Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Karan Singh Saini"'
Autor:
DIGAMBER, S S JAKHAR, KULDEEP SINGH, RAHUL KUMAR, GAGANDEEP SINGH, SULTAN SINGH, KARAN SINGH SAINI, VIKASH KUMAR
Publikováno v:
The Indian Journal of Agricultural Sciences, Vol 94, Iss 6 (2024)
Oxidative enzyme activity in plants is affected by innumerable direct as well as indirect ways. Sowing dates, nutrients in the form of foliar sprays and pre-seed treatments are the most common paths that can enhance the activity of oxidative enzymes
Externí odkaz:
https://doaj.org/article/770b77f986834f62829ce18a827b11d8
Autor:
Singh Pooja, Amirtharaj Francis, Singh Rajender, Rakesh Tamang, Raja Rajkumar, Karan Singh Saini, Kaling Megu, Madhu Mati Goel, Daminani Surekha, Digumarthi Raghunatha Rao, Lakshmi Rao, Lingadakai Ramachandra, Sandeep Kumar, Surender Kumar, Satti Vishnupriya, Kapaettu Satyamoorthy, Mahendra Pal Singh Negi, Kumarasamy Thangaraj, Rituraj Konwar
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75979 (2013)
IntroductionTGF-β1 is a multi-functional cytokine that plays an important role in breast carcinogenesis. Critical role of TGF-β1 signaling in breast cancer progression is well documented. Some TGF-β1 polymorphisms influence its expression; however
Externí odkaz:
https://doaj.org/article/d707e1b1ff1c4e0b81d28e78d36290f6
Autor:
Ruchi Saxena, Vishal Chandra, Murli Manohar, Kanchan Hajela, Utsab Debnath, Yenamandra S Prabhakar, Karan Singh Saini, Rituraj Konwar, Sandeep Kumar, Kaling Megu, Bal Gangadhar Roy, Anila Dwivedi
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66246 (2013)
Inhibition of epidermal growth factor receptor (EGFR) signaling is considered to be a promising treatment strategy for estrogen receptor (ER)-negative breast tumors. We have investigated here the anti-breast cancer properties of a novel anti-prolifer
Externí odkaz:
https://doaj.org/article/6857c3de7aa34bcc9c0118c41f4072ec
Publikováno v:
Breast Cancer: Current Trends in Molecular Research ISBN: 9781681089522
Cancer is the consequence of the recalcitrant multiplication of the transformed cells. Cancer cells grow and proliferate at a fast pace and do not follow normal regulation of cell division. Breast cancer is a heterogeneous group of diseases, which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c5bb4213149a064a6591a9db785dd5a
https://doi.org/10.2174/9781681089522112010005
https://doi.org/10.2174/9781681089522112010005
Autor:
Subhasis Das, Zhengjia Chen, Karan Singh Saini, Ajay Rana, Rong Ke, Basabi Rana, Navin Viswakarma, Kanchan Vishnoi, Rakesh Sathish Nair
Publikováno v:
Molecular Pharmacology. 99:1-16
Aberrant activation of Wnt/β-catenin axis occurs in several gastrointestinal malignancies due to inactivating mutations of adenomatous polyposis coli (in colorectal cancer) or activating mutations of β-catenin itself [in hepatocellular carcinoma (H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66b933e1dddf2808bb6fb8da981e7200
https://doi.org/10.1124/molpharm.120.000029
https://doi.org/10.1124/molpharm.120.000029
Autor:
Ramanpreet Shah, Jatinder Singh, Dhandeep Singh, Karan Singh Saini, Jaspreet Kaur, Dimple Sethi Chopra, Ram Sarup Singh, Amteshwar Singh Jaggi, Nirmal Singh
Publikováno v:
Medicinal Chemistry Research. 29:1400-1412
The role of mast cells can be protective or harmful; depending upon the physiological/pathological condition in which they get activated. The latter role is due to mast cell degranulation and release of an array of incendiary mediators. Mast cells ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b06a41218b223e3ed1e3c9b5c823b48
https://doi.org/10.1007/s00044-020-02555-y
https://doi.org/10.1007/s00044-020-02555-y
Autor:
Jayanta Sarkar, Rituraj Konwar, Mohd Quadir Siddiqui, Dhanaraju Mandalapu, Karan Singh Saini, Raghib Ashraf, Hamidullah, Sharmistha Das, Sonam Dwivedi, Vishnu L. Sharma
Publikováno v:
Molecular Carcinogenesis. 56:1266-1280
Targeting tumor DNA damage and p53 pathway is a clinically established strategy in the development of cancer chemotherapeutics. Majority of anti-cancer drugs are delivered through parenteral route for reasons like severe toxicity, lack of stability,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d650d6c5101ee96ca375354ef3e268b
https://doi.org/10.1002/mc.22588
https://doi.org/10.1002/mc.22588
Autor:
Rajeev Kumar, E. Ramakrishna, Rakesh Maurya, Hamidullah, Naibedya Chattopadhyay, Karan Singh Saini, Sudhir Kumar, Rituraj Konwar, Amit Kumar
Publikováno v:
Biochimie. 119:68-79
Pre-clinical studies suggest mitigating effect of dietary flavonoid quercetin against cancer and other diseases. However, quercetin suffers from poor metabolic stability, which appears to offset its pharmacological efficacy. Recently, we isolated que
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::687eb4fd8895aae249906f1c6c020726
https://doi.org/10.1016/j.biochi.2015.10.012
https://doi.org/10.1016/j.biochi.2015.10.012
Autor:
Karan Singh Saini, Hamidullah, Arindam Bhattacharjee, Kalyan Mitra, Sonam Dwivedi, Rama Pati Tripathi, Munna Prasad Gupt, Arya Ajay, Rituraj Konwar, Sharmistha Das, Himangsu K. Bora, N. Devender
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 65:275-287
Autophagy is considered as an important cell death mechanism that closely interacts with other common cell death programs like apoptosis. Critical role of autophagy in cell death makes it a promising, yet challenging therapeutic target for cancer. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa3fe3a7687c71cd8ecf6da0ad4da54
https://doi.org/10.1016/j.biocel.2015.06.016
https://doi.org/10.1016/j.biocel.2015.06.016
Publikováno v:
Agricultural Research Journal. 56:738
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acf1cf8fb148cfd48c57964aaacd451d
https://doi.org/10.5958/2395-146x.2019.00113.3
https://doi.org/10.5958/2395-146x.2019.00113.3