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Autor:
Karatkevich, Darya1,2,3 (AUTHOR), Deng, Haibin1,2 (AUTHOR), Gao, Yanyun1,2 (AUTHOR), Flint, Emilio1,2 (AUTHOR), Peng, Ren-Wang1,2 (AUTHOR), Schmid, Ralph Alexander1,2 (AUTHOR), Dorn, Patrick1,2 (AUTHOR) patrick.dorn@insel.ch, Marti, Thomas Michael1,2 (AUTHOR) patrick.dorn@insel.ch
Publikováno v:
International Journal of Molecular Sciences. Oct2022, Vol. 23 Issue 19, p11949. 13p.
Autor:
Deng, Haibin, Gao, Yanyun, Trappetti, Verdiana, Hertig, Damian, Karatkevich, Darya, Losmanová, Tereza, Urzì, Christian, Ge, Huixiang, Geest, Gerrit Adriaan, Bruggmann, Remy, Djonov, Valentin, Nuoffer, Jean-Marc, Vermathen, Peter, Zamboni, Nicola, Riether, Carsten, Ochsenbein, Adrian, Peng, Ren-Wang, Kocher, Gregor Jan, Schmid, Ralph, Dorn, Patrick, Marti, Thomas
Publikováno v:
Deng, Haibin; Gao, Yanyun; Trappetti, Verdiana; Hertig, Damian; Karatkevich, Darya; Losmanová, Tereza; Urzì, Christian; Ge, Huixiang; Geest, Gerrit Adriaan; Bruggmann, Remy; Djonov, Valentin; Nuoffer, Jean-Marc; Vermathen, Peter; Zamboni, Nicola; Riether, Carsten; Ochsenbein, Adrian; Peng, Ren-Wang; Kocher, Gregor Jan; Schmid, Ralph; Dorn, Patrick; ... (2022). Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage. Cellular and molecular life sciences, 79(8), p. 445. SP Birkhäuser Verlag Basel 10.1007/s00018-022-04453-5
Cellular and Molecular Life Sciences, 79 (8)
Cellular and Molecular Life Sciences, 79 (8)
Once considered a waste product of anaerobic cellular metabolism, lactate has been identified as a critical regulator of tumorigenesis, maintenance, and progression. The putative primary function of lactate dehydrogenase B (LDHB) is to catalyze the c
Autor:
Darya Karatkevich, Haibin Deng, Yanyun Gao, Emilio Flint, Ren-Wang Peng, Ralph Alexander Schmid, Patrick Dorn, Thomas Michael Marti
Publikováno v:
Karatkevich, Darya; Deng, Haibin; Gao, Yanyun; Flint, Emilio; Peng, Ren-Wang; Schmid, Ralph Alexander; Dorn, Patrick; Marti, Thomas Michael (2022). Schedule-Dependent Treatment Increases Chemotherapy Efficacy in Malignant Pleural Mesothelioma. International journal of molecular sciences, 23(19) MDPI 10.3390/ijms231911949
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11949
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11949
Malignant pleural mesothelioma (MPM) is a rare but aggressive thoracic malignancy with limited treatment options. One of the standard treatments for MPM is chemotherapy, which consists of concurrent treatment with pemetrexed and cisplatin. Pemetrexed