Non-clinical acute and chronic toxicity evaluations of Cissus sicyoides L. (Vitaceae) hydroalcoholic leaf extract

Autor: Margareth de Fátima Formiga Melo Diniz, Hilzeth de Luna Freire Pessôa, Camila Bomfim de Sá, Andressa Brito Lira, Luciana da Silva Nunes Ramalho, Kardilandia Mendes de Oliveira, Gabriela Tafaela Dias, Cinthia Rodrigues Melo, Josué do Amaral Ramalho, Caliandra Maria Bezerra Luna Lima

Publikováno v: Toxicology Reports, Vol 5, Iss , Pp 890-896 (2018)

Cissus sicyoides (Cs) has been traditionally used to treat diabetes and belongs to the family Vitaceae, and is known as “vegetable insulin''. This study aimed to evaluate the acute and chronic non-clinical toxicity of hydroalcoholic extract from th

Externí odkaz: https://doaj.org/article/91db007699344c8abedd8b87993655a6

Avaliação do efeito antidepressivo símile in vivo de um derivado de chalcona e sua modelagem molecular por docking

Autor: Flávio Valadares Pereira Borges, Humberto Hugo Nunes de Andrade, Abrahão Alves de Oliveira Filho, Álefe Brito Monteiro, Luis Cezar Rodrigues, Gabrielly Diniz Duarte, Liana Clébia de Morais Pordeus, Caliandra Maria Bezerra Luna Lima, Cinthia Rodrigues Melo, Kardilandia Mendes de Oliveira

Publikováno v: Revista Eletrônica Acervo Saúde. 13:e5573

Objetivo: Investigar a substância GA-4, quanto a ser um potente candidato a antidepressivo, além de identificar seu possível mecanismo de ação através de docking. Métodos: Foram realizados ensaios psicofarmacológicos in vivo, devidamente auto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8894cec3b37093e2d359e050cd03a14
https://doi.org/10.25248/reas.e5573.2021

Non-clinical acute and chronic toxicity evaluations of

Autor: Margareth, de Fátima Formiga Melo Diniz, Hilzeth, de Luna Freire Pessôa, Camila Bomfim, de Sá, Andressa Brito, Lira, Luciana, da Silva Nunes Ramalho, Kardilandia Mendes, de Oliveira, Gabriela Tafaela, Dias, Cinthia Rodrigues, Melo, Josué, do Amaral Ramalho, Caliandra Maria, Bezerra Luna Lima

Publikováno v: Toxicology Reports

Graphical abstract
Highlights • The Cissus sicyoides species has several pharmacological activities. • The ethanolic extract from the leaves of Cissus caused few blood changes at the 40.5 mg/kg dose in the acute study. • In the chronic stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f7f8e23e3c672deabb72dfd3cde9ee59
https://pubmed.ncbi.nlm.nih.gov/30181957

Clinical safety evaluation of a tea containing Cissampelos sympodialis in healthy volunteers

Autor: Aretuza Iolanda Pimentel de Almeida Torres, Margareth de Fátima Formiga Melo Diniz, Andressa Brito Lira, Cícero Flávio Soares Aragão, Josué do Amaral Ramalho, Caliandra Maria Bezerra Luna Lima, Luciana da Silva Nunes Ramalho, Liane Franco Barros Mangueira, Kardilandia Mendes de Oliveira, Valério Marcelo Vasconcelos do Nascimento

Publikováno v: Revista Brasileira de Farmacognosia, Vol 25, Iss 5, Pp 491-498
Revista Brasileira de Farmacognosia, Volume: 25, Issue: 5, Pages: 491-498, Published: OCT 2015
Revista Brasileira de Farmacognosia, Vol 25, Iss 5, Pp 491-498 (2015)
Revista Brasileira de Farmacognosia v.25 n.5 2015
Revista Brasileira de Farmacognosia
Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA

Cissampelos sympodialis Eichler, Menispermaceae, is widely used by Indian tribes and folk medicine to treat various inflammatory disorders, including asthma. Clinical toxicological trials were made with the tea of C. sympodialis, a medicinal plant. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017b2490b9030bab2648b0e3442663b3
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000500491&lng=en&tlng=en