Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Karel Boissinot"'
1
Akademický článek
Emergence of a mutation in the nucleocapsid gene of SARS-CoV-2 interferes with PCR detection in Canada
Autor: Sandra Isabel, Mariana Abdulnoor, Karel Boissinot, Marc R. Isabel, Richard de Borja, Philip C. Zuzarte, Calvin P. Sjaarda, Kevin R. Barker, Prameet M. Sheth, Larissa M. Matukas, Jonathan B. Gubbay, Alisson J. McGeer, Samira Mubareka, Jared T. Simpson, Ramzi Fattouh
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract The emergence of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) was met with rapid development of robust molecular-based detection assays. Many SARS-CoV-2 molecular tests target multiple genetic regions of the virus to maximize d
Externí odkaz: https://doaj.org/article/a6597e6f3e164ef8a2191d94f801c382
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4
Akademický článek
Correlation between microarray DNA hybridization efficiency and the position of short capture probe on the target nucleic acid
Autor: Régis Peytavi, Liu-ying Tang, Frédéric R. Raymond, Karel Boissinot, Luc Bissonnette, Maurice Boissinot, François J. Picard, Ann Huletsky, Marc Ouellette, Michel G. Bergeron
Publikováno v: BioTechniques, Vol 39, Iss 1, Pp 89-96 (2005)
The hybridization behavior of small oligonucleotides arrayed on glass slides is currently unpredictable. In order to examine the hybridization efficiency of capture probes along target nucleic acid, 20-mer oligonucleotide probes were designed to hybr
Externí odkaz: https://doaj.org/article/1e0eb08622054d648aa1d8a3fc543546
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7
A Novel Approach to Detect IDH Point Mutations in Gliomas Using Nanopore Sequencing, Test Validation for the Clinical Laboratory
Autor: Mashiat L, Mimosa, Wafa, Al-Ameri, Jared T, Simpson, Michael, Nakhla, Karel, Boissinot, David G, Munoz, Sunit, Das, Harriet, Feilotter, Ramzi, Fattouh, Rola M, Saleeb
Publikováno v: The Journal of molecular diagnostics : JMD.
The use of standard next generation sequencing (NGS) technologies to detect key mutations in isocitrate dehydrogenase (IDH) genes for glioma diagnosis imposes several challenges including high capital cost and turnaround delays associated with the ne
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4d7790f18e07741c67372f208a70b528
https://pubmed.ncbi.nlm.nih.gov/36565986
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8
Real-time monitoring of bead-based DNA hybridization in a microfluidic system: study of amplicon hybridization behavior on solid supports
Autor: Sébastien Chapdelaine, David Béliveau-Viel, Lidija Malic, Eric A. Martel, Denis Boudreau, Teodor Veres, Michel G. Bergeron, Matthias Geissler, Jean-François Gravel, Maurice Boissinot, Régis Peytavi, Karel Boissinot
Publikováno v: The Analyst. 146:4226-4234
DNA hybridization phenomena occurring on solid supports are not understood as clearly as aqueous phase hybridizations and mathematical models cannot predict some empirically obtained results. Ongoing research has identified important parameters but r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbd7273c9f2353845d85c912e8d4a367
https://doi.org/10.1039/d1an00394a
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10
Structured oligonucleotides for target indexing to allow single-vessel PCR amplification and solid support microarray hybridization
Autor: Karel Boissinot, Laurie D. Girard, Michel G. Bergeron, Maurice Boissinot, Régis Peytavi
Publikováno v: The Analyst. 140:912-921
The combination of molecular diagnostic technologies is increasingly used to overcome limitations on sensitivity, specificity or multiplexing capabilities, and provide efficient lab-on-chip devices. Two such techniques, PCR amplification and microarr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c39c80834ef762d6a47eb62b3999d3
https://doi.org/10.1039/c4an01352b
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