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COBALT: A Confirmatory Trial of Obeticholic Acid in Primary Biliary Cholangitis With Placebo and External Controls.

Autor: Kowdley KV; Liver Institute Northwest and Elson S. Floyd College of Medicine, Washington State University, Seattle, Washington, USA., Hirschfield GM; Toronto Centre for Liver Disease, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada., Coombs C; Real World Evidence, Syneos Health, Morrisville, North Carolina, USA., Malecha ES; Intercept Pharmaceuticals, Morristown, New Jersey, USA., Bessonova L; Intercept Pharmaceuticals, Morristown, New Jersey, USA., Li J; Intercept Pharmaceuticals, Morristown, New Jersey, USA., Rathnayaka N; Department of Population Health Sciences, Duke University, Durham, North Carolina, USA., Mells G; Cambridge University Hospitals NHS Foundation Trust MRC Clinical Academic Research Partner, Academic Department of Medical Genetics, University of Cambridge, Cambridge, UK., Jones DE; Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK., Trivedi PJ; National Institute for Health and Care Research (NIHR) Birmingham Biomedical Research Centre, Centre for Liver and Gastrointestinal Research, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Hansen BE; Department of Epidemiology and Biostatistics, Erasmus MC, Rotterdam, Netherlands.; IHPME University of Toronto, Toronto, Ontario, Canada.; Toronto Centre for Liver Disease and TGHRI, University Health Network, Toronto, Ontario, Canada., Smith R; Cambridge Liver Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Wason J; Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK., Hiu S; Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK., Kareithi DN; Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, UK., Mason AL; Division of Gastroenterology, University of Alberta, Edmonton, Alberta, Canada., Bowlus CL; University of California Davis, Sacramento, California, USA., Muller K; Flinders Medical Centre, Adelaide, South Australia, Australia., Carbone M; University of Milano-Bicocca, Milano, Italy., Berenguer M; La Fe University Hospital, IISLaFe, Ciberehd, University of Valencia, Valencia, Spain., Milkiewicz P; Medical University of Warsaw, Warszawa, Poland.; Translational Medicine Group, Pomeranian Medical University, Szczecin, Poland., Adekunle F; Intercept Pharmaceuticals, London, UK., Villamil A; Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

Publikováno v: The American journal of gastroenterology [Am J Gastroenterol] 2024 Aug 14. Date of Electronic Publication: 2024 Aug 14.