Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kareen Riviere"'
Publikováno v:
Journal of Controlled Release. 153:288-296
To test the hypothesis that co-delivery of synergistic drug combinations in the same liposome provides a better anti-tumor effect than the drugs administered in separate liposomes, fluoroorotic acid (FOA) alone and in combination with irinotecan (IRN
Autor:
Kareen Riviere, Francis C. Szoka, Virginia Platt, Limin Cao, Zhaohua Huang, Matthew R. Tiffany
Publikováno v:
Bioconjugate Chemistry. 21:892-902
Metal chelation-ligand interactions, such as occur between nitrilotriacetic acid (NTA)-nickel and multihistidines, enable the noncovalent attachment of histidine-modified proteins to liposomes and other particles. We compared three lipids: a mono-NTA
Publikováno v:
Pharmaceutical research. 28(5)
To investigate how likely two extended release formulations are to be bioequivalent when they demonstrate f2 similarity. Dissolution profiles were simulated using the Weibull model and varying model parameters around those of a reference profile. The
Publikováno v:
Journal of drug targeting. 19(1)
The effect of folate-targeted liposomal doxorubicin (FTL-Dox) has been well characterized in folate receptor (FR) over-expressing tumors in vitro, particularly in KB human carcinoma cells. However, there are few studies evaluating the in vivo efficac
Publikováno v:
Bioconjugate chemistry. 17(5)
An efficient method to synthesize hyaluronan oligosaccharide lipid conjugates is described. This strategy is based on the introduction of a double bond in the glucuronic acid of the hyaluronic acid (HA), by the biodegradation of HA with hyaluronate l
Publikováno v:
Virology. 349(1)
Murine fibroblasts expressing viral receptors and human cyclin T1 allow HIV-1 entry and viral gene expression but do not support efficient assembly. A chimeric HIV-1 carrying a non-homologous matrix (MA) from murine leukemia virus in place of HIV-1 M
Publikováno v:
Bioconjugate Chemistry; May2010, Vol. 21 Issue 5, p892-902, 11p