Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Karamjeet Pandher"'
Publikováno v:
International journal of medical sciences. 19(11)
RRx-001 is a small molecule NLRP3 inflammasome inhibitor with anti-CD47 and antiangiogenic/vascular normalization properties in a Phase 3 clinical trial that has been designated as a drug-device combination by the FDA. In the Phase 1 first-in-man dos
Autor:
Kelly R. Bales, Anabella Villalobos, David Riddell, Shawn D. Doran, Christopher Ryan Butler, Bruce N. Rogers, Lorraine F. Lanyon, Karamjeet Pandher, Claude Ambroise, Ashley Robshaw, Gabriela Barreiro, Christopher Houle, Kevin Ogilvie, Brian T. O’Neill, Erik Alphie Lachapelle, Germaine Boucher, Xinjun Hou, Katherine Hales, David Karanian, Michael Aaron Brodney, Leanne M. Buzon, Kimberly Lapham, Lei Zhang, Luis Martinez-Alsina, Charles E. Nolan, Claire M. Steppan, Cathleen Gonzales, John C. Murray, Cheng Chang, Jason K. Dutra, Elizabeth Mary Beck
Publikováno v:
Journal of Medicinal Chemistry. 61:4476-4504
A major challenge in the development of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors for the treatment of Alzheimer's disease is the alignment of potency, drug-like properties, and selectivity over related aspartyl proteases
Autor:
Hadi Falahatpisheh, Maryam Dehghani, Jane Morrow, Catherine Tsao, Steven Dorrow, Josh Stewart, Carine Bossard, Brian Eastman, Chi-Ching Mak, Karamjeet Pandher, Michael A. White
Publikováno v:
Molecular Cancer Therapeutics. 20:P250-P250
Proteome diversification through extensive pre-mRNA alternative splicing (AS) is a fundamental aspect of cell fate determination and tissue specialization. The CDC2-like kinases (CLK1-4) and the dual specificity tyrosine phosphorylation regulated kin
Autor:
Kelly R. Bales, David Karanian, Michael Aaron Brodney, Shawn D. Doran, Cathleen Gonzales, Katherine Hales, Germaine Boucher, Lorraine F. Lanyon, Charles E. Nolan, Karamjeet Pandher, Christopher Houle, Claude Ambroise, Cheng Chang
Publikováno v:
Alzheimer's & Dementia. 12
Publikováno v:
Toxicologic Pathology. 40:391-402
The first electron microscopic images of biological specimens were made in the 1940s, and the next 30 years comprised an era of descriptive ultrastructure during which transmission electron microscopy (TEM) was integral to an explosion in cellular an
Publikováno v:
ResearcherID
Four dead canine pups (5–12 days old) from 3 litters in Douglas County of north central Colorado were submitted to the Colorado State University Diagnostic Laboratory for necropsy. Pups were originally presented to the referring clinics for respira
Autor:
Ameesha Batheja, Mathew T. Pletcher, Alison H. Harrill, Paul B. Watkins, Merrie Mosedale, Hong Wu, Catherine L. Kurtz, Rachel J. Church, Susan Sumner, Karamjeet Pandher, Monica Singer, Wimal Pathmasiri, Karissa Adkins, John S. Eaddy
Isoniazid (INH), the mainstay therapeutic for tuberculosis infection, has been associated with rare but serious hepatotoxicity in the clinic. However, the mechanisms underlying inter-individual variability in the response to this drug have remained e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af650f83ece5d45e9d3b1a1aeb60e90
Autor:
George L. Murphy, Karamjeet Pandher
Publikováno v:
Veterinary Microbiology. 51:331-341
Pasteurella haemolytica serotype A1 is the bacterial pathogen most frequently isolated from the lungs of cattle with bovine respiratory disease. As part of a study to characterize P. haemolytica antigens which are important in eliciting resistance to
Autor:
John P. Isanhart, Russell K. MacRae, Michael J. Hooper, Hongmei Wu, Karamjeet Pandher, Stephen B. Cox
Publikováno v:
Archives of environmental contamination and toxicology. 61(4)
From September to November 2000, United States Fish and Wildlife Service biologists investigated incidents involving 221 bird deaths at 3 mine sites located in New Mexico and Arizona. These bird deaths primarily involved passerine and waterfowl speci
Publikováno v:
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 40(4)
A male ball python (Python regius) and a female blue tongue skink (Tiliqua spp.) of unknown age were evaluated for anorexia, lethargy, excessive shedding, corneal opacity (python), and weight loss (skink) of approximately three weeks' duration. These