Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kareen L.K. Coulombe"'
Autor:
Kiera D. Dwyer, Kareen L.K. Coulombe
Publikováno v:
Bioactive Materials, Vol 6, Iss 7, Pp 2198-2220 (2021)
The mechanical environment and anisotropic structure of the heart modulate cardiac function at the cellular, tissue and organ levels. During myocardial infarction (MI) and subsequent healing, however, this landscape changes significantly. In order to
Externí odkaz:
https://doaj.org/article/aae55b4a5e1f4f6799968e5046545a29
Publikováno v:
Biomarker Insights, Vol 2015, Iss Suppl. 1, Pp 1-9 (2015)
Externí odkaz:
https://doaj.org/article/7ae5a350c9c5449fa4e26f0c78b9ac16
Autor:
Kareen L.K. Coulombe, Kiera D. Dwyer
Publikováno v:
Bioactive Materials, Vol 6, Iss 7, Pp 2198-2220 (2021)
Bioactive Materials
Bioactive Materials
The mechanical environment and anisotropic structure of the heart modulate cardiac function at the cellular, tissue and organ levels. During myocardial infarction (MI) and subsequent healing, however, this landscape changes significantly. In order to
Publikováno v:
Tissue Eng Part A
With this work, we design alginate-based hydrogels for therapeutically directing revascularization and repair processes in vivo. We immobilize pleiotrophin (PTN) in injectable hydrogel formulations as the target factor to stimulate proangiogenic resp
Publikováno v:
Journal of Biomedical Materials Research Part A. 109:1726-1736
A formidable challenge in regenerative medicine is the development of stable microvascular networks to restore adequate blood flow or to sustain graft viability and long-term function in implanted or ischemic tissues. In this work, we develop a biomi
Publikováno v:
Tissue Engineering. Part C, Methods
A great variety of natural and synthetic polymer materials have been utilized in soft tissue engineering as extracellular matrix (ECM) materials. Natural polymers, such as collagen and fibrin hydrogels, have experienced especially broad adoption due
Autor:
Bum-Rak Choi, Kareen L.K. Coulombe, Arvin H Soepriatna, Tae Yun Kim, Mark C Daley, Elena Song
Publikováno v:
Cell Mol Bioeng
INTRODUCTION: Although atrial fibrillation is the most prevalent disorder of electrical conduction, the mechanisms behind atrial arrhythmias remain elusive. To address this challenge, we developed a robust in vitro model of 3D atrial microtissue from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a410ed88cc1add7c7bfc288f7dc8d8e
https://europepmc.org/articles/PMC8548481/
https://europepmc.org/articles/PMC8548481/
Autor:
Kiera D. Dwyer, Phillip R Schmitt, Kareen L.K. Coulombe, Arvin H Soepriatna, James Reid, Anthony Callanan
Publikováno v:
Biofabrication
Mimicking the native three-dimensional microenvironment is of crucial importance when biofabricating a new healthcare material. One aspect of the native tissue that is often omitted when designing a suitable scaffold is its anisotropy. Not only is ma
Autor:
Tae Yun Kim, Ulrike Mende, Fabiola Munarin, Rajeev J. Kant, Bum-Rak Choi, Kareen L.K. Coulombe, Arvin H Soepriatna, Celinda M. Kofron
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Cardiotoxicity of pharmaceutical drugs, industrial chemicals, and environmental toxicants can be severe, even life threatening, which necessitates a thorough evaluation of the human response to chemical compounds. Predicting risks for arrhythmia and
Publikováno v:
J Mech Behav Biomed Mater
Cardiac patch therapies promise to restore heart function and lower the risk of heart failure after heart attack. Fiber–matrix engineered tissue scaffolds have gained significant attention due to their tunable micro-structures, providing nonlinear