Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Karel A. Erion"'
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149008 (2016)
Lipid signals derived from lipolysis and membrane phospholipids play an important role in glucose-stimulated insulin secretion (GSIS), though the exact secondary signals remain unclear. Previous reports have documented a stimulatory role of exogenous
Externí odkaz:
https://doaj.org/article/97a75d51ca57423d887dad9366b20287
Autor:
Jill M. Norris, Andrew T. Hattersley, Mark I. McCarthy, Jose C. Florez, Stephen S. Rich, Louis H. Philipson, John J. Nolan, Wendy K. Chung, Marie-France Hivert, William T. Cefalu, Karel A. Erion, Allison T. McElvaine, Ewan R. Pearson, Christine G. Lee, Paul W. Franks
Publikováno v:
Diabetes Care
Diabetologia
Diabetologia
The convergence of advances in medical science, human biology, data science, and technology has enabled the generation of new insights into the phenotype known as “diabetes.” Increased knowledge of this condition has emerged from populations arou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ad2c984c28974d5f2f3386e0c9f9be
https://pubmed.ncbi.nlm.nih.gov/32561617
https://pubmed.ncbi.nlm.nih.gov/32561617
Autor:
S. Schwartz, James A. Hamilton, Karel A. Erion, G. Tasik, Nathan E. Burritt, Barbara E. Corkey, N. Huang, J. Bodde, Antonio M. Gotto, K. Sao, C. Sponseller, E. Gajrawala, Elizabeth Anne Kolar, M. Sitaram, David P. Hajjar, Jude T. Deeney
Publikováno v:
Atherosclerosis. 331:e170
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e920b9ad2584475370292393d957453
https://doi.org/10.1016/j.atherosclerosis.2021.06.518
https://doi.org/10.1016/j.atherosclerosis.2021.06.518
Autor:
Joshua J. Wilhelm, Jakob D. Wikstrom, Eleni Ritou, Melena D. Bellin, Orian S. Shirihai, Richard G. Kibbey, Zachary Swanson, Linsey Stiles, Siyouneh Baghdasarian, Karel A. Erion, Nour Alsabeeh, Jin Li, Samuel B. Sereda, Marc Liesa, Evan P. Taddeo, Muhamad Abdulla
Publikováno v:
Diabetes
Fasting hyperinsulinemia precedes the development of type 2 diabetes. However, it is unclear whether fasting insulin hypersecretion is a primary driver of insulin resistance or a consequence of the progressive increase in fasting glycemia induced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581d4a20e4236c1068611cfeedd4774f
https://pubmed.ncbi.nlm.nih.gov/31740442
https://pubmed.ncbi.nlm.nih.gov/31740442
Autor:
Aaron H. Colby, Karel A. Erion, Mark W. Grinstaff, Dovi Shlomo, Marc Liesa, Jialiu Zeng, Orian S. Shirihai, Kyle Trudeau, Guy Las, Essam A. Assali, Evan P. Taddeo
Publikováno v:
FASEB J
Chronic exposure of pancreatic β cells to high concentrations of free fatty acids leads to lipotoxicity (LT)‐mediated suppression of glucose‐stimulated insulin secretion. This effect is in part caused by a decline in mitochondrial function as we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ccf94261cdb5bbac13f59a3b9d381fd
https://pubmed.ncbi.nlm.nih.gov/30550357
https://pubmed.ncbi.nlm.nih.gov/30550357
Autor:
Barbara E. Corkey, Karel A. Erion
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
This review is motivated by the need to question dogma that has not yielded significant improvements in outcomes of Type 2 Diabetes treatment: that insulin resistance is the driver of ß-Cell failure and resulting hyperglycemia. We highlight the fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c9c766f93e5ee288f2c124a20cc660
https://doi.org/10.3389/fendo.2018.00532
https://doi.org/10.3389/fendo.2018.00532
Autor:
Karel A. Erion, Barbara E. Corkey
Publikováno v:
Current Obesity Reports
Purpose of Review This perspective is motivated by the need to question dogma that does not work: that the problem is insulin resistance (IR). We highlight the need to investigate potential environmental obesogens and toxins. Recent Findings The preq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd08ba007490d4e4d454f51325793de9
https://pubmed.ncbi.nlm.nih.gov/28466412
https://pubmed.ncbi.nlm.nih.gov/28466412
Autor:
James A. Hamilton, Antonio M. Gotto, C. Sponseller, Elizabeth Anne Kolar, G. Datu Tasik, D.P. Hajjar, Barbara E. Corkey, M. Sitaram, Karel A. Erion, Nathan E. Burritt, Jude T. Deeney, J. Bodde
Publikováno v:
Atherosclerosis. 287:e94
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::862fffb190e202987fcd9a466a6e810c
https://doi.org/10.1016/j.atherosclerosis.2019.06.272
https://doi.org/10.1016/j.atherosclerosis.2019.06.272
Publikováno v:
The Journal of biological chemistry. 290(26)
Hyperinsulinemia (HI) is elevated plasma insulin at basal glucose. Impaired glucose tolerance is associated with HI, although the exact cause and effect relationship remains poorly defined. We tested the hypothesis that HI can result from an intrinsi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59fa5208af72ab343551af3f7cc923e
https://pubmed.ncbi.nlm.nih.gov/25934392
https://pubmed.ncbi.nlm.nih.gov/25934392
Publikováno v:
The FASEB Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a634aee61180c518005ab4c9be9d8862
https://doi.org/10.1096/fasebj.27.1_supplement.1010.13
https://doi.org/10.1096/fasebj.27.1_supplement.1010.13