Výsledky vyhledávání - "Karan D. Bhatt"

Akademický článek

Deconvoluting complex correlates of COVID-19 severity with a multi-omic pandemic tracking strategy

Autor: Victoria N. Parikh, Alexander G. Ioannidis, David Jimenez-Morales, John E. Gorzynski, Hannah N. De Jong, Xiran Liu, Jonasel Roque, Victoria P. Cepeda-Espinoza, Kazutoyo Osoegawa, Chris Hughes, Shirley C. Sutton, Nathan Youlton, Ruchi Joshi, David Amar, Yosuke Tanigawa, Douglas Russo, Justin Wong, Jessie T. Lauzon, Jacob Edelson, Daniel Mas Montserrat, Yongchan Kwon, Simone Rubinacci, Olivier Delaneau, Lorenzo Cappello, Jaehee Kim, Massa J. Shoura, Archana N. Raja, Nathaniel Watson, Nathan Hammond, Elizabeth Spiteri, Kalyan C. Mallempati, Gonzalo Montero-Martín, Jeffrey Christle, Jennifer Kim, Anna Kirillova, Kinya Seo, Yong Huang, Chunli Zhao, Sonia Moreno-Grau, Steven G. Hershman, Karen P. Dalton, Jimmy Zhen, Jack Kamm, Karan D. Bhatt, Alina Isakova, Maurizio Morri, Thanmayi Ranganath, Catherine A. Blish, Angela J. Rogers, Kari Nadeau, Samuel Yang, Andra Blomkalns, Ruth O’Hara, Norma F. Neff, Christopher DeBoever, Sándor Szalma, Matthew T. Wheeler, Christian M. Gates, Kyle Farh, Gary P. Schroth, Phil Febbo, Francis deSouza, Omar E. Cornejo, Marcelo Fernandez-Vina, Amy Kistler, Julia A. Palacios, Benjamin A. Pinsky, Carlos D. Bustamante, Manuel A. Rivas, Euan A. Ashley

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)

There is a genetic component to the risk of severe COVID-19, but the genetic effects are difficult to separate from social constructs that covary with genetic ancestry. To address this, the authors identify determinants of COVID-19 severity using adm

Externí odkaz: https://doaj.org/article/10002eca5587461185e42393a7dc16a5

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Using genomic epidemiology of SARS-CoV-2 to support contact tracing and public health surveillance in rural Humboldt County, California

Autor: Angela M. Detweiler, Karan D. Bhatt, Norma Neff, Dan Lu, Jeremy Corrigan, Joseph L. DeRisi, Joshua Batson, Gunnar Stoddard, Michelle Tan, Patrick Ayscue, Jack Kamm, Allison Black, Amy Kistler, Lienna Chan

Publikováno v: BMC public health, vol 22, iss 1

Background During the COVID-19 pandemic within the United States, much of the responsibility for diagnostic testing and epidemiologic response has relied on the action of county-level departments of public health. Here we describe the integration of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381dab34cb290dc33e81aa93cd327168
https://doi.org/10.1186/s12889-022-12790-0

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Deconvoluting complex correlates of COVID-19 severity with a multi-omic pandemic tracking strategy

Publikováno v: Nature communications, vol 13, iss 1

The SARS-CoV-2 pandemic has differentially impacted populations across race and ethnicity. A multi-omic approach represents a powerful tool to examine risk across multi-ancestry genomes. We leverage a pandemic tracking strategy in which we sequence v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f118aae9b209086b4082f16691dd4607
https://pubmed.ncbi.nlm.nih.gov/36042219

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Deconvoluting complex correlates of COVID19 severity with local ancestry inference and viral phylodynamics: Results of a multiomic pandemic tracking strategy

Autor: Kinya Seo, Jennifer Kim, Douglas Russo, David Jimenez-Morales, Lorenzo Cappello, Nathaniel Watson, Manuel A. Rivas, Archana Raja, Nathan Hammond, Marcelo Fernandez-Vina, Francis deSouza, Nathan Youlton, Steven G. Hershman, Kazutoyo Osoegawa, Olivier Delaneau, Shirley Sutton, Jessie T. Lauzon, Andra L. Blomkalns, Ruth O'Hara, Yongchan Kwon, Amy Kistler, Victoria N. Parikh, Yong Huang, Carlos Bustamante, Matthew T. Wheeler, Elizabeth Spiteri, Benjamin A. Pinsky, Jonasel Roque, Simone Rubinacci, Massa J. Shoura, Thanmayi Ranganath, Samuel Yang, John E. Gorzynski, Alina Isakova, Gary P. Schroth, Kyle Kai-How Farh, Yosuke Tanigawa, Ruchi Joshi, Hannah N. De Jong, Kalyan C. Mallempati, Catherine A. Blish, Christopher R. Hughes, Norma Neff, Justin Wong, Karan D. Bhatt, Sándor Szalma, Julia A. Palacios, Jimmy Zhen, Jack Kamm, Alexander G. Ioannidis, Anna Kirillova, Xiran Liu, Gonzalo Montero-Martín, Angela J. Rogers, Jeffrey W. Christle, David Amar, Maurizio Morri, Karen P. Dalton, Phil Febbo, Jaehee Kim, Victoria P. Cepeda-Espinoza, Sonia Moreno-Grau, Chunli Zhao, Christopher DeBoever, Euan A. Ashley, Kari C. Nadeau, Jacob Edelson, Daniel Mas Montserrat

The SARS-CoV-2 pandemic has differentially impacted populations of varied race, ethnicity and socioeconomic status. Admixture mapping and local ancestry inference represent powerful tools to examine genetic risk within multi-ancestry genomes independ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aeee66778d9fd13a5991ed041ddf74c6
https://doi.org/10.1101/2021.08.04.21261547

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Identification of a Polymorphism in the N Gene of SARS-CoV-2 That Adversely Impacts Detection by Reverse Transcription-PCR

Publikováno v: Journal of Clinical Microbiology

Since April 7, 2020, our COVID-19 diagnostic laboratory (CLIAHUB) has received samples from multiple counties in California - our RT-PCR protocol (1) employs N-gene (NIID_2019-nCov_N_F2/R2ver3/P2 (Japan) (2)) and E-gene (E_Sarbeco_F/R/P1 (Germany) (3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09abaeb09acb14a67cfcc93553d9297f

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Identification of a polymorphism in the N gene of SARS-CoV-2 that adversely impacts detection by a widely-used RT-PCR assay

We identify a mutation in the N gene of SARS-CoV-2 that adversely affects annealing of a commonly used RT-PCR primer; epidemiologic evidence suggests the virus retains pathogenicity and competence for spread. This reinforces the importance of using m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b6dea16efcf10ad87e6ad1575608cbe
https://doi.org/10.1101/2020.08.25.265074

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