Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Karel Šindelář"'
Publikováno v:
Collection of Czechoslovak Chemical Communications. 60:894-902
Reactions of bisulfite addition compounds prepared in situ from cyclohexanone or 3,4,5,6-tetrahydro-2H-thiopyran-3-one with potassium cyanide and corresponding amines resulted with high yields in amino nitriles type of V and VI. These compounds were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55e71a092c545e23090d7d276ebf5b48
https://doi.org/10.1135/cccc19950894
https://doi.org/10.1135/cccc19950894
Publikováno v:
Collection of Czechoslovak Chemical Communications. 59:667-674
Alkylation of ethyl nipecotate with bromides VII - X gave amino esters Ib - Vb. Alkylation of ethyl piperazine-2-carboxylate with 4-bromo-1,1-diphenyl-1-butene afforded compound Vb. Final product Ia - Va were obtained by acid hydrolysis of correspond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88e7f17d4cdabba1fb3992283740a75c
https://doi.org/10.1135/cccc19940667
https://doi.org/10.1135/cccc19940667
Publikováno v:
Collection of Czechoslovak Chemical Communications. 57:194-203
(Arylthio)benzoic acids IIa - IIe and VIb - VId were transformed via the acid chlorides to the N,N-dimethylamides which were reduced either with diborane "in situ" or with lithium aluminium hydride to N,N-dimethyl-(arylthio)benzylamines Ia - Ie and V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::188bfd759287591cebaf7f22156bc4d3
https://doi.org/10.1135/cccc19920194
https://doi.org/10.1135/cccc19920194
Publikováno v:
Collection of Czechoslovak Chemical Communications. 56:2482-2493
Reaction of nitrile IVa with the Grignard’s reagent 1-methyl-4-piperidylmagnesium chloride gave carbinol XIb as product. Carbinols XIa and XIb were dehydrated and hydrolysed with dilute hydrochloric acid to give hydrochlorides of the tricyclic amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4031cdc98dddb60f0f955302aa8f4dd
https://doi.org/10.1135/cccc19912482
https://doi.org/10.1135/cccc19912482
Autor:
Zdeněk Polívka, Karel Šindelář, Karel Dobrovský, Jiřina Metyšová, Martin Valchář, Josef Pomykáček
Publikováno v:
Collection of Czechoslovak Chemical Communications. 56:449-458
3-(3-Methoxyphenylthio)thiophene-2-carboxylic acid (IV) and 2-(3-methoxyphenylthio)thiophene-3-carboxylic acid (VII) were transformed via acid chlorides and dimethylamides to the amines V and VIII which were demethylated to the phenolic amines VI and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15ec7fed97e982c8663b373afc8bdac1
https://doi.org/10.1135/cccc19910449
https://doi.org/10.1135/cccc19910449
Autor:
Jiřina Metyšová, Emil Svátek, Karel Šindelář, Jiří Holubek, Martin Valchář, Zdeněk Polívka, Josef Pomykáček, Karel Dobrovský
Publikováno v:
Collection of Czechoslovak Chemical Communications. 56:459-477
A series of potential metabolites of the potent inhibitor of 5-hydroxytryptamine re-uptake in the brain structures – moxifetin (I) – i.e. the O-methylated and hydroxylated, further methoxylated, and N-monodemethylated analogues (III – VII, IX,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d36b5b557bde7876d5e29abda96ba6b
https://doi.org/10.1135/cccc19910459
https://doi.org/10.1135/cccc19910459
Publikováno v:
Collection of Czechoslovak Chemical Communications. 55:1067-1076
Reaction of 2-(ethoxycarbonylamino)ethanol with 2-propylpentanoyl chloride gave the ester III. N-(4-Piperidinyl)-2-propylpentanamide (V) was prepared via the 1-benzyl-4-piperidinyl derivative IV and was acylated with ethanesulfonyl chloride and 2-pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::541e04c42496674fc0ae473dd01fab55
https://doi.org/10.1135/cccc19901067
https://doi.org/10.1135/cccc19901067
Autor:
Marie Vlková, Miroslav Ryska, Josef Pomykáček, Jiřina Metyšová, Jiří Jílek, Miroslav Protiva, Karel Šindelář, Jiří Holubek, Vladimír Valenta, M. Hrubantova, Emil Svátek
Publikováno v:
Collection of Czechoslovak Chemical Communications. 55:2282-2303
The isofloxythepin (I) metabolite IV was synthesized via the acids IX and XI and the esters X and XII. The enamine VIII was prepared from 3-fluoro-8-(2-propyl)dibenzo[b,f]thiepin-10(11H)-one by two methods and was reduced to I. Cloflumide (II) was ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecc347396971913909c26a58fb018f57
https://doi.org/10.1135/cccc19902282
https://doi.org/10.1135/cccc19902282
Autor:
Karel Šindelář, Miroslav Protiva, Ivan Krejci, Vladimír Valenta, Antonín Dlabač, Miroslav Ryska, Jiří Holubek
Publikováno v:
Collection of Czechoslovak Chemical Communications. 55:1613-1629
The title compounds VI-XXIII were prepared by heating ethyl (2-oxo-1-pyrrolidinyl)acetate (II) with a series of N-monosubstituted piperazines. The propionamides XXVI and XXX were obtained by reactions of the acid chlorides IV and XXXIII with 3-(1-pip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb2141c44cdd40bc28fa16bfb82286cb
https://doi.org/10.1135/cccc19901613
https://doi.org/10.1135/cccc19901613
Autor:
Miroslav Ryska, Jiří Urban, Zdeněk Šedivý, Martin Valchář, Jiřina Metyšová, Zdeněk Polívka, Miroslav Protiva, Josef Pomykáček, Antonín Dlabač, Jiří Holubek, Karel Šindelář, Emil Svátek, Ivan Koruna, M. Hrubantova
Publikováno v:
Collection of Czechoslovak Chemical Communications. 55:1077-1098
2-(Methoxyphenylthio)benzaldehydes Xa-Xd were reacted with nitroethane in boiling acetic acid to give the corresponding 1-aryl-2-nitropropenes XIIa-XIId; benzonitriles XIIIa and XIIIc and benzaldoximes XXIc and XXId were isolated as by-products. Chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82ee12965166bc263081a10e331693f9
https://doi.org/10.1135/cccc19901077
https://doi.org/10.1135/cccc19901077