The evolution of lung cancer and impact of subclonal selection in TRACERx

Autor: Frankell, A.M., Dietzen, M., Al Bakir, M., Lim, E.L., Karasaki, T., Ward, S., Veeriah, S., Colliver, E., Huebner, A., Bunkum, A., Hill, M.S., Grigoriadis, K., Moore, D.A., Black, J.R.M., Liu, W.K., Thol, K., Pich, O., Watkins, T.B.K., Naceur-Lombardelli, C., Cook, D.E., Salgado, R., Wilson, G.A., Bailey, C., Angelova, M., Bentham, R., Martínez-Ruiz, C., Abbosh, C., Nicholson, A.G., Le Quesne, J., Biswas, D., Rosenthal, R., Puttick, C., Hessey, S., Lee, C., Prymas, P., Toncheva, A., Smith, J., Xing, W., Nicod, J., Price, G., Kerr, K.M., Naidu, B., Middleton, G., Blyth, K.G., Fennell, D.A., Forster, M.D., Lee, S.M., Falzon, M., Hewish, M., Shackcloth, M.J., Lim, E., Benafif, S., Russell, P., Boleti, E., Krebs, M.G., Lester, J.F., Papadatos-Pastos, D., Ahmad, T., Thakrar, R.M., Lawrence, D., Navani, N., Janes, S.M., Dive, C., Blackhall, F.H, Summers, Y., Cave, J., Marafioti, T., Herrero, J., Quezada, S.A., Peggs, K.S., Schwarz, R.F., Van Loo, P., Miedema, D.M., Birkbak, N.J., Hiley, C.T., Hackshaw, A., Zaccaria, S., Jamal-Hanjani, M., McGranahan, N., Swanton, C.

Lung cancer is the leading cause of cancer-associated mortality worldwide. Here we analysed 1,644 tumour regions sampled at surgery or during follow-up from the first 421 patients with non-small cell lung cancer prospectively enrolled into the TRACER

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=mdc______med::ef45f584564f3d0f221808d502071a8b
http://edoc.mdc-berlin.de/23266/5/23266suppl.zip

OA15.03 Clinicogenomic Landscape of Lymph Node Metastases in TRACERx

Autor: Karasaki, T., Al Bakir, M., Huebner, A., Black, J.R.M., Abbosh, C., McGranahan, N., Frankell, A.M., Jamal-Hanjani, M., Swanton, C.

Publikováno v: In Journal of Thoracic Oncology October 2024 19(10) Supplement:S43-S43

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A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer

Autor: Wu, Y., Biswas, D., Usaite, I., Angelova, M., Boeing, S., Karasaki, T., Veeriah, S., Czyzewska-Khan, J., Morton, C., Joseph, M., Hessey, S., Reading, J., Georgiou, A., Al-Bakir, M., McGranahan, N., Jamal-Hanjani, M., Hackshaw, A., Quezada, S.A., Hayday, A.C., Swanton, C.

Murine tissues harbor signature γδ T cell compartments with profound yet differential impacts on carcinogenesis. Conversely, human tissue-resident γδ cells are less well defined. In the present study, we show that human lung tissues harbor a resi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=mdc______med::e6f187944f063f251c4ee4f9be78f675
http://edoc.mdc-berlin.de/23128/1/23128oa.pdf

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