stephen A. Shinsky, Brian D. Strahl, Karel H. M. van Wely
Publikováno v:
Nucleic Acids Research
Histone post-translational modifications, and specific combinations they create, mediate a wide range of nuclear events. However, the mechanistic bases for recognition of these combinations have not been elucidated. Here, we characterize crosstalk be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703d445c170888f90458b2f7e4185c7b
Autor:
Gerard Grosveld, Arjan Buijs, Karel H. M. van Wely, Magda A. Meester-Smoor, Albert Jan Aarnoudse, Anita Hellemons, Ellen C. Zwarthoff, Pim den Besten, Anco C. Molijn
Publikováno v:
Oncogene. 22:699-709
The t(12;22) creates an MN1-TEL fusion gene leading to acute myeloid leukemia. The fusion partner TEL (ETV6) is a member of the ETS family of transcription factors. The nature of the other fusion partner, MN1, has not been investigated in detail unti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea79f068ee2a6f70b4c9e45982ab60e
https://doi.org/10.1038/sj.onc.1206124
https://doi.org/10.1038/sj.onc.1206124