Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Karanvir Saini"'
Publikováno v:
Matrix biology : journal of the International Society for Matrix Biology. 111
Fibrillar proteins are principal components of extracellular matrix (ECM) that confer mechanical properties to tissues. Fibrosis can result from wound repair in nearly every tissue in adults, and it associates with increased ECM density and crosslink
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f1b221b27c248ee85d50dd43dd0eee
https://pubmed.ncbi.nlm.nih.gov/35764212
https://pubmed.ncbi.nlm.nih.gov/35764212
Tension-suppressed degradation of collagen controls tissue stiffness scaling with fibrillar collagen
Autor:
Karanvir Saini, Sangkyun Cho, Manu Tewari, Abdelaziz Jalil, Mai Wang, Manasvita Vashisth, Alex Kasznel, Kazuhiro Yamamoto, David M. Chenoweth, Dennis E. Discher
Publikováno v:
Biophysical Journal. 122:87a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08e534e0478311f6312df1f7bbbc5b45
https://doi.org/10.1016/j.bpj.2022.11.670
https://doi.org/10.1016/j.bpj.2022.11.670
Autor:
Karanvir Saini, Dennis E. Discher
Publikováno v:
Biochemistry. 58:4893-4902
Many proteins in cells and in the extracellular matrix assemble into force-bearing networks, and some proteins clearly transduce mechanical stimuli into biochemical signals. Although structural mechanisms remain poorly understood, the designs of such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88d276379adc418a886f502a6aad41dc
https://doi.org/10.1021/acs.biochem.9b00839
https://doi.org/10.1021/acs.biochem.9b00839
Publikováno v:
J Mech Behav Biomed Mater
Bone derives its mechanical strength from the complex arrangement of collagen fibrils (type-I primarily) reinforced with hydroxy-apatite (HAp) mineral crystals in extra- and intra-fibrillar compartments. This study demonstrates a novel approach to ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5cfb7ad47c832a83e7a687c13a478b2
https://doi.org/10.1016/j.jmbbm.2018.12.031
https://doi.org/10.1016/j.jmbbm.2018.12.031
Autor:
Kasznel A, AbdelAziz Jalil, Sangkyun Cho, Jason C. Andrechak, Kazuhiro Yamamoto, Manasvita Vashisth, Lawrence J. Dooling, Jerome Irianto, Cory Alvey, Karanvir Saini, Dennis E. Discher, David M. Chenoweth, Tiwari M
Collagen, the most abundant protein in mammals, contributes to the physical properties of different tissues during development, homeostasis, and disease. The adaptation of physical properties of tissues to mechanical stimuli is thus dependent on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd1663935031425fdd6790722b41e8e7
https://doi.org/10.1101/2021.02.07.430141
https://doi.org/10.1101/2021.02.07.430141
Autor:
Karanvir Saini, Manu Tewari, Sangkyun Cho, Manasvita Vashisth, Abdelaziz Jalil, Jason C. Andrechak, Alex Kasznel, David Chenoweth, Kazuhiro Yamamoto, Dennis E. Discher
Publikováno v:
Biophysical Journal. 121:492a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ca0bdb6455d5c234b83e6e99cefb85a
https://doi.org/10.1016/j.bpj.2021.11.318
https://doi.org/10.1016/j.bpj.2021.11.318
Publikováno v:
Matrix Biol
Tissue homeostasis depends on a balance of synthesis and degradation of constituent proteins, with turnover of a given protein potentially regulated by its use. Extracellular matrix (ECM) is predominantly composed of fibrillar collagens that exhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657ce29c41f2d79a118cdc0578d97678
https://pubmed.ncbi.nlm.nih.gov/31201857
https://pubmed.ncbi.nlm.nih.gov/31201857
Autor:
Sangkyun Cho, Lawrence J. Dooling, David M. Chenoweth, Manu Tewari, Kazuhiro Yamamoto, Alex Kasznel, Karanvir Saini, Manasvita Vashisth, Charlotte R. Pfeifer, Dennis E. Discher, Jason C. Andrechak, AbdelAziz Jalil, Cory Alvey, Jerome Irianto
Publikováno v:
Biophysical Journal. 118:398a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de149bb9b8e5387fa6eb57823a4767f
https://doi.org/10.1016/j.bpj.2019.11.2261
https://doi.org/10.1016/j.bpj.2019.11.2261
Autor:
Swati Sharma, Liqun Ning, Xiongbiao Chen, Karanvir Saini, Apoorv Rathi, N. K. Sharma, Abhinav Kumar, M. D. Sarker, Saman Naghieh
Publikováno v:
Journal of biomechanical engineering. 142(9)
Bone being a hierarchical composite material has a structure varying from macro- to nanoscale. The arrangement of the components of bone material and the bonding between fibers and matrix gives rise to its unique material properties. In this study, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199735055072412bfc536e7a863b3cb1
https://pubmed.ncbi.nlm.nih.gov/32191275
https://pubmed.ncbi.nlm.nih.gov/32191275
Autor:
Philip S. Brown, Thomas J. Wood, E. L. Talbot, Navin Kumar, Karanvir Saini, Jun Jie Wu, Jas Pal Singh Badyal, M.J. Egan, Colin D. Bain
Publikováno v:
Colloids and surfaces A : physiochemical and engineering aspects, 2015, Vol.481, pp.215-221 [Peer Reviewed Journal]
The oscillatory dynamics of picolitre water droplets following impact onto a range of hydrophobic surfaces is found to be influenced by the underlayer stiffness and thickness. The relative contributions of surface functionality versus subsurface hard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9a47fc773e2f696810d8bf409aca71d
https://doi.org/10.1016/j.colsurfa.2015.04.047
https://doi.org/10.1016/j.colsurfa.2015.04.047