Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Kareem Ebeid"'
Autor:
Hamada H. H. Mohammed, Amer Ali Abd El-Hafeez, Kareem Ebeid, Aml I. Mekkawy, Mohammed A. S. Abourehab, Emad I. Wafa, Suhaila O. Alhaj-Suliman, Aliasger K. Salem, Pradipta Ghosh, Gamal El-Din A. Abuo-Rahma, Alaa M. Hayallah, Samar H. Abbas
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1346-1363 (2022)
A series of novel 1,2,3-triazole-linked ciprofloxacin-chalcones 4a-j were synthesised as potential anticancer agents. Hybrids 4a-j exhibited remarkable anti-proliferative activity against colon cancer cells. Compounds 4a-j displayed IC50s ranged from
Externí odkaz:
https://doaj.org/article/606a96ca25cb42d88708edc3b4fecfee
Autor:
Shakoora A. Sabree, Caitlin D. Lemke-Miltner, Sue E. Blackwell, Chaobo Yin, Aaron Bossler, Kareem Ebeid, Aliasger K. Salem, George J. Weiner
Publikováno v:
Vaccines, Vol 9, Iss 9, p 982 (2021)
Vidutolimod, also known as CMP-001, is a virus-like particle composed of the Qβ bacteriophage coat protein encasing a TLR9 agonist. Vidutolimod injected intratumorally is showing promise in early phase clinical trials based on its ability to alter t
Externí odkaz:
https://doaj.org/article/166b965f36da434991cb4fa3e3371783
Autor:
Lucas Amaral-Machado, Wógenes N. Oliveira, Éverton N. Alencar, Ana Katarina M. Cruz, Hugo Alexandre O. Rocha, Kareem Ebeid, Aliasger K. Salem, Eryvaldo Sócrates T. Egito
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 117, Iss , Pp - (2019)
Bullfrog oil, an animal oil extracted from the adipose tissue of Rana catesbeiana Shaw, showed promising cytotoxic activity against melanoma cells and, therefore, has the potential to become a pharmaceutical active compound. However, there is a lack
Externí odkaz:
https://doaj.org/article/cd5af7bafa704840a35bd1f45865212c
Autor:
Rasheid Smith, Emad I. Wafa, Sean M. Geary, Kareem Ebeid, Suhaila O. Alhaj-Suliman, Aliasger K. Salem
Publikováno v:
Science Advances. 8
In clinical settings, cancer vaccines as monotherapies have displayed limited success compared to other cancer immunotherapeutic treatments. Nanoscale formulations have the ability to increase the efficacy of cancer vaccines by combatting the immunos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b86f1e95ba498fc7f76d68fea925b54
https://doi.org/10.1126/sciadv.abk3150
https://doi.org/10.1126/sciadv.abk3150
Autor:
Suhaila O. Alhaj-Suliman, Youssef W. Naguib, Emad I. Wafa, Sanjib Saha, Kareem Ebeid, Xiangbing Meng, Hamada H. Mohammed, Gamal El-Din A. Abuo-Rahma, Shujie Yang, Aliasger K. Salem
Publikováno v:
Biomaterials. 296:122093
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c337e7d36b5ae4e8731430c7117959b9
https://doi.org/10.1016/j.biomaterials.2023.122093
https://doi.org/10.1016/j.biomaterials.2023.122093
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071621271
Methods in Molecular Biology ISBN: 9781071621271
Nonalcoholic steatohepatitis (NASH) is an aggressive liver disease that is considered a major cause of liver cirrhosis and hepatocellular carcinoma. NASH is characterized by multiple underlying genetic mutations, with no approved cure to date. Gene t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f43a7eab887c0adb59fb6b85339c9d
https://pubmed.ncbi.nlm.nih.gov/35213004
https://pubmed.ncbi.nlm.nih.gov/35213004
Autor:
Kanawat Wiwatchaitawee, Kareem Ebeid, Juliana C. Quarterman, Youssef Naguib, MD Yousuf Ali, Claudia Oliva, Corinne Griguer, Aliasger K. Salem
Publikováno v:
Bioconjug Chem
Glioblastoma multiforme (GBM) is the most malignant type of brain tumor and has an extremely poor prognosis. Current treatment protocols lack favorable outcomes, and alternative treatments with superior efficacy are needed. In this study, we demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f08de8c7925d64a54646a5ab0c614d
https://europepmc.org/articles/PMC9662320/
https://europepmc.org/articles/PMC9662320/
Autor:
Kareem Ebeid, Juliana C. Quarterman, Aliasger K. Salem, Youssef W. Naguib, Sean M. Geary, Aml I Mekkawy, Kanawat Wiwatchaitawee
Publikováno v:
Drug Deliv Transl Res
Endometrial cancer (EC) is the most common gynecological cancer that affects the female reproductive organs. The standard therapy for EC for at least the past two decades has been chemotherapy and/or radiotherapy. PD98059 is a reversible MEK inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5668cfdad7369f87499e895bd8bbf083
https://europepmc.org/articles/PMC8995400/
https://europepmc.org/articles/PMC8995400/
Publikováno v:
The American Journal of Case Reports
Patient: Male, 41 Final Diagnosis: Mitral valve endocarditis Symptoms: ltered mental status • fatigue • fever • myalgia Medication: — Clinical Procedure: — Specialty: Cardiology Objective: Unusual clinical course Background: Immediate evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32ea04a3cf242a5f58402c75af024c93
https://doi.org/10.12659/ajcr.918592
https://doi.org/10.12659/ajcr.918592
Autor:
Aml I, Mekkawy, Youssef W, Naguib, Suhaila O, Alhaj-Suliman, Emad I, Wafa, Kareem, Ebeid, Timothy, Acri, Aliasger K, Salem
Publikováno v:
Int J Pharm
Melanoma, the most malignant form of skin cancer, shows resistance to traditional anticancer drugs including paclitaxel (PTX). Furthermore, over 50% of melanoma cases express the BRAF(V600E) mutation which activates the MAPK pathway increasing cell p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c6204eaa755749e2562e759b4e9c1d2
https://pubmed.ncbi.nlm.nih.gov/34252520
https://pubmed.ncbi.nlm.nih.gov/34252520